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Priority claimed from KR1019950043607Aexternal-prioritypatent/KR0162710B1/en
Application filed by Samjin Pharm Co LtdfiledCriticalSamjin Pharm Co Ltd
Priority claimed from PCT/KR1996/000005external-prioritypatent/WO1996021648A1/en
Publication of MX9603308ApublicationCriticalpatent/MX9603308A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
The present invention relates to novel compound of general formula (I) and acid addition salt thereof, wherein R1 and R2 are independently hydrogen, C1-C8 alkyl or optionally substituted C3-C6 membered cycloalkyl containing C3-C8; R3, R4, R5, R6 and R7 are independently hydrogen, halogen, hydroxy, nitro, C1-C4 lower ester, C1-C4 lower alkyl, C1-C4 lower alkoxy, aryl, arylalkoxy or unsaturated amine; 1 is an integer of 0-7; m and n are independently an integer of 0-1; W is carbon or nitrogen; X is oxygen, sulfur, optionally substituted imine; Y is nitrogen or oxygen; and Z is hydrogen, C1-C8 alkoxy, aryloxy, C1-C4 alkylamine, cycloamine containing N1-N5 or oxo group. The present compounds of the above formula (I) have not only strong antitumor activities but lower toxicities, and accordingly are expected as novel antitumor agents.
MX9603308A1995-01-111996-01-10New piperazine derivatives and methods for the preparation thereof and compositions containing the same.
MX9603308A
(en)
Piperidyl - urea, - thiourea and - guanidine derivatives, and intermediates therefor, processes for preparing them and pharmaceutical compositions containing the derivatives.
Novel branched substituted amino derivatives of 3-amino-1- phenyl-1h(1,2,4)triazol,methods for producing them and pharmaceutical compositions containing them
NOVEL OCTAHYDRO-6,10-DIOXO-6H-PYRIDAZINO/1,2-a/ /1,2/DIAZEPIN-1-CARBOXYLIC ACID DERIVATIVES, PREPARATION METHOD AND USE FOR PREPARING THERAPEUTICALLY ACTIVE COMPOUNDS