MX362515B - Proteinas péptidos y métodos de uso de las plantas antifúngicas. - Google Patents
Proteinas péptidos y métodos de uso de las plantas antifúngicas.Info
- Publication number
- MX362515B MX362515B MX2015015071A MX2015015071A MX362515B MX 362515 B MX362515 B MX 362515B MX 2015015071 A MX2015015071 A MX 2015015071A MX 2015015071 A MX2015015071 A MX 2015015071A MX 362515 B MX362515 B MX 362515B
- Authority
- MX
- Mexico
- Prior art keywords
- molecules
- methods
- plants
- peptides
- well
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/20—Fabaceae or Leguminosae [Pea or Legume family], e.g. pea, lentil, soybean, clover, acacia, honey locust, derris or millettia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8282—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Environmental Sciences (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Developmental Biology & Embryology (AREA)
- Physiology (AREA)
- Mycology (AREA)
- Pest Control & Pesticides (AREA)
- Oncology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Abstract
La presente invención se refiere a plantas transgénicas que expresan proteínas y péptidos antifungicos de MtDef5 que exhiben altos niveles de resistencia a los hongos susceptibles. Tales plantas transgénicas contienen una construcción de ADN recombinante que comprende una secuencia de péptido de señal natural o heteróloga enlazada operablemente a una secuencia de ácido nucleico que codifica estas moléculas. También se proporciona métodos para producir tales plantas, métodos para proteger a las plantas contra infecciones y daño fúngico susceptible, así como composiciones que se pueden aplicar a los lugares de las plantas, que comprenden microorganismos que expresan estas moléculas, o estas moléculas mismas, así como composiciones farmacéuticas que contienen estas moléculas. También están incluidos por la invención el uso humano y veterinario de las proteínas antifúngicas de MtDef5 y péptidos para tratar las infecciones susceptibles.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361817415P | 2013-04-30 | 2013-04-30 | |
PCT/US2014/035786 WO2014179260A2 (en) | 2013-04-30 | 2014-04-29 | Antifungal plant proteins, peptides, and methods of use |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015015071A MX2015015071A (es) | 2016-07-07 |
MX362515B true MX362515B (es) | 2019-01-22 |
Family
ID=51844092
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015015071A MX362515B (es) | 2013-04-30 | 2014-04-29 | Proteinas péptidos y métodos de uso de las plantas antifúngicas. |
MX2018010353A MX2018010353A (es) | 2013-04-30 | 2015-10-28 | Proteinas, peptidos de planta antifungicos y metodos de uso. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018010353A MX2018010353A (es) | 2013-04-30 | 2015-10-28 | Proteinas, peptidos de planta antifungicos y metodos de uso. |
Country Status (11)
Country | Link |
---|---|
US (4) | US10253328B2 (es) |
EP (2) | EP2999712B1 (es) |
JP (1) | JP6440687B2 (es) |
KR (1) | KR101957550B1 (es) |
CN (1) | CN105658663A (es) |
AU (1) | AU2014260123B2 (es) |
BR (1) | BR112015027572A2 (es) |
CA (1) | CA2910745A1 (es) |
MX (2) | MX362515B (es) |
WO (1) | WO2014179260A2 (es) |
ZA (1) | ZA201508661B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20190194268A1 (en) * | 2016-03-11 | 2019-06-27 | Donald Danforth Plant Science Center | Multimeric defensin proteins and related methods |
CN107988301B (zh) * | 2018-01-11 | 2021-04-27 | 中国科学院新疆理化技术研究所 | 一种鹰嘴豆豆瓣多肽的制备方法及其应用 |
US20220089661A1 (en) * | 2019-01-07 | 2022-03-24 | Donald Danforth Plant Science Center | Antimicrobial peptides |
