MX389554B - Formulaciones antihelminticas veterinarias estables. - Google Patents

Formulaciones antihelminticas veterinarias estables.

Info

Publication number
MX389554B
MX389554B MX2016012319A MX2016012319A MX389554B MX 389554 B MX389554 B MX 389554B MX 2016012319 A MX2016012319 A MX 2016012319A MX 2016012319 A MX2016012319 A MX 2016012319A MX 389554 B MX389554 B MX 389554B
Authority
MX
Mexico
Prior art keywords
anthelmintic
actives
methods
stable veterinary
veterinary formulations
Prior art date
Application number
MX2016012319A
Other languages
English (en)
Other versions
MX2016012319A (es
Inventor
Karen Yeritsyan
Original Assignee
Donaghys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Donaghys Ltd filed Critical Donaghys Ltd
Publication of MX2016012319A publication Critical patent/MX2016012319A/es
Publication of MX389554B publication Critical patent/MX389554B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Toxicology (AREA)

Abstract

Se describen en la presente formulaciones veterinarias estables y los métodos de tratamiento y uso, que comprenden al menos una lactona macrocíclica y levamisol como agentes antihelmínticos activos, opcionalmente también con al menos un antihelmíntico de la clase bencimidazol, en donde los ingredientes activos se disuelven juntos en un sistema de solventes que comprende dimetilsulfóxido (DMSO). Las formulaciones veterinarias, métodos y uso de las mismas incluyen la capacidad de suministrar dos o más activos antihelmínticos en la única solución (o suspensión) mientras que también mantengan la estabilidad de la formulación cuando se almacenan durante un período de tiempo. El suministro de diferentes antihelmínticos con diferentes actividades permite que se dirijan a diversas clases de parásitos en una sola dosis.
MX2016012319A 2014-03-24 2015-03-24 Formulaciones antihelminticas veterinarias estables. MX389554B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ622869A NZ622869A (en) 2014-03-24 2014-03-24 Stable veterinary anthelmintic formulations
PCT/NZ2015/000018 WO2015147655A1 (en) 2014-03-24 2015-03-24 Stable veterinary anthelmintic formulations

Publications (2)

Publication Number Publication Date
MX2016012319A MX2016012319A (es) 2017-01-06
MX389554B true MX389554B (es) 2025-03-20

Family

ID=52464905

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016012319A MX389554B (es) 2014-03-24 2015-03-24 Formulaciones antihelminticas veterinarias estables.

Country Status (11)

Country Link
US (1) US10449179B2 (es)
EP (1) EP3122352A4 (es)
CN (1) CN106132409B (es)
AR (1) AR099829A1 (es)
AU (3) AU2015237371A1 (es)
CA (1) CA2942008C (es)
MX (1) MX389554B (es)
NZ (2) NZ701697A (es)
RU (1) RU2711200C2 (es)
UY (1) UY36045A (es)
WO (1) WO2015147655A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018038623A1 (en) * 2016-08-23 2018-03-01 Donaghys Limited Improvements in parasite treatments
EA201992125A1 (ru) 2017-03-17 2020-03-16 КРКА, д.д., НОВО МЕСТО Стабильная ветеринарная композиция для местного применения
WO2020027881A1 (en) 2018-08-03 2020-02-06 Nectero Medical, Inc. Purified pentagalloyl glucose and devices for delivery
JP7199653B2 (ja) * 2018-08-17 2023-01-06 住化エンバイロメンタルサイエンス株式会社 樹脂製容器入り外部寄生虫駆除剤
WO2020198371A1 (en) * 2019-03-26 2020-10-01 Nectero Medical, Inc. Methods and devices for treatment of post-surgery laxity of tendons and tendon repair
CN111840234A (zh) * 2020-08-14 2020-10-30 瑞普（天津）生物药业有限公司 一种兽用复方驱虫颗粒剂及其制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8327761D0 (en) * 1983-10-17 1983-11-16 Janssen Pharmaceutica Nv Parasiticidal formulations
NZ248486A (en) 1993-08-24 1996-07-26 Ashmont Holdings Limited Subst Stable anthelmintic formulation containing closantel and one or more avermectins or milbemycins in a glycol based solvent
DE19654079A1 (de) * 1996-12-23 1998-06-25 Bayer Ag Endo-ekto-parasitizide Mittel
CA2211949A1 (en) * 1997-07-21 1999-01-29 David Farley Johnson Nonaqueous compositions for parenteral administration
NZ508969A (en) 1999-06-04 2002-12-20 Nufarm Ltd Pesticidal emulsion containing levamisole in the aqueous phase and a macrocyclic lactone anthelmintic in the organic phase
NZ515772A (en) 1999-06-04 2002-12-20 Nufarm Ltd Pesticidal emulsion composition containing levamisole in the aqueous phase and an anthelmintic in the organic phase
CA2521268C (en) 2003-04-04 2012-10-16 Merial Ltd. Topical anthelmintic veterinary formulations
NZ535644A (en) 2003-07-25 2007-05-31 Ashmont Holdings Ltd Anthelmintic formulations
JP2009508853A (ja) 2005-09-15 2009-03-05 メリアル リミテッド 駆虫製剤
NZ552040A (en) * 2006-12-13 2009-04-30 Bomac Research Ltd Veterinary formulation comprising an anthelmintic compound and glyceryl acetate
RU2367435C1 (ru) * 2008-03-26 2009-09-20 Александр Анатольевич Смирнов Состав для лечения гельминтозов домашних животных
AR081970A1 (es) 2010-06-24 2012-10-31 Intervet Int Bv Formulacion inyectable de una lactona macrociclica y levamisol, formulacion y uso veterinario
NZ594610A (en) * 2011-08-16 2013-03-28 Virbac New Zealand Ltd Injectable Anthelmintic Formulations cotaining levamisole and one or more macrocyclic lactones for controlling internal parasites in ruminants
WO2013043064A1 (en) * 2011-09-23 2013-03-28 Alleva Animal Health Limited Veterinary anthelmintic delivery system

Also Published As

Publication number Publication date
AR099829A1 (es) 2016-08-24
WO2015147655A1 (en) 2015-10-01
CN106132409A (zh) 2016-11-16
AU2022252717A1 (en) 2022-11-03
NZ622869A (en) 2015-01-30
RU2016140272A3 (es) 2018-09-26
AU2015237371A1 (en) 2016-09-15
CA2942008A1 (en) 2015-10-01
AU2020227063A1 (en) 2020-09-24
CA2942008C (en) 2022-06-21
US10449179B2 (en) 2019-10-22
MX2016012319A (es) 2017-01-06
RU2711200C2 (ru) 2020-01-15
CN106132409B (zh) 2020-09-01
AU2022252717B2 (en) 2024-09-05
UY36045A (es) 2015-07-31
US20170007584A1 (en) 2017-01-12
EP3122352A1 (en) 2017-02-01
RU2016140272A (ru) 2018-04-24
EP3122352A4 (en) 2017-11-01
NZ701697A (en) 2016-05-27

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