MX9605352A - Nuevos analogos peptidicos opioides con propiedades mezcladas agonista mu/antagonista delta. - Google Patents

Nuevos analogos peptidicos opioides con propiedades mezcladas agonista mu/antagonista delta.

Info

Publication number
MX9605352A
MX9605352A MX9605352A MX9605352A MX9605352A MX 9605352 A MX9605352 A MX 9605352A MX 9605352 A MX9605352 A MX 9605352A MX 9605352 A MX9605352 A MX 9605352A MX 9605352 A MX9605352 A MX 9605352A
Authority
MX
Mexico
Prior art keywords
agonist
mixed
peptide analogs
antagonist properties
opioid peptide
Prior art date
Application number
MX9605352A
Other languages
English (en)
Inventor
Peter Schiller
Ralf Schmidt
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of MX9605352A publication Critical patent/MX9605352A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4732—Casein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C07K5/126—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describen compuestos de la formula I, así como métodos para su preparacion, sus preparaciones farmacéuticas y su uso como analgésico.
MX9605352A 1994-05-06 1995-04-27 Nuevos analogos peptidicos opioides con propiedades mezcladas agonista mu/antagonista delta. MX9605352A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9401596A SE9401596D0 (sv) 1994-05-06 1994-05-06 New compounds
PCT/SE1995/000462 WO1995030694A1 (en) 1994-05-06 1995-04-27 New opioid peptide analogs with mixed mu agonist/delta antagonist properties

Publications (1)

Publication Number Publication Date
MX9605352A true MX9605352A (es) 1997-12-31

Family

ID=20393941

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9605352A MX9605352A (es) 1994-05-06 1995-04-27 Nuevos analogos peptidicos opioides con propiedades mezcladas agonista mu/antagonista delta.

Country Status (19)

Country Link
US (1) US5786447A (es)
EP (1) EP0763062A1 (es)
JP (1) JPH10500404A (es)
CN (1) CN1147819A (es)
AU (1) AU688040B2 (es)
BR (1) BR9507620A (es)
CA (1) CA2188670A1 (es)
FI (1) FI964443A (es)
HU (1) HU9603065D0 (es)
IL (1) IL113441A0 (es)
IS (1) IS4377A (es)
MX (1) MX9605352A (es)
NO (1) NO964670D0 (es)
NZ (1) NZ285476A (es)
PL (1) PL317049A1 (es)
SE (1) SE9401596D0 (es)
SK (1) SK136596A3 (es)
WO (1) WO1995030694A1 (es)
ZA (1) ZA953315B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6703381B1 (en) 1998-08-14 2004-03-09 Nobex Corporation Methods for delivery therapeutic compounds across the blood-brain barrier
AUPP616498A0 (en) * 1998-09-25 1998-10-15 University Of Queensland, The Synthesis of cyclic peptides
US10010617B2 (en) * 2011-05-18 2018-07-03 Eumederis Pharmaceuticals, Inc. Peptide pharmaceuticals

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0680079B2 (ja) * 1984-11-09 1994-10-12 エーザイ株式会社 ポリペプチド

Also Published As

Publication number Publication date
US5786447A (en) 1998-07-28
IS4377A (is) 1996-10-21
WO1995030694A1 (en) 1995-11-16
EP0763062A1 (en) 1997-03-19
IL113441A0 (en) 1995-07-31
BR9507620A (pt) 1997-08-19
NZ285476A (en) 1998-04-27
CA2188670A1 (en) 1995-11-16
FI964443A0 (fi) 1996-11-05
CN1147819A (zh) 1997-04-16
SK136596A3 (en) 1997-06-04
FI964443A (fi) 1996-11-05
NO964670L (no) 1996-11-05
AU2458395A (en) 1995-11-29
PL317049A1 (en) 1997-03-03
SE9401596D0 (sv) 1994-05-06
HU9603065D0 (en) 1997-01-28
JPH10500404A (ja) 1998-01-13
ZA953315B (en) 1995-11-06
AU688040B2 (en) 1998-03-05
NO964670D0 (no) 1996-11-05

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