CN110272908B (zh) * | 2019-07-11 | 2021-02-09 | 太极集团有限公司 | 粉棒束孢Kill Protion4基因、重组蛋白及应用 |
CN112341287A (zh) * | 2019-08-09 | 2021-02-09 | 马万龙 | 一种植物生长调理剂、其制备方法和用途 |
CN115873824B (zh) * | 2022-10-18 | 2023-07-28 | 扬州大学 | 水稻rsb11基因在抗纹枯病中的应用 |
WO2024137918A1 (en) | 2022-12-21 | 2024-06-27 | Donald Danforth Plant Science Center | Antimicrobial peptides and modifications thereof |
Family Cites Families (36)
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US4196265A (en) | 1977-06-15 | 1980-04-01 | The Wistar Institute | Method of producing antibodies |
US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
US4943529A (en) | 1982-05-19 | 1990-07-24 | Gist-Brocades Nv | Kluyveromyces as a host strain |
US4546082A (en) | 1982-06-17 | 1985-10-08 | Regents Of The Univ. Of California | E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins |
US4588684A (en) | 1983-04-26 | 1986-05-13 | Chiron Corporation | a-Factor and its processing signals |
US4870008A (en) | 1983-08-12 | 1989-09-26 | Chiron Corporation | Secretory expression in eukaryotes |
US5741672A (en) | 1984-07-27 | 1998-04-21 | Unilever Patent Holdings B.V. | Expression and production of polypeptides using the promoters of the hansenula polymorpha MOX and DAS genes |
US4855231A (en) | 1984-10-30 | 1989-08-08 | Phillips Petroleum Company | Regulatory region for heterologous gene expression in yeast |
AU590558B2 (en) | 1985-04-30 | 1989-11-09 | Monsanto Company | Plant-colonizing microorganisms containing the toxin gene of b. thuringiensis as a chromosomal insertion |
US5004863B2 (en) | 1986-12-03 | 2000-10-17 | Agracetus | Genetic engineering of cotton plants and lines |
ATE105858T1 (de) | 1987-07-17 | 1994-06-15 | Rhein Biotech Ges Fuer Biotech | Dna-moleküle, die für fmdh-kontrollabschnitte und strukturgene für ein protein mit fmdh-aktivität kodieren, sowie deren anwendung. |
CA1340772C (en) | 1987-12-30 | 1999-09-28 | Patricia Tekamp-Olson | Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences |
JP3364616B2 (ja) | 1989-02-24 | 2003-01-08 | モンサント テクノロジー エルエルシー | 合成植物遺伝子と調製方法 |
EP0392225B1 (en) | 1989-03-24 | 2003-05-28 | Syngenta Participations AG | Disease-resistant transgenic plants |
EP0426641B1 (en) | 1989-10-31 | 2000-09-13 | Monsanto Company | Promoter for transgenic plants |
ES2071319T3 (es) | 1990-06-15 | 1995-06-16 | Hoechst Schering Agrevo Gmbh | Polipeptido antifungico, procedimiento para su preparacion. |
AU655197B2 (en) | 1990-06-25 | 1994-12-08 | Monsanto Technology Llc | Glyphosate tolerant plants |
US5459252A (en) | 1991-01-31 | 1995-10-17 | North Carolina State University | Root specific gene promoter |
JP3605411B2 (ja) | 1991-05-15 | 2004-12-22 | モンサント・カンパニー | 形質転換された稲植物の製法 |
US5538525A (en) | 1991-08-29 | 1996-07-23 | Zeneca Limited | Biocidal proteins |
US5593874A (en) | 1992-03-19 | 1997-01-14 | Monsanto Company | Enhanced expression in plants |
US5689052A (en) | 1993-12-22 | 1997-11-18 | Monsanto Company | Synthetic DNA sequences having enhanced expression in monocotyledonous plants and method for preparation thereof |
AUPN283495A0 (en) | 1995-05-05 | 1995-06-01 | Australian National University, The | Plant promoter activated by fungal infection |
US5837876A (en) | 1995-07-28 | 1998-11-17 | North Carolina State University | Root cortex specific gene promoter |
US6121436A (en) | 1996-12-13 | 2000-09-19 | Monsanto Company | Antifungal polypeptide and methods for controlling plant pathogenic fungi |
US6972197B1 (en) | 1999-03-18 | 2005-12-06 | The University Of Chicago | Plant chromosome compositions and methods |
