MX9203134A - Esteres de hexahidro-8-hidroxi-2,6-metano-2h-quinolizin-3-(4h)-ona y compuestos relacionados. - Google Patents

Esteres de hexahidro-8-hidroxi-2,6-metano-2h-quinolizin-3-(4h)-ona y compuestos relacionados.

Info

Publication number
MX9203134A
MX9203134A MX9203134A MX9203134A MX9203134A MX 9203134 A MX9203134 A MX 9203134A MX 9203134 A MX9203134 A MX 9203134A MX 9203134 A MX9203134 A MX 9203134A MX 9203134 A MX9203134 A MX 9203134A
Authority
MX
Mexico
Prior art keywords
quinolizin
hexahydro
methane
hydroxy
esters
Prior art date
Application number
MX9203134A
Other languages
English (en)
Inventor
Maurice W Gittos
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of MX9203134A publication Critical patent/MX9203134A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX9203134A 1986-11-03 1992-06-23 Esteres de hexahidro-8-hidroxi-2,6-metano-2h-quinolizin-3-(4h)-ona y compuestos relacionados. MX9203134A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92661986A 1986-11-03 1986-11-03
US18563188A 1988-04-26 1988-04-26
US07/376,172 US4906755A (en) 1986-11-03 1989-06-30 Esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3-(4H)-one and related compounds

Publications (1)

Publication Number Publication Date
MX9203134A true MX9203134A (es) 1992-07-01

Family

ID=27391990

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9203134A MX9203134A (es) 1986-11-03 1992-06-23 Esteres de hexahidro-8-hidroxi-2,6-metano-2h-quinolizin-3-(4h)-ona y compuestos relacionados.

Country Status (2)

Country Link
US (1) US4906755A (es)
MX (1) MX9203134A (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0291172B1 (en) * 1987-04-14 1992-11-19 Glaxo Group Limited Ketone derivatives
EP0492020A1 (en) * 1990-12-21 1992-07-01 Merrell Dow Pharmaceuticals Inc. Use of certain esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and related compounds for treating cognitive disorders
US5955470A (en) * 1991-06-11 1999-09-21 Merrell Pharmaceuticals, Inc. Derivatives of amide analogs of certain methano bridged quinolizines
AU656217B2 (en) * 1991-08-09 1995-01-27 Aventisub Ii Inc. Use of quinozilinederivatives as orexigenics
DK0533280T4 (da) 1991-09-20 2005-02-28 Glaxo Group Ltd Ny medicinsk anvendelse af tachykininantagonister
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
JP5690461B2 (ja) * 2002-11-15 2015-03-25 ヘルシン ヘルスケア ソシエテ アノニム 化学療法誘導嘔吐を治療するためのパロノセトロン
JO2735B1 (en) * 2003-01-30 2013-09-15 هيلسين هيلث كير أس ايه. Liquid pharmaceutical formations of balloonosterone
US8598219B2 (en) 2003-01-30 2013-12-03 Helsinn Healthcare Sa Liquid pharmaceutical formulations of palonosetron
TWI355936B (en) 2003-02-18 2012-01-11 Helsinn Healthcare Sa Uses of palonosetron hydrochloride
US20060167072A1 (en) * 2004-01-30 2006-07-27 Helsinn Healthcare Sa Liquid pharmaceutical formulations of palonosetron
CN100390172C (zh) * 2004-09-10 2008-05-28 成都欣捷高新技术开发有限公司 一种甲磺酸多拉司琼晶型及其制备方法
WO2006056081A1 (de) * 2004-11-25 2006-06-01 Cilag Ltd. Verfahren zur herstellung von estern von hexahydro-8-hydroxy-2,6-methano-2h-chinolizin-3(4h)-on
WO2007072506A2 (en) * 2005-12-23 2007-06-28 Usv Limited Polymorphic forms of dolasetron mesylate and processes thereof
WO2007081890A2 (en) * 2006-01-05 2007-07-19 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Production of dolasetron
US20080004260A1 (en) * 2006-06-29 2008-01-03 Transcept Pharmaceuticals, Inc. Compositions of 5-HT3 antagonists and dopamine D2 antagonists for treatment of dopamine-associated chronic conditions
SI1940366T1 (sl) * 2006-10-24 2009-08-31 Helsinn Healthcare Sa Mehke kapsule, ki obsegajo palonosetron hidroklorid, z izboljšano stabilnostjo in biorazpoložljivostjo
WO2009014680A2 (en) * 2007-07-20 2009-01-29 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Polymorphs of dolasetron base and process for preparation thereof
WO2009014679A1 (en) * 2007-07-20 2009-01-29 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Dolasetron trifluoroacetate, polymorphs of dolasetron trifluoroacetate and process for preparation thereof
US20100298397A1 (en) * 2009-05-19 2010-11-25 Singh Nikhilesh N Method of treatment of obsessive compulsive disorder with ondansetron
SI2432467T1 (en) 2009-05-20 2018-06-29 Inserm (Institut National De La Sante Et De La Recherche Medicale) ANTAGONIST RECEPTOR SEROTONINA 5-HT3 FOR THE USE IN THE TREATMENT OF LEASE VESTIBULAR DISEASES
ES2432618T3 (es) 2009-05-20 2013-12-04 Inserm (Institut National De La Santé Et De La Recherche Medicale) Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1220141A (en) * 1981-06-13 1987-04-07 John R. Fozard Treatment of migraine with tropyl benzoate derivatives
US4585866A (en) * 1982-06-09 1986-04-29 Merrell Dow Pharmaceuticals Inc. Treatment of migraine with substituted tropyl benzoate derivatives
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
GB2131420B (en) * 1982-12-03 1986-01-02 Merrell Toraude & Co Tropyl and pseudotropyl alkyl-benzoates and their use in migraine treatment
GB2132189B (en) * 1982-12-10 1986-02-05 Merrell Toraude & Co Tropyl and pseudotropyl benzoates and their use in migraine treatment
GB2131794B (en) * 1982-12-10 1986-04-03 Merrell Toraude & Co Treatment of migraine with n-alkyl-piperidinyl benzoate derivatives
US4713380A (en) * 1985-01-16 1987-12-15 Aldrich-Boranes, Inc. Production of optically pure organoboranes

Also Published As

Publication number Publication date
US4906755A (en) 1990-03-06

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