FI945353A - Enzymatic process for the preparation of (S) -6-methoxyl-alpha-methyl-2-naphthaleneacetic acid - Google Patents

Enzymatic process for the preparation of (S) -6-methoxyl-alpha-methyl-2-naphthaleneacetic acid Download PDF

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Publication number
FI945353A
FI945353A FI945353A FI945353A FI945353A FI 945353 A FI945353 A FI 945353A FI 945353 A FI945353 A FI 945353A FI 945353 A FI945353 A FI 945353A FI 945353 A FI945353 A FI 945353A
Authority
FI
Finland
Prior art keywords
methoxyl
alpha
methyl
preparation
enzymatic process
Prior art date
Application number
FI945353A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI945353A0 (en
Inventor
Hardy W Chan
Richard Freedman
Felix H Salazar
Steven R Beck
Robert O Cain
Christopher R Roberts
Roger C Synder
Patricia Phelps
Donald L Heefner
Original Assignee
Syntex Pharma Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Pharma Int filed Critical Syntex Pharma Int
Publication of FI945353A publication Critical patent/FI945353A/en
Publication of FI945353A0 publication Critical patent/FI945353A0/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00—Other engines
    • F02B75/02—Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
FI945353A 1992-05-15 1994-11-14 Enzymatic process for the preparation of (S) -6-methoxyl-alpha-methyl-2-naphthaleneacetic acid FI945353A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88365892A 1992-05-15 1992-05-15
PCT/US1993/004392 WO1993023547A1 (en) 1992-05-15 1993-05-14 ENZYMATIC PROCESS FOR PRODUCTION OF S-6-METHOXY-α-METHYL-2-NAPHTHALENEACETIC ACID

Publications (2)

Publication Number Publication Date
FI945353A true FI945353A (en) 1994-11-14
FI945353A0 FI945353A0 (en) 1994-11-14

Family

ID=25383055

Family Applications (1)

Application Number Title Priority Date Filing Date
FI945353A FI945353A0 (en) 1992-05-15 1994-11-14 Enzymatic process for the preparation of (S) -6-methoxyl-alpha-methyl-2-naphthaleneacetic acid

Country Status (5)

Country Link
EP (1) EP0644940A1 (en)
FI (1) FI945353A0 (en)
MX (1) MX9302853A (en)
NO (1) NO944336L (en)
WO (1) WO1993023547A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912164A (en) * 1993-03-03 1999-06-15 Laboratorios Menarini S.A. Stereoselective hydrolysis of chiral carboxylic acid esters using esterase from ophiostoma or ceratocystis
GB9304351D0 (en) * 1993-03-03 1993-04-21 Chiros Ltd Arylalkanoic acid resolution and microorganisms for use therein
DK3190123T3 (en) 2009-09-30 2019-09-30 Codexis Inc IMPROVED LAW-D ACYL TRANSFERASE MEDIATED ACYLATION
CN103937845B (en) * 2014-04-24 2016-06-22 哈尔滨商业大学 S-(+) preparation method of-naproxen acylglycerol ester prodrugs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0227078A1 (en) * 1985-12-20 1987-07-01 Wisconsin Alumni Research Foundation Process for preparing (S)-alpha-methylarylacetic acids
US5229280A (en) * 1988-02-25 1993-07-20 Istituto Guido Donegani S.P.A. Process for the continuous biotechnological preparation of optical isomer s(+) of 2-(6-methoxy-2-naphthyl) propionic acid
IL91453A0 (en) * 1988-09-02 1990-04-29 Tanabe Seiyaku Co Preparation of optically active 3-phenyl-glycidic acid esters

Also Published As

Publication number Publication date
MX9302853A (en) 1993-11-01
NO944336D0 (en) 1994-11-14
FI945353A0 (en) 1994-11-14
NO944336L (en) 1994-11-14
WO1993023547A1 (en) 1993-11-25
EP0644940A1 (en) 1995-03-29

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Legal Events

Date Code Title Description
FD Application lapsed