MX9702132A - Uso de un virus de adn no mamifero para expresar un gene exogeno en una celula de mamifero. - Google Patents

Uso de un virus de adn no mamifero para expresar un gene exogeno en una celula de mamifero.

Info

Publication number
MX9702132A
MX9702132A MX9702132A MX9702132A MX9702132A MX 9702132 A MX9702132 A MX 9702132A MX 9702132 A MX9702132 A MX 9702132A MX 9702132 A MX9702132 A MX 9702132A MX 9702132 A MX9702132 A MX 9702132A
Authority
MX
Mexico
Prior art keywords
mammalian
exogenous gene
cell
gene
express
Prior art date
Application number
MX9702132A
Other languages
English (en)
Other versions
MXPA97002132A (es
Inventor
Frederick M Boyce
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23205664&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9702132(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/US1995/011456 external-priority patent/WO1996009074A1/en
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Publication of MX9702132A publication Critical patent/MX9702132A/es
Publication of MXPA97002132A publication Critical patent/MXPA97002132A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Abstract

Se divulga un método de expresar un gene exogeno en una célula de mamífero, que implica infectar la célula con un virus no de mamífero, tal como un baculovirus, cuyo genoma lleva un gene exogeno, y cultivar la célula bajo condiciones tales que se exprese el gene. Los genes exogenos son entregados a las células de mamífero mediante el uso de un vector de transferencia tal que el descrito en el dibujo. También se divulga un método de tratar un desorden de deficiencia de gene en un mamífero proporcionando a una célula una cantidad terapéuticamente efectiva de un virus cuyo genoma lleva un gene exogeno y cultivar la célula bajo condiciones tales que el gene exogeno sea expresado en el mamífero.
MXPA/A/1997/002132A 1994-09-23 1997-03-20 Uso de un virus de adn no mamifero para expresar un gene exogeno en una celula de mamifero MXPA97002132A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08311157 1994-09-23
US08/311,157 US5871986A (en) 1994-09-23 1994-09-23 Use of a baculovirus to express and exogenous gene in a mammalian cell
PCT/US1995/011456 WO1996009074A1 (en) 1994-09-23 1995-09-08 Use of a non-mammalian dna virus to express an exogenous gene in a mammalian cell

Publications (2)

Publication Number Publication Date
MX9702132A true MX9702132A (es) 1997-11-29
MXPA97002132A MXPA97002132A (es) 1998-07-03

Family

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Also Published As

Publication number Publication date
US7192933B1 (en) 2007-03-20
ZA957797B (en) 1996-07-08
US5731182A (en) 1998-03-24
US5871986A (en) 1999-02-16

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