MX9703101A - Proteina cinasa novedosa (npk-110). - Google Patents
Proteina cinasa novedosa (npk-110).Info
- Publication number
- MX9703101A MX9703101A MX9703101A MX9703101A MX9703101A MX 9703101 A MX9703101 A MX 9703101A MX 9703101 A MX9703101 A MX 9703101A MX 9703101 A MX9703101 A MX 9703101A MX 9703101 A MX9703101 A MX 9703101A
- Authority
- MX
- Mexico
- Prior art keywords
- protein kinase
- npk
- alzheimer
- maps
- cancer
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invencion se refiere a una secuencia de ADN que codifica una proteína cinasa neuronal (NPK) novedosa que fosforera proteínas tautoméricas así como otras proteínas asociadas de microtubulo (MARs) en posiciones cruciales para la union a Teorina y epítopes que comprenden dichos residuos fosforilados por dichos NPK o tales MAPs, a anticuerpos que se unen específicamente a dicha proteína cinasa, composiciones farmacéuticas que comprenden inhibidores para dicha proteína cinasa, en particular, para el tratamiento de enfermedad de Alzheimer y cáncer, a equipos de diagnostico y a métodos de diagnostico in vitro para la deteccion de enfermedad de Alzheimer y cáncer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94117122.5 | 1994-10-28 | ||
| EP94117122 | 1994-10-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9703101A true MX9703101A (es) | 1998-07-31 |
| MXPA97003101A MXPA97003101A (es) | 1998-11-09 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| DE69535901D1 (de) | 2009-01-29 |
| AU3870295A (en) | 1996-05-23 |
| US6579691B1 (en) | 2003-06-17 |
| KR100275591B1 (ko) | 2001-02-01 |
| NZ295371A (en) | 1998-11-25 |
| WO1996013592A2 (en) | 1996-05-09 |
| JPH10508199A (ja) | 1998-08-18 |
| HUT77081A (hu) | 1998-03-02 |
| CA2203910A1 (en) | 1996-05-09 |
| AU714636B2 (en) | 2000-01-06 |
| US20030104516A1 (en) | 2003-06-05 |
| EP0791067B1 (en) | 2008-12-17 |
| ATE417930T1 (de) | 2009-01-15 |
| US20040038361A1 (en) | 2004-02-26 |
| WO1996013592A3 (en) | 1996-08-01 |
| EP0791067A2 (en) | 1997-08-27 |
| NO971966L (no) | 1997-06-19 |
| US7485712B2 (en) | 2009-02-03 |
| CN1168699A (zh) | 1997-12-24 |
| NO971966D0 (no) | 1997-04-28 |
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