MX428411B - Compuestos para tratar la disautonomía familiar - Google Patents

Compuestos para tratar la disautonomía familiar

Info

Publication number
MX428411B
MX428411B MX2022007094A MX2022007094A MX428411B MX 428411 B MX428411 B MX 428411B MX 2022007094 A MX2022007094 A MX 2022007094A MX 2022007094 A MX2022007094 A MX 2022007094A MX 428411 B MX428411 B MX 428411B
Authority
MX
Mexico
Prior art keywords
compounds
familial dysautonomia
treating familial
treating
description relates
Prior art date
Application number
MX2022007094A
Other languages
English (en)
Spanish (es)
Other versions
MX2022007094A (es
Inventor
Amal Dakka
Anthony Turpoff
Christie Morrill
Gary Mitchell Karp
Jana Narasimhan
Jiashi Wang
Michael A Arnold
Nanjing Zhang
Nikolai A Naryshkin
Tom Tuan Luong
Xiaoyan Zhang
Original Assignee
Ptc Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ptc Therapeutics Inc filed Critical Ptc Therapeutics Inc
Publication of MX2022007094A publication Critical patent/MX2022007094A/es
Publication of MX428411B publication Critical patent/MX428411B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
MX2022007094A 2019-12-12 2020-12-07 Compuestos para tratar la disautonomía familiar MX428411B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962947049P 2019-12-12 2019-12-12
PCT/US2020/063612 WO2021118929A1 (en) 2019-12-12 2020-12-07 Compounds for treating familial dysautonomia

Publications (2)

Publication Number Publication Date
MX2022007094A MX2022007094A (es) 2022-07-11
MX428411B true MX428411B (es) 2025-11-13

Family

ID=74046197

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022007094A MX428411B (es) 2019-12-12 2020-12-07 Compuestos para tratar la disautonomía familiar

Country Status (14)

Country Link
US (1) US20230057568A1 (enExample)
EP (1) EP4072677A1 (enExample)
JP (2) JP2023506488A (enExample)
KR (1) KR20220113700A (enExample)
CN (1) CN115209955A (enExample)
AU (1) AU2020402717A1 (enExample)
BR (1) BR112022011364A2 (enExample)
CA (1) CA3160053A1 (enExample)
CL (1) CL2022001523A1 (enExample)
CO (1) CO2022008195A2 (enExample)
IL (1) IL293764A (enExample)
MX (1) MX428411B (enExample)
PE (1) PE20221581A1 (enExample)
WO (1) WO2021118929A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020222881C1 (en) 2019-02-13 2026-01-22 Ptc Therapeutics, Inc. Thioeno(3,2-b) pyridin-7-amine compounds for treating familial dysautonomia
WO2020167624A1 (en) 2019-02-13 2020-08-20 Ptc Therapeutics, Inc. Pyrrolo[2,3-d]pyrimidine compounds for treating familial dysautonomia
JP2024533264A (ja) * 2021-09-07 2024-09-12 ピーティーシー セラピューティクス, インコーポレイテッド 神経原性疾患を処置するための方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK6652000A3 (en) * 1997-11-11 2002-05-09 Pfizer Prod Inc Thienopyrimidine and thienopyridine derivatives useful as anticancer agents
WO2005007083A2 (en) * 2003-06-18 2005-01-27 Smithkline Beecham Corporation Chemical compounds
JP2009007341A (ja) * 2007-06-01 2009-01-15 Mitsubishi Tanabe Pharma Corp 医薬組成物
EP2014663A1 (de) * 2007-07-12 2009-01-14 Bayer Schering Pharma AG Thienopyrimidylamine als Modulatoren des EP2-Rezeptors
US20130317045A1 (en) * 2010-09-01 2013-11-28 Ambit Biosciences Corporation Thienopyridine and thienopyrimidine compounds and methods of use thereof
CN103242341B (zh) * 2013-04-19 2015-12-09 中国科学院广州生物医药与健康研究院 噻吩并2,4取代嘧啶类化合物及其药物组合物与应用
CA3199430A1 (en) * 2015-01-16 2016-07-21 The General Hospital Corporation Compounds for improving mrna splicing
GB201700814D0 (en) * 2017-01-17 2017-03-01 Liverpool School Tropical Medicine Compounds
CN110312528B (zh) * 2017-02-20 2022-02-18 国立大学法人京都大学 用于起因于剪接异常的遗传性疾病的药物组合物及治疗方法
AU2020222881C1 (en) * 2019-02-13 2026-01-22 Ptc Therapeutics, Inc. Thioeno(3,2-b) pyridin-7-amine compounds for treating familial dysautonomia
WO2020167624A1 (en) * 2019-02-13 2020-08-20 Ptc Therapeutics, Inc. Pyrrolo[2,3-d]pyrimidine compounds for treating familial dysautonomia

Also Published As

Publication number Publication date
KR20220113700A (ko) 2022-08-16
CO2022008195A2 (es) 2022-07-29
CL2022001523A1 (es) 2023-03-31
BR112022011364A2 (pt) 2022-08-23
US20230057568A1 (en) 2023-02-23
EP4072677A1 (en) 2022-10-19
PE20221581A1 (es) 2022-10-06
MX2022007094A (es) 2022-07-11
AU2020402717A1 (en) 2022-06-23
CN115209955A (zh) 2022-10-18
WO2021118929A1 (en) 2021-06-17
JP2023506488A (ja) 2023-02-16
JP2025133750A (ja) 2025-09-11
CA3160053A1 (en) 2021-06-17
IL293764A (en) 2022-08-01