MX9705144A - Uso de un compuesto de carboestirilo para preparar un inhibidor de la produccion o secrecion del factor de necrosis tumoral alfa. - Google Patents

Uso de un compuesto de carboestirilo para preparar un inhibidor de la produccion o secrecion del factor de necrosis tumoral alfa.

Info

Publication number
MX9705144A
MX9705144A MX9705144A MX9705144A MX9705144A MX 9705144 A MX9705144 A MX 9705144A MX 9705144 A MX9705144 A MX 9705144A MX 9705144 A MX9705144 A MX 9705144A MX 9705144 A MX9705144 A MX 9705144A
Authority
MX
Mexico
Prior art keywords
alpha
tnf
inhibition
alkyl
phenyl
Prior art date
Application number
MX9705144A
Other languages
English (en)
Other versions
MXPA97005144A (es
Inventor
Toyoki Mori
Michiaki Tominaga
Yukihisa Ono
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of MX9705144A publication Critical patent/MX9705144A/es
Publication of MXPA97005144A publication Critical patent/MXPA97005144A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

El uso de un compuesto de carboestirilo de la formula (I), en donde R1 es H o un alquilo inferior, y R2 es un grupo fenilalquilo (inferior) que tiene opcionalmente de 1 a 3 substituyentes alcoxi inferior en el anillo de fenilo, o una sal farmacéuticamente aceptable del mismo, para la preparacion de un inhibidor de la produccion o secrecion de FNT-alfa, para la profilaxis y tratamiento de enfermedades inducidas por secrecion acelerada de FNT-alfa, tal como artritis reumatoide, choque de endotoxina, síndrome de insuficiencia respiratoria en adultos, quemadura térmica, asma, infarto del miocardio, fase aguda de miocardiosis viral, etc.
MXPA/A/1997/005144A 1995-01-09 1997-07-08 Uso de un compuesto de carboestirilo para preparar un inhibidor de la produccion o secrecion delfactor de necrosis tumoral alfa MXPA97005144A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP93295 1995-01-09
JP7/932 1995-01-09
PCT/JP1995/002592 WO1996021447A1 (en) 1995-01-09 1995-12-18 Use of carbostyril compounds for inhibition of tnf-alpha

Publications (2)

Publication Number Publication Date
MX9705144A true MX9705144A (es) 1997-10-31
MXPA97005144A MXPA97005144A (es) 1998-07-03

Family

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Also Published As

Publication number Publication date
KR19980701286A (ko) 1998-05-15
AU694295B2 (en) 1998-07-16
US5886010A (en) 1999-03-23
AU4189496A (en) 1996-07-31
CA2209555A1 (en) 1996-07-18
WO1996021447A1 (en) 1996-07-18
AR001785A1 (es) 1997-12-10
CN1177296A (zh) 1998-03-25
EP0802793A1 (en) 1997-10-29

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal