MX9205726A - Derivados de 4'-(n-substituido-n-oxido) estaurosporina. - Google Patents

Derivados de 4'-(n-substituido-n-oxido) estaurosporina.

Info

Publication number
MX9205726A
MX9205726A MX9205726A MX9205726A MX9205726A MX 9205726 A MX9205726 A MX 9205726A MX 9205726 A MX9205726 A MX 9205726A MX 9205726 A MX9205726 A MX 9205726A MX 9205726 A MX9205726 A MX 9205726A
Authority
MX
Mexico
Prior art keywords
staurosporin
derivatives
substituted
oxide
Prior art date
Application number
MX9205726A
Other languages
English (en)
Inventor
Michael P Kirkup
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MX9205726A publication Critical patent/MX9205726A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX9205726A 1991-10-10 1992-10-06 Derivados de 4'-(n-substituido-n-oxido) estaurosporina. MX9205726A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77439591A 1991-10-10 1991-10-10

Publications (1)

Publication Number Publication Date
MX9205726A true MX9205726A (es) 1993-04-01

Family

ID=25101107

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9205726A MX9205726A (es) 1991-10-10 1992-10-06 Derivados de 4'-(n-substituido-n-oxido) estaurosporina.

Country Status (4)

Country Link
EP (1) EP0540185A1 (es)
AU (1) AU2866992A (es)
MX (1) MX9205726A (es)
WO (1) WO1993007153A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69331228T4 (de) * 1992-09-21 2002-09-05 Kyowa Hakko Kogyo Kk Heilmittel für thrombozytopenia
GB9325395D0 (en) * 1993-12-11 1994-02-16 Ciba Geigy Ag Compositions
RU2337692C3 (ru) 2001-10-30 2020-11-09 Новартис Аг Производные стауроспорина в качестве ингибиторов активности рецепторной тирозинкиназы flt3
WO2005014004A1 (en) 2003-08-08 2005-02-17 Novartis Ag Combinations comprising staurosporines
WO2006002422A2 (en) 2004-06-24 2006-01-05 Novartis Vaccines And Diagnostics Inc. Compounds for immunopotentiation
JP5704785B2 (ja) * 2004-07-19 2015-04-22 ザ・ジョンズ・ホプキンス・ユニバーシティ 免疫抑制のためのｆｌｔ３阻害剤
JO2660B1 (en) 2006-01-20 2012-06-17 نوفارتيس ايه جي Pi-3 inhibitors and methods of use
AR060358A1 (es) 2006-04-06 2008-06-11 Novartis Vaccines & Diagnostic Quinazolinas para la inhibicion de pdk 1
CA2710122A1 (en) 2007-12-20 2009-07-02 Novartis Ag Thiazole derivatives used as pi 3 kinase inhibitors
US8293753B2 (en) 2009-07-02 2012-10-23 Novartis Ag Substituted 2-carboxamide cycloamino ureas
AR082418A1 (es) 2010-08-02 2012-12-05 Novartis Ag Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
ES2611885T3 (es) 2011-01-31 2017-05-11 Novartis Ag Derivados heterocíclicos novedosos
PL2771342T3 (pl) 2011-10-28 2016-11-30 Nowe pochodne puryny i ich zastosowanie w leczeniu chorób
SG10201608469RA (en) 2012-05-16 2016-11-29 Novartis Ag Dosage regimen for a pi-3 kinase inhibitor
CN105979947A (zh) 2013-12-06 2016-09-28 诺华股份有限公司 α-同工型选择性磷脂酰肌醇3-激酶抑制剂的剂量方案
TWI538914B (zh) * 2014-10-03 2016-06-21 國立交通大學 蛋白質激酶之選擇性抑制劑、其醫藥組成物及其用途
EP3370719A1 (en) 2015-11-02 2018-09-12 Novartis AG Dosage regimen for a phosphatidylinositol 3-kinase inhibitor
WO2018060833A1 (en) 2016-09-27 2018-04-05 Novartis Ag Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
WO2019215759A1 (en) * 2018-05-09 2019-11-14 Alaparthi Lakshmi Prasad An improved process for preparation of midostaurin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5373501A (en) * 1976-12-11 1978-06-30 Kitasato Inst Novel antibiotics amm2282 and process for preparing same
JPS60185719A (ja) * 1984-03-06 1985-09-21 Ajinomoto Co Inc 抗腫瘍剤
IL86632A0 (en) * 1987-06-15 1988-11-30 Ciba Geigy Ag Derivatives substituted at methyl-amino nitrogen
JP2766360B2 (ja) * 1988-02-04 1998-06-18 協和醗酵工業株式会社 スタウロスポリン誘導体
WO1991009034A1 (en) * 1989-12-14 1991-06-27 Schering Corporation Indolocarbazoles from saccharothrix aerocolonigenes subsp. copiosa subsp. nov. scc 1951 atcc 53856

Also Published As

Publication number Publication date
AU2866992A (en) 1993-05-03
EP0540185A1 (en) 1993-05-05
WO1993007153A1 (en) 1993-04-15

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