MX9302853A - ENZYMATIC PROCESS TO PRODUCE ACID (S) -6-METOXI-ALPHA-METHYL-2-NAFTALENEACETIC. - Google Patents

ENZYMATIC PROCESS TO PRODUCE ACID (S) -6-METOXI-ALPHA-METHYL-2-NAFTALENEACETIC.

Info

Publication number
MX9302853A
MX9302853A MX9302853A MX9302853A MX9302853A MX 9302853 A MX9302853 A MX 9302853A MX 9302853 A MX9302853 A MX 9302853A MX 9302853 A MX9302853 A MX 9302853A MX 9302853 A MX9302853 A MX 9302853A
Authority
MX
Mexico
Prior art keywords
naftaleneacetic
metoxi
alpha
methyl
enzymatic process
Prior art date
Application number
MX9302853A
Other languages
Spanish (es)
Inventor
Steven R Beck
Robert O Cain
Hardy W Chan
Richard Freedman
Donald L Heefner
Patricia Phelps
Christopher R Roberts
Felix H Salazar
Roger C Snyder
Original Assignee
Syntex Pharma Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Pharma Int filed Critical Syntex Pharma Int
Publication of MX9302853A publication Critical patent/MX9302853A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00—Other engines
    • F02B75/02—Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

Abstract

Se describe una hidrólisis enantioselectiva de ésteres de naproxen racémicos mediante éster-hidrolasas microorganismos, el más adecuado de los cuales fue el organismo Zopfields Latipes. Las éster-hidrolasa son útiles en una hidrólisis de bajo costo, alto rendimiento, de ésteres de naproxen racémicos.We describe an enantioselective hydrolysis of racemic naproxen esters by ester-hydrolase microorganisms, the most suitable of which was the Zopfields Latipes organism. Ester hydrolases are useful in a low cost, high performance hydrolysis of racemic naproxen esters.

MX9302853A 1992-05-15 1993-05-14 ENZYMATIC PROCESS TO PRODUCE ACID (S) -6-METOXI-ALPHA-METHYL-2-NAFTALENEACETIC. MX9302853A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88365892A 1992-05-15 1992-05-15

Publications (1)

Publication Number Publication Date
MX9302853A true MX9302853A (en) 1993-11-01

Family

ID=25383055

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9302853A MX9302853A (en) 1992-05-15 1993-05-14 ENZYMATIC PROCESS TO PRODUCE ACID (S) -6-METOXI-ALPHA-METHYL-2-NAFTALENEACETIC.

Country Status (5)

Country Link
EP (1) EP0644940A1 (en)
FI (1) FI945353A (en)
MX (1) MX9302853A (en)
NO (1) NO944336L (en)
WO (1) WO1993023547A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9304351D0 (en) * 1993-03-03 1993-04-21 Chiros Ltd Arylalkanoic acid resolution and microorganisms for use therein
US5912164A (en) * 1993-03-03 1999-06-15 Laboratorios Menarini S.A. Stereoselective hydrolysis of chiral carboxylic acid esters using esterase from ophiostoma or ceratocystis
HUE030906T2 (en) 2009-09-30 2017-06-28 Codexis Inc Improved lov-d acyltransferase mediated acylation
CN103937845B (en) * 2014-04-24 2016-06-22 哈尔滨商业大学 S-(+) preparation method of-naproxen acylglycerol ester prodrugs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU599944B2 (en) * 1985-12-20 1990-08-02 Wisconsin Alumni Research Foundation Process for preparing (S)-alpha-methylarylacetic acids
AU619249B2 (en) * 1988-02-25 1992-01-23 Istituto Guido Donegani S.P.A. Process for the continuous biotechnological preparation of optical isomer s(+) of 2-(6-methoxy-2-naphthyl) propionic acid
FI95931C (en) * 1988-09-02 1996-04-10 Tanabe Seiyaku Co Process for the preparation of the lower alkyl ester of (2R, 3S) -3- (4-methoxyphenyl) glycidic acid

Also Published As

Publication number Publication date
FI945353A0 (en) 1994-11-14
FI945353A (en) 1994-11-14
WO1993023547A1 (en) 1993-11-25
EP0644940A1 (en) 1995-03-29
NO944336D0 (en) 1994-11-14
NO944336L (en) 1994-11-14

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