MX9701525A - Cristales de glicosidos de espiroestanilo. - Google Patents

Cristales de glicosidos de espiroestanilo.

Info

Publication number
MX9701525A
MX9701525A MX9701525A MX9701525A MX9701525A MX 9701525 A MX9701525 A MX 9701525A MX 9701525 A MX9701525 A MX 9701525A MX 9701525 A MX9701525 A MX 9701525A MX 9701525 A MX9701525 A MX 9701525A
Authority
MX
Mexico
Prior art keywords
crystals
spirostanyl
glycosidal
spirostanyl glycosidal
beta
Prior art date
Application number
MX9701525A
Other languages
English (en)
Inventor
Douglas J Allen
Richard A Buzon Jr
Michael P Dennino
Harry A Watson Jr
Jonathan B Zung
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX9701525A publication Critical patent/MX9701525A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Formas altamente cristalinas de (3 beta,5 alfa, 25r)-3-[( beta-D-4", 6"-bis-[2-fluorofenilcarbamoil]celobiosil)oxil]-es piroestan-12-ona que son utiles como agentes hipocolesterolemina o antiateroesclerosis.
MX9701525A 1994-08-30 1995-05-04 Cristales de glicosidos de espiroestanilo. MX9701525A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29810694A 1994-08-30 1994-08-30
PCT/IB1995/000317 WO1996006854A1 (en) 1994-08-30 1995-05-04 Spirostanyl glycosidal crystals

Publications (1)

Publication Number Publication Date
MX9701525A true MX9701525A (es) 1997-05-31

Family

ID=23149057

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9701525A MX9701525A (es) 1994-08-30 1995-05-04 Cristales de glicosidos de espiroestanilo.

Country Status (20)

Country Link
US (1) US5804562A (es)
EP (1) EP0778846A1 (es)
JP (1) JPH09510735A (es)
KR (1) KR970705574A (es)
AU (1) AU2265395A (es)
BR (1) BR9503827A (es)
CA (1) CA2198097A1 (es)
CO (1) CO4480032A1 (es)
FI (1) FI970828A0 (es)
HR (1) HRP950459A2 (es)
IL (1) IL115062A0 (es)
MA (1) MA23651A1 (es)
MX (1) MX9701525A (es)
NO (1) NO970910D0 (es)
OA (1) OA10402A (es)
PE (1) PE47696A1 (es)
PL (1) PL318937A1 (es)
SI (1) SI9520092A (es)
TR (1) TR199501065A2 (es)
WO (1) WO1996006854A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3768100B2 (ja) * 1998-03-26 2006-04-19 ファイトファーム・ピーエルシー アルツハイマー病を治療するためのステロイドサポゲニンとその誘導体
GB9923076D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB9923077D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
GB0107822D0 (en) * 2001-03-28 2001-05-23 Phytopharm Plc Sapogenin derivatives their synthesis and use methods based upon their use
CN102727501A (zh) * 2002-03-27 2012-10-17 菲特法姆股份有限公司 皂角苷配基及其衍生物的用途
US20050130948A1 (en) * 2002-03-27 2005-06-16 Daryl Rees Therapeutic methods and uses of sapogenins and their derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK158394A3 (en) * 1992-06-26 1995-05-10 Pfizer Steroidal glycosides
WO1995018144A1 (en) * 1993-12-28 1995-07-06 Pfizer Inc. Steroidal glycosides

Also Published As

Publication number Publication date
SI9520092A (en) 1997-12-31
US5804562A (en) 1998-09-08
FI970828A (fi) 1997-02-27
IL115062A0 (en) 1995-12-08
NO970910L (no) 1997-02-27
FI970828A0 (fi) 1997-02-27
JPH09510735A (ja) 1997-10-28
OA10402A (en) 2001-12-05
WO1996006854A1 (en) 1996-03-07
AU2265395A (en) 1996-03-22
CA2198097A1 (en) 1996-03-07
HRP950459A2 (en) 1997-08-31
MA23651A1 (fr) 1996-04-01
KR970705574A (ko) 1997-10-09
NO970910D0 (no) 1997-02-27
EP0778846A1 (en) 1997-06-18
BR9503827A (pt) 1996-09-10
CO4480032A1 (es) 1997-07-09
TR199501065A2 (tr) 1996-06-21
PE47696A1 (es) 1996-11-12
PL318937A1 (en) 1997-07-21

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