MX9706402A - EMULSIaN DE GAS ESTABILIZADA, QUE CONTIENE FOSFOLIPIDOS PARA AUMENTAR EL CONTRASTE DEL ULTRASONIDO. - Google Patents
EMULSIaN DE GAS ESTABILIZADA, QUE CONTIENE FOSFOLIPIDOS PARA AUMENTAR EL CONTRASTE DEL ULTRASONIDO.Info
- Publication number
- MX9706402A MX9706402A MX9706402A MX9706402A MX9706402A MX 9706402 A MX9706402 A MX 9706402A MX 9706402 A MX9706402 A MX 9706402A MX 9706402 A MX9706402 A MX 9706402A MX 9706402 A MX9706402 A MX 9706402A
- Authority
- MX
- Mexico
- Prior art keywords
- surfactant
- gas
- gas emulsion
- emulsion containing
- contrast enhancement
- Prior art date
Links
- 150000003904 phospholipids Chemical class 0.000 title abstract 4
- 239000000839 emulsion Substances 0.000 title abstract 3
- 238000002604 ultrasonography Methods 0.000 title 1
- 239000004094 surface-active agent Substances 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000002872 contrast media Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
Abstract
Una composicion que forma una emulsion de gas, que comprende un material seco, hueco, particulado aproximadamente microesférico, permeado con un gas o una mezcla de gases, la cual, en la disolucion en un líquido acuoso, forma una emulsion de gas que comprende una pluralidad de burbujas rodeadas por una capa de cuando menos un primero y un segundo agente tensoactivo, en que el primer agente tensoactivo consiste esencialmente de un fosfolípido o una mezcla de fosfolípidos que tiene al menos una cadena de acilo, la cual comprende cuando menos 10 átomos de carbono y que comprende cuando menos aproximadamente el 5%, en peso/peso, del agente tensoactivo total, y en que el segundo agente tensoactivo puede o no ser un fosfolípido y es más soluble en agua que el primer agente tensoactivo equipos para preparar estas microburbujas; y métodos para usar las micro burbujas como agentes de contraste.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08395680 | 1995-02-28 | ||
| US08/395,680 US5798091A (en) | 1993-07-30 | 1995-02-28 | Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9706402A true MX9706402A (es) | 1998-08-30 |
| MXPA97006402A MXPA97006402A (es) | 1998-11-12 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| CN1182373A (zh) | 1998-05-20 |
| CN1182373B (zh) | 2010-12-08 |
| FI973496A0 (fi) | 1997-08-26 |
| CA2212113A1 (en) | 1996-09-06 |
| HUP9802095A3 (en) | 1999-03-29 |
| CA2212113C (en) | 2007-04-24 |
| US7141235B2 (en) | 2006-11-28 |
| US5798091A (en) | 1998-08-25 |
| AU4922196A (en) | 1996-09-18 |
| NO973489L (no) | 1997-08-27 |
| NO973489D0 (no) | 1997-07-30 |
| US6280705B1 (en) | 2001-08-28 |
| JP2005263804A (ja) | 2005-09-29 |
| AU731671B2 (en) | 2001-04-05 |
| KR100407755B1 (ko) | 2004-02-18 |
| HUP9802095A2 (hu) | 1999-01-28 |
| EP0812214A1 (en) | 1997-12-17 |
| FI973496A (fi) | 1997-08-26 |
| JPH11501305A (ja) | 1999-02-02 |
| US20020031476A1 (en) | 2002-03-14 |
| PL321952A1 (en) | 1998-01-05 |
| JP4229918B2 (ja) | 2009-02-25 |
| KR19980702548A (ko) | 1998-07-15 |
| WO1996026746A1 (en) | 1996-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or rights |
Owner name: IMCOR PHARMACEUTICAL CO. |
|
| FA | Abandonment or withdrawal |