US7102055B1 (en) | 1997-11-18 | 2006-09-05 | Pioneer Hi-Bred International, Inc. | Compositions and methods for the targeted insertion of a nucleotide sequence of interest into the genome of a plant |
WO2000042207A2 (en) | 1999-01-14 | 2000-07-20 | Monsanto Technology Llc | Soybean transformation method |
US6596925B1 (en) | 1999-03-25 | 2003-07-22 | Genesis Research & Development Corp. Ltd. | Compositions and methods for the modification of gene expression |
US7572635B2 (en) | 2004-06-25 | 2009-08-11 | Monsanto Technology Llc | Method for agrobacterium transformation for dihaploid corn plants |
US7273965B2 (en) * | 2004-06-30 | 2007-09-25 | Pioneer Hi-Bred International, Inc. | Methods of protecting plants from pathogenic fungi |
US7825297B2 (en) | 2006-12-22 | 2010-11-02 | Donald Danforth Plant Science Center | Expression of antifungal plant proteins in transgenic plants |
AU2008241364B2 (en) * | 2007-04-20 | 2013-03-21 | Hexima Limited | Modified plant defensin |
AR075257A1 (es) | 2008-02-01 | 2011-03-23 | Hexima Ltd | Sistema de proteccion de plantas contra la infeccion por agentes patogenos |
US20120108422A1 (en) * | 2009-06-18 | 2012-05-03 | Basf Se | Antifungal 1,2,4-triazolyl Derivatives |
AU2011282167A1 (en) * | 2010-07-20 | 2013-03-07 | Donald Danforth Plant & Science Center | Transgenic plants expressing a viral antifungal protein |
-
2014
- 2014-04-29 WO PCT/US2014/035786 patent/WO2014179260A2/en active Application Filing
- 2014-04-29 CA CA2910745A patent/CA2910745A1/en not_active Abandoned
- 2014-04-29 BR BR112015027572A patent/BR112015027572A2/pt not_active Application Discontinuation
- 2014-04-29 EP EP14792240.5A patent/EP2999712B1/en not_active Not-in-force
- 2014-04-29 KR KR1020157033839A patent/KR101957550B1/ko active IP Right Grant
- 2014-04-29 CN CN201480034810.7A patent/CN105658663A/zh active Pending
- 2014-04-29 JP JP2016511792A patent/JP6440687B2/ja not_active Expired - Fee Related
- 2014-04-29 MX MX2015015071A patent/MX362515B/es active IP Right Grant
- 2014-04-29 US US14/888,011 patent/US10253328B2/en active Active
- 2014-04-29 AU AU2014260123A patent/AU2014260123B2/en not_active Ceased
- 2014-04-29 EP EP18206999.7A patent/EP3536702A1/en not_active Withdrawn
-
2015
- 2015-10-28 MX MX2018010353A patent/MX2018010353A/es unknown
- 2015-11-25 ZA ZA2015/08661A patent/ZA201508661B/en unknown
-
2019
- 2019-02-15 US US16/277,157 patent/US20190169633A1/en not_active Abandoned
-
2021
- 2021-06-15 US US17/304,156 patent/US20210317470A1/en not_active Abandoned
-
2023
- 2023-06-16 US US18/336,772 patent/US20230392161A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN105658663A (zh) | 2016-06-08 |
CA2910745A1 (en) | 2014-11-06 |
EP3536702A1 (en) | 2019-09-11 |
MX2018010353A (es) | 2022-01-25 |
KR101957550B1 (ko) | 2019-06-28 |
US20210317470A1 (en) | 2021-10-14 |
JP2016525877A (ja) | 2016-09-01 |
US20190169633A1 (en) | 2019-06-06 |
WO2014179260A3 (en) | 2016-02-25 |
KR20160003163A (ko) | 2016-01-08 |
WO2014179260A2 (en) | 2014-11-06 |
US20230392161A1 (en) | 2023-12-07 |
EP2999712A4 (en) | 2017-01-11 |
EP2999712A2 (en) | 2016-03-30 |
EP2999712B1 (en) | 2018-11-21 |
JP6440687B2 (ja) | 2018-12-19 |
AU2014260123B2 (en) | 2018-10-11 |
US10253328B2 (en) | 2019-04-09 |
BR112015027572A2 (pt) | 2018-03-27 |
MX2015015071A (es) | 2016-07-07 |
AU2014260123A1 (en) | 2015-12-03 |
US20160208278A1 (en) | 2016-07-21 |
ZA201508661B (en) | 2017-04-26 |
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Legal Events
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FG | Grant or registration |