MX9204831A - Un metodo para hacer capsulas biocompatibles que contienen celulas. - Google Patents

Un metodo para hacer capsulas biocompatibles que contienen celulas.

Info

Publication number
MX9204831A
MX9204831A MX9204831A MX9204831A MX9204831A MX 9204831 A MX9204831 A MX 9204831A MX 9204831 A MX9204831 A MX 9204831A MX 9204831 A MX9204831 A MX 9204831A MX 9204831 A MX9204831 A MX 9204831A
Authority
MX
Mexico
Prior art keywords
drops
cells
predialized
subjecting
semi
Prior art date
Application number
MX9204831A
Other languages
English (en)
Inventor
Heather Anne Clayton
Roger Frank Lever
James London Nicholas
John Milton
Original Assignee
Univ Leicester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919117980A external-priority patent/GB9117980D0/en
Priority claimed from GB929207143A external-priority patent/GB9207143D0/en
Application filed by Univ Leicester filed Critical Univ Leicester
Publication of MX9204831A publication Critical patent/MX9204831A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

Se describe un método para hacer cápsulas biocompatibles que contienen células que comprende los pasos de suspender células en un medio acuoso que contiene goma soluble en agua predializada que tiene porciones aniónicas plurales pero está sustancialmente libre de proteínas, formar la suspensión en gotas conteniendo las células, someter las gotas a una solución de cationes multivalentes fisiológicamente compatibles a gel en gotas, encapsular dichas células, someter dichas gotas gelificadas a un polímero que contiene grupos catiónicos que se entrelazan con grupos aniónicos para formar una membrana semipermeable y revestir dicha membrana semipermeable con una capa de dicha goma soluble en agua predializada.
MX9204831A 1991-08-20 1992-08-20 Un metodo para hacer capsulas biocompatibles que contienen celulas. MX9204831A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919117980A GB9117980D0 (en) 1991-08-20 1991-08-20 A method of making biocompatible capsules containing cells
GB929207143A GB9207143D0 (en) 1992-04-01 1992-04-01 A method of making biocompatible capsules containing cells

Publications (1)

Publication Number Publication Date
MX9204831A true MX9204831A (es) 1993-07-01

Family

ID=26299426

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9204831A MX9204831A (es) 1991-08-20 1992-08-20 Un metodo para hacer capsulas biocompatibles que contienen celulas.

Country Status (13)

Country Link
US (1) US5529913A (es)
EP (1) EP0599942B1 (es)
JP (1) JPH06510035A (es)
AT (1) ATE152616T1 (es)
AU (1) AU2443392A (es)
CA (1) CA2115664A1 (es)
DE (1) DE69219606T2 (es)
DK (1) DK0599942T3 (es)
ES (1) ES2101863T3 (es)
GR (1) GR3024007T3 (es)
IL (1) IL102785A (es)
MX (1) MX9204831A (es)
WO (1) WO1993003710A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9414304D0 (en) * 1994-07-15 1994-09-07 C V Lab Ltd Fibres, manufacture and use
AU1557000A (en) * 1998-11-20 2000-06-13 Autonomous University of Barcelona, The Insulin production by engineered muscle cells
US6921412B1 (en) 1999-05-18 2005-07-26 Cryolife, Inc. Self-supporting, shaped, three-dimensional biopolymeric materials and methods
ATE431165T1 (de) * 2000-01-25 2009-05-15 Edwards Lifesciences Corp Bioaktive beschichtungen zur vermeidung von gewebewachstum auf künstlichen herzklappen
AU9118201A (en) 2000-09-20 2002-04-02 Islet Sheet Medical Llc Improved methods for fabrication of thin sheet bio-artificial organs
EP1416946B1 (en) * 2000-11-07 2017-12-20 CryoLife, Inc. Expandable foam-like biomaterials and methods
US20060246111A1 (en) * 2005-04-19 2006-11-02 Smith Larry L Polysaccharides as ultrasound transmission media
WO2012130567A1 (en) * 2011-03-29 2012-10-04 Beta-Cell Nv Method for encapsulated therapeutic products and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO158284C (no) * 1981-03-13 1988-08-17 Damon Biotech Inc Fremgangsmaate for selektiv oppbrytning av en permeabel membran.
EP0301777A1 (en) * 1987-07-28 1989-02-01 Queen's University At Kingston Multiple membrane microencapsulation
US4923645A (en) * 1987-11-16 1990-05-08 Damon Biotech, Inc. Sustained release of encapsulated molecules

