MX394670B - Agentes anticancerigenos y preparacion de los mismos. - Google Patents

Agentes anticancerigenos y preparacion de los mismos.

Info

Publication number
MX394670B
MX394670B MX2019003368A MX2019003368A MX394670B MX 394670 B MX394670 B MX 394670B MX 2019003368 A MX2019003368 A MX 2019003368A MX 2019003368 A MX2019003368 A MX 2019003368A MX 394670 B MX394670 B MX 394670B
Authority
MX
Mexico
Prior art keywords
preparation
anticancer agents
compounds
methods
family
Prior art date
Application number
MX2019003368A
Other languages
English (en)
Spanish (es)
Other versions
MX2019003368A (es
Inventor
Arun K Ghosh
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of MX2019003368A publication Critical patent/MX2019003368A/es
Publication of MX394670B publication Critical patent/MX394670B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/695Silicon compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14Nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MX2019003368A 2016-09-23 2017-09-22 Agentes anticancerigenos y preparacion de los mismos. MX394670B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662398783P 2016-09-23 2016-09-23
PCT/US2017/052967 WO2018057897A1 (en) 2016-09-23 2017-09-22 Anti-cancer agents and preparation thereof

Publications (2)

Publication Number Publication Date
MX2019003368A MX2019003368A (es) 2019-09-16
MX394670B true MX394670B (es) 2025-03-11

Family

ID=61690726

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019003368A MX394670B (es) 2016-09-23 2017-09-22 Agentes anticancerigenos y preparacion de los mismos.

Country Status (14)

Country Link
US (2) US10858371B2 (enExample)
EP (1) EP3515492B1 (enExample)
JP (1) JP7111722B2 (enExample)
KR (1) KR102646702B1 (enExample)
CN (1) CN109862916A (enExample)
AU (1) AU2017331260B2 (enExample)
BR (1) BR112019005885A2 (enExample)
CA (1) CA3037883A1 (enExample)
DK (1) DK3515492T3 (enExample)
IL (1) IL265521B2 (enExample)
MA (1) MA46291A (enExample)
MX (1) MX394670B (enExample)
RU (1) RU2019111768A (enExample)
WO (1) WO2018057897A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11851441B2 (en) 2016-09-23 2023-12-26 Purdue Research Foundation Anti-cancer agents and preparation thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR901464A (fr) 1943-01-23 1945-07-27 Boehringer & Soehne Gmbh Procédé d'obtention de vanilline
US7825267B2 (en) 2006-09-08 2010-11-02 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Synthesis of FR901464 and analogs with antitumor activity
WO2009031999A1 (en) 2007-09-07 2009-03-12 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Fr901464 and analogs with antitumor activity and method for their preparation
CN101417934B (zh) * 2007-10-24 2012-04-18 国鼎生物科技股份有限公司 分离自牛樟芝萃取物的化合物
KR20160125535A (ko) 2008-03-18 2016-10-31 제넨테크, 인크. 항-her2 항체-약물 접합체와 화학요법제의 병용물, 및 사용 방법
WO2009155606A1 (en) 2008-06-21 2009-12-23 St. Jude Children's Research Hospital Anticancer compounds and methods of making and using same
US20150025017A1 (en) 2012-02-28 2015-01-22 Fred Hutchinson Cancer Research Center Compositions and methods for treating cancer
CA2890569C (en) 2012-11-05 2019-03-05 Pfizer Inc. Spliceostatin analogs
WO2014100367A1 (en) 2012-12-21 2014-06-26 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Synthesis of fr901464 and analogs with antitumor activity
US20140274979A1 (en) 2013-03-13 2014-09-18 Golden Biotechnology Corporation Method for the treatment of fatty liver disease
CA2955059A1 (en) 2013-07-15 2015-01-22 Bettina PRONETH Spiroquinoxaline derivatives as inhibitors of non-apoptotic regulated cell-death
KR102092569B1 (ko) * 2013-09-17 2020-03-25 엘지디스플레이 주식회사 터치 스크린 일체형 디스플레이 장치와 이의 구동 방법
MX375896B (es) * 2013-11-19 2025-03-07 Purdue Research Foundation Agentes anticancerosos y sus preparaciones.
AU2017277786A1 (en) * 2016-06-08 2019-01-03 William Marsh Rice University Derivatives of Thailanstatin A, methods of treatment and methods of synthesis thereof
CN109862916A (zh) 2016-09-23 2019-06-07 普渡研究基金会 抗癌剂及其制备

