MX358789B - Moleculas bioconjugadas con actividades biologicas y tecnofuncionales, su proceso de obtencion y usos. - Google Patents

Moleculas bioconjugadas con actividades biologicas y tecnofuncionales, su proceso de obtencion y usos.

Info

Publication number
MX358789B
MX358789B MX2013015020A MX2013015020A MX358789B MX 358789 B MX358789 B MX 358789B MX 2013015020 A MX2013015020 A MX 2013015020A MX 2013015020 A MX2013015020 A MX 2013015020A MX 358789 B MX358789 B MX 358789B
Authority
MX
Mexico
Prior art keywords
molecules
techno
biological
production
bioconjugate
Prior art date
Application number
MX2013015020A
Other languages
English (en)
Other versions
MX2013015020A (es
Inventor
Javier Placido Arrizon Gaviño Dr
Marisela Gonzalez Avila Dra
Eduardo Padilla Camberos Dr
Georgina Coral Sandoval Fabian Dra
Moises Martinez Velazquez Dr
Socorro Josefina Villanueva Rodriguez Dra
Leticia Casas Godoy Dra
MARTÍNEZ VELÁZQUEZ Moisés
Padilla Camberos Eduardo
Coral SANDOVAL FABIÁN Georgina
Plácido Arrizon Gaviño Javier
González Ávila Marisela
Josefina VILLANUEVA RODRÍGUEZ Socorro
Casas Godoy Leticia
Original Assignee
Centro De Investig Y Asistencia En Tecnologia Y Diseno Del Estado De Jalisco A C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro De Investig Y Asistencia En Tecnologia Y Diseno Del Estado De Jalisco A C filed Critical Centro De Investig Y Asistencia En Tecnologia Y Diseno Del Estado De Jalisco A C
Priority to MX2013015020A priority Critical patent/MX358789B/es
Priority to US15/104,421 priority patent/US20160310602A1/en
Priority to EP14871834.9A priority patent/EP3085702A4/en
Priority to PCT/MX2014/000013 priority patent/WO2015093929A1/es
Publication of MX2013015020A publication Critical patent/MX2013015020A/es
Priority to US15/797,486 priority patent/US20180110869A1/en
Publication of MX358789B publication Critical patent/MX358789B/es
Priority to US16/355,949 priority patent/US20190275163A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0051—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Fructofuranans, e.g. beta-2,6-D-fructofuranan, i.e. levan; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Materials Engineering (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

La presente invención se refiere a la síntesis de moléculas bioconjugadas, de entre dos o más grupos funcionales siguientes: azúcares, prebióticos, oligosacáridos, polisacáridos, triglicéridos, ácidos grasos, ésteres de ácidos grasos, antiinflamatorios; con su proceso de obtención por síntesis biocatalizada utilizando hidrolasas tales como esterasa, proteasa lipasa o cutinasa y a su purificación por diversos métodos que comprenden lavado y secado. Así como a sus usos en alimentos, fármacos y cosméticos: como nutracéutico prebiótico, antiinflamatorio, antitumoral, vector intestinal, ingrediente tecnofuncional para uso alimenticio (emulsificante, sustituto de grasa) y cosmético emoliente; los cuales son posibles al tratarse de moléculas no tóxicas de acuerdo a las pruebas Ames.
MX2013015020A 2013-12-18 2013-12-18 Moleculas bioconjugadas con actividades biologicas y tecnofuncionales, su proceso de obtencion y usos. MX358789B (es)

Priority Applications (6)

Application Number Priority Date Filing Date Title
MX2013015020A MX358789B (es) 2013-12-18 2013-12-18 Moleculas bioconjugadas con actividades biologicas y tecnofuncionales, su proceso de obtencion y usos.
US15/104,421 US20160310602A1 (en) 2013-12-18 2014-01-17 Bioconjugate molecules with biological and techno-functional activity, method for the production thereof and use thereof
EP14871834.9A EP3085702A4 (en) 2013-12-18 2014-01-17 BIOKONJUGATMOLEKÜLE WITH BIOLOGICAL AND TECHNOFUNCTIONAL ACTIVITY, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF
PCT/MX2014/000013 WO2015093929A1 (es) 2013-12-18 2014-01-17 Moléculas bioconjugadas con actividades biológicas y tecnofuncionales, su proceso de obtención y usos
US15/797,486 US20180110869A1 (en) 2013-12-18 2017-10-30 Bioconjugate molecules with biological and techno-functional activity, method for the production thereof and use thereof
US16/355,949 US20190275163A1 (en) 2013-12-18 2019-03-18 Bioconjugate molecules with biological and techno-functional activity, method for the production thereof and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2013015020A MX358789B (es) 2013-12-18 2013-12-18 Moleculas bioconjugadas con actividades biologicas y tecnofuncionales, su proceso de obtencion y usos.

Publications (2)

Publication Number Publication Date
MX2013015020A MX2013015020A (es) 2015-06-17
MX358789B true MX358789B (es) 2018-08-20

Family

ID=53403171

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013015020A MX358789B (es) 2013-12-18 2013-12-18 Moleculas bioconjugadas con actividades biologicas y tecnofuncionales, su proceso de obtencion y usos.

Country Status (4)

Country Link
US (3) US20160310602A1 (es)
EP (1) EP3085702A4 (es)
MX (1) MX358789B (es)
WO (1) WO2015093929A1 (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4614718A (en) * 1983-08-23 1986-09-30 Dai-Ichio Kogyo Seiyaku Co., Ltd. Synthesis of sugar or sugar-alcohol fatty acid esters
JPH03168091A (ja) * 1989-11-27 1991-07-19 Lion Corp 糖脂肪酸エステルの製造方法
EP1600060A1 (en) * 2004-05-25 2005-11-30 Cognis IP Management GmbH Oral and/or topical compositions comprising prebiotics and fatty acid
WO2009078030A1 (en) * 2007-12-17 2009-06-25 Alkem Laboratories Limited Fat substitute

Also Published As

Publication number Publication date
MX2013015020A (es) 2015-06-17
US20180110869A1 (en) 2018-04-26
WO2015093929A1 (es) 2015-06-25
EP3085702A1 (en) 2016-10-26
EP3085702A4 (en) 2016-11-30
US20190275163A1 (en) 2019-09-12
US20160310602A1 (en) 2016-10-27

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