MX374659B - Ligandos macrocíclicos con uno o varios grupos picolinato, sus complejos así como sus utilizaciones médicas. - Google Patents

Ligandos macrocíclicos con uno o varios grupos picolinato, sus complejos así como sus utilizaciones médicas.

Info

Publication number
MX374659B
MX374659B MX2018007739A MX2018007739A MX374659B MX 374659 B MX374659 B MX 374659B MX 2018007739 A MX2018007739 A MX 2018007739A MX 2018007739 A MX2018007739 A MX 2018007739A MX 374659 B MX374659 B MX 374659B
Authority
MX
Mexico
Prior art keywords
sub
picolinate
complexes
group
groups
Prior art date
Application number
MX2018007739A
Other languages
English (en)
Other versions
MX2018007739A (es
Inventor
Fur Mariane Le
Maryline Beyler
Olivier Rousseaux
Raphaël Tripier
Original Assignee
Guerbet Sa
Centre Nat Rech Scient
Univ Bretagne Occidentale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet Sa, Centre Nat Rech Scient, Univ Bretagne Occidentale filed Critical Guerbet Sa
Publication of MX2018007739A publication Critical patent/MX2018007739A/es
Publication of MX374659B publication Critical patent/MX374659B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a nuevos ligandos macrocíclicos sustituidos por al menos un grupo picolinato, así como sus complejos reactivos y sus utilizaciones en imagenología médica y/o en terapia, concretamente en radiología intervencionista. La presente invención también se refiere a un nuevo procedimiento de preparación de ligandos tales como de acuerdo con la invención, así como sus intermedios de preparación.
MX2018007739A 2015-12-24 2016-12-23 Ligandos macrocíclicos con uno o varios grupos picolinato, sus complejos así como sus utilizaciones médicas. MX374659B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1563346A FR3046172B1 (fr) 2015-12-24 2015-12-24 Ligands macrocycliques avec groupement(s) picolinate(s), leurs complexes ainsi que leurs utilisations medicales
PCT/EP2016/082644 WO2017109217A1 (fr) 2015-12-24 2016-12-23 Ligands macrocycliques avec groupement(s) picolinate(s), leurs complexes ainsi que leurs utilisations médicales

Publications (2)

Publication Number Publication Date
MX2018007739A MX2018007739A (es) 2018-11-09
MX374659B true MX374659B (es) 2025-03-06

Family

ID=55451418

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018007739A MX374659B (es) 2015-12-24 2016-12-23 Ligandos macrocíclicos con uno o varios grupos picolinato, sus complejos así como sus utilizaciones médicas.

Country Status (14)

Country Link
US (2) US10711001B2 (es)
EP (1) EP3394063B1 (es)
JP (1) JP6813151B2 (es)
KR (1) KR102779124B1 (es)
CN (1) CN108884095B (es)
AU (1) AU2016375192B2 (es)
BR (1) BR112018012939B1 (es)
CA (1) CA3008913C (es)
ES (1) ES2760957T3 (es)
FR (1) FR3046172B1 (es)
MX (1) MX374659B (es)
PL (1) PL3394063T3 (es)
PT (1) PT3394063T (es)
WO (1) WO2017109217A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9721551B2 (en) 2015-09-29 2017-08-01 Amper Music, Inc. Machines, systems, processes for automated music composition and generation employing linguistic and/or graphical icon based musical experience descriptions
FR3068355B1 (fr) * 2017-06-28 2020-12-11 Guerbet Sa Ligands macrocycliques renforces, leurs complexes ainsi que leurs utilisations
WO2019185901A1 (en) 2018-03-30 2019-10-03 Centre National De La Recherche Scientifique Pyclen-based macrocyclic ligands, chelates thereof and uses thereof
US11037538B2 (en) 2019-10-15 2021-06-15 Shutterstock, Inc. Method of and system for automated musical arrangement and musical instrument performance style transformation supported within an automated music performance system
US11024275B2 (en) 2019-10-15 2021-06-01 Shutterstock, Inc. Method of digitally performing a music composition using virtual musical instruments having performance logic executing within a virtual musical instrument (VMI) library management system
US10964299B1 (en) 2019-10-15 2021-03-30 Shutterstock, Inc. Method of and system for automatically generating digital performances of music compositions using notes selected from virtual musical instruments based on the music-theoretic states of the music compositions
ES2979354T3 (es) 2021-07-30 2024-09-25 Guerbet Sa Ligandos macrocíclicos con grupos picolinato(s), sus complejos y sus usos médicos
JP2024125438A (ja) * 2021-08-03 2024-09-19 住友化学株式会社 放射性金属錯体及びその製造方法、並びに放射性金属捕捉剤
CN116554172A (zh) * 2023-05-18 2023-08-08 国科温州研究院(温州生物材料与工程研究所) Pyclen配体、Pyclen配合物及制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2644785B1 (fr) * 1989-03-24 1991-07-05 Guerbet Sa Nouveaux ligands macrocycliques azotes, procede de preparation, complexes metalliques formes par ces ligands et composition de diagnostic les contenant
EP1369134A1 (en) * 2002-06-05 2003-12-10 Bracco Imaging S.p.A. New agents for magnetic imaging method
WO2006020779A2 (en) * 2004-08-10 2006-02-23 Dow Global Technologies Inc. Targeting chelants and chelates
FR2875410B1 (fr) * 2004-09-23 2012-11-16 Guerbet Sa Composes de diagnostique pour le ciblage de recpteur a chimiokines
FR3006688B1 (fr) * 2013-06-06 2015-08-14 Centre Nat Rech Scient Chelates du plomb (ii) et du bismuth (iii) a base de tetraazacycloalcanes trans-di-n-picolinates

Also Published As

Publication number Publication date
BR112018012939A2 (pt) 2018-12-11
AU2016375192A1 (en) 2018-07-12
FR3046172B1 (fr) 2019-05-31
ES2760957T3 (es) 2020-05-18
JP2019508482A (ja) 2019-03-28
JP6813151B2 (ja) 2021-01-13
EP3394063B1 (fr) 2019-10-02
FR3046172A1 (fr) 2017-06-30
CN108884095B (zh) 2021-07-16
AU2016375192A2 (en) 2018-09-20
BR112018012939B1 (pt) 2023-01-17
MX2018007739A (es) 2018-11-09
US10711001B2 (en) 2020-07-14
EP3394063A1 (fr) 2018-10-31
PL3394063T3 (pl) 2020-06-29
AU2016375192B2 (en) 2020-06-11
CN108884095A (zh) 2018-11-23
US10981912B2 (en) 2021-04-20
PT3394063T (pt) 2020-01-03
CA3008913A1 (fr) 2017-06-29
KR102779124B1 (ko) 2025-03-12
US20190023705A1 (en) 2019-01-24
WO2017109217A1 (fr) 2017-06-29
KR20180117594A (ko) 2018-10-29
CA3008913C (fr) 2023-10-17
US20200123155A1 (en) 2020-04-23

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