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11851441B2 (en) 2016-09-23 2023-12-26 Purdue Research Foundation Anti-cancer agents and preparation thereof

Also Published As

Publication number Publication date
CA3037883A1 (en) 2018-03-29
CN109862916A (zh) 2019-06-07
IL265521B2 (en) 2024-09-01
JP7111722B2 (ja) 2022-08-02
JP2019529563A (ja) 2019-10-17
EP3515492A4 (en) 2020-04-08
KR20190077340A (ko) 2019-07-03
BR112019005885A2 (pt) 2020-06-02
RU2019111768A3 (enExample) 2020-11-24
WO2018057897A1 (en) 2018-03-29
IL265521A (en) 2019-05-30
US11851441B2 (en) 2023-12-26
AU2017331260B2 (en) 2024-11-07
IL265521B1 (en) 2024-05-01
MA46291A (fr) 2019-07-31
RU2019111768A (ru) 2020-10-23
AU2017331260A1 (en) 2019-05-16
US20210395265A1 (en) 2021-12-23
DK3515492T3 (da) 2023-08-28
EP3515492A1 (en) 2019-07-31
MX2019003368A (es) 2019-09-16
US20190218228A1 (en) 2019-07-18
EP3515492B1 (en) 2023-07-26
KR102646702B1 (ko) 2024-03-11
US10858371B2 (en) 2020-12-08

Similar Documents

Publication Publication Date Title
ECSP20033467A (es) Compuestos macrocíclicos para tratar enfermedades
CL2018001685A1 (es) Compuestos heterociclicos como inmuno moduladores.
CL2019000511A1 (es) Inhibidores de procesos metabólicos celulares.
CO2017001994A2 (es) Compuestos activos hacia bromodominios
CL2018001152A1 (es) Composiciones y métodos para el tratamiento del cáncer
SV2017005489A (es) Terapias de combinación para el tratamiento de cánceres
MX2019002750A (es) Derivados de pirazolopiridina como moduladores de cinasa 1 progenitora hematopoyetica (hpk1) y usos de los mismos para tratamiento de cancer.
CL2017002996A1 (es) Compuestos alqueno tetrasustituidos y su uso
CL2016002516A1 (es) “compuestos derivados de espirociclo sustituidos, inhibidores atx; composición farmacéutica que los comprende; y su uso en el tratamiento del cáncer, inflamaciones, dolor neuropático, enfermedades fibróticas, trombosis, entre otros”. pct
UY37435A (es) Pirrolidinas sustituidas y métodos para usarlas
CO2017001493A2 (es) Kits que comprenden inhibidores tigit y agentes anticáncer
CR20150376A (es) Compuestos sustituidos de pirrolopirimidina, compuestos de los mismos y metodos de tratamiento con los mismos
MX2016013457A (es) Inhibidores de mdm2 y metodos terapeuticos que utilizan el mismo.
UY34750A (es) ?compuestos para el tratamiento del hiv, composiciones,métodos de preparación, intermediarios y métodos terapéuticos?.
UY36075A (es) Derivados de tubulisina
GT201500294A (es) Compuestos de biaril-amida como inhibidores de cinasa
MX370664B (es) Inhibidores de la proteína regulada por glucosa 94 (gpr94) selectivos y usos de los mismos.
CL2017000506A1 (es) Nuevos anticuerpos anti-mfi2 y metodos de uso
CL2015002546A1 (es) Derivados 3-fenilpropilamina sustituidos para el tratamiento de enfermedades y trastornos oftálmicos
CR20180228A (es) Terapia adjunta con 25-hidroxi vitamina d y articulos de la misma
CL2016002835A1 (es) “compuestos derivados de pladienolida con un resto piridinico; composición farmacéutica que los comprende; y su uso en el tratamiento del cáncer”. pct
MX2016016583A (es) Derivados de indolizina como inhibidores de fosfoinositido-3 cinasas.
DOP2015000298A (es) Compuestos nuevos para el tratamiento del cáncer
CO2017000950A2 (es) Compuestos que comprenden oligonucleótidos modificados dirigidos a mir-103 y/o mir-107 para trastornos metabólicos
SV2016005293A (es) Compuestos de azol amido-sustituidos como inhibidores de tnks1 y/o tnks2