Also Published As

Publication number Publication date
JPH06510035A (ja) 1994-11-10
EP0599942A1 (en) 1994-06-08
GR3024007T3 (en) 1997-10-31
DE69219606T2 (de) 1997-09-04
EP0599942B1 (en) 1997-05-07
IL102785A0 (en) 1993-01-31
AU2443392A (en) 1993-03-16
US5529913A (en) 1996-06-25
DE69219606D1 (de) 1997-06-12
DK0599942T3 (da) 1997-11-03
ES2101863T3 (es) 1997-07-16
IL102785A (en) 1998-06-15
CA2115664A1 (en) 1993-03-04
ATE152616T1 (de) 1997-05-15
WO1993003710A1 (en) 1993-03-04

Similar Documents

Publication Publication Date Title
ES2035194T5 (es) Un procedimiento para fabricar membranas asimetricas de permeabilidad selectiva adecuadas para hemodialisis y las membranas asi preparadas.
AU578164B2 (en) Hollow fibre membrane, method of manufacture thereof, and artificial lung using said membrane
MX9204831A (es) Un metodo para hacer capsulas biocompatibles que contienen celulas.
IT1149365B (it) Procedimento per la produzione di una membrana di filamenti cavi asimmetrica costituita da poliammide
SE8002357L (sv) Inkapsling av levande vevnad och vevnadsimplantationsmetod
EP1249268A3 (en) Potting method to reduce fibre twinning
ATA86885A (de) Verfahren zur herstellung lagerstabiler, schnellzerfallender pharmazeutischer wirkstoff-presslinge
MX170594B (es) Sistema y metodo de filtracion para tratar una emulsion que contiene agua, aceite o grasa, un detergente anionico y material solido insoluble
ATE71289T1 (de) Paucilamellare lipidvesikel.
ES2018243B3 (es) Metodo para la preparacion de una membrana semipermeable compuesta
DE3880886D1 (de) Sol-gel-verfahren zur herstellung von glaesern mit ultraniedriger ausdehnung.
DE3886822D1 (de) Verfahren zur Herstellung von hochdurchlässigen zusammengesetzten beschichteten Hohlfasermembranen.
DE68916278D1 (de) Kontinuierliches Verfahren zur Herstellung von zusammengesetzten beschichteten Hohlfasermembranen.
DE3785838D1 (de) Verfahren zur herstellung von hochdruckplatten.
ATE128621T1 (de) Beladungstechnik zur herstellung arzneistoffhaltiger liposomen.
ES2088016T3 (es) Procedimiento para la preparacion de glucolipidos purificados mediante un procedimiento de separacion por membrana.
ES550423A0 (es) Un metodo para la fabricacion de una fibra optica.
AR220972A1 (es) Metodo mejorado para fabricar una membrana de fibra hueca anisotropica y la membrana producida
ES552301A0 (es) Un procedimiento para la produccion de una fibra optica de vidrio.
AU2455688A (en) Porous hollow fiber membrane, method for production thereof, and oxygenator using the hollow fiber membrane
AT383492B (de) Verfahren zur herstellung von stabilen weichgelatinekapseln unter einsatz von fluessigen mutterkornalkaloidloesungen
ES2172700T3 (es) Procedimiento para producir fibras hibridas altamente absorbentes por ozonizacion y polimerizacion por injertado, y fibras hibridas obtenidas por este procedimiento.
DE3582755D1 (de) Verfahren zur herstellung salzarmer, fluessiger, waessriger zubereitungen von faserreaktiven farbstoffen.
ES2032323T3 (es) Un procedimiento para la produccion de una preparacion antifungica formadora de pelicula.
ES555150A0 (es) Un procedimiento para la preparacion de una solucion etanolica contra la caida del cabello, a base de extractos naturales de plantas

Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees