MX356789B - Composición de difenidol de liberación prolongada. - Google Patents
Composición de difenidol de liberación prolongada.Info
- Publication number
- MX356789B MX356789B MX2013000662A MX2013000662A MX356789B MX 356789 B MX356789 B MX 356789B MX 2013000662 A MX2013000662 A MX 2013000662A MX 2013000662 A MX2013000662 A MX 2013000662A MX 356789 B MX356789 B MX 356789B
- Authority
- MX
- Mexico
- Prior art keywords
- prolonged
- composition
- release
- diphenidol
- release diphenidol
- Prior art date
Links
- 229960003520 diphenidol Drugs 0.000 title abstract 2
- OGAKLTJNUQRZJU-UHFFFAOYSA-N diphenidol Chemical compound C=1C=CC=CC=1C(C=1C=CC=CC=1)(O)CCCN1CCCCC1 OGAKLTJNUQRZJU-UHFFFAOYSA-N 0.000 title abstract 2
- 230000002035 prolonged effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- AVZIYZHXZAYGJS-UHFFFAOYSA-N Difenidol hydrochloride Chemical compound Cl.C=1C=CC=CC=1C(C=1C=CC=CC=1)(O)CCCN1CCCCC1 AVZIYZHXZAYGJS-UHFFFAOYSA-N 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 229960005058 diphenidol hydrochloride Drugs 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describe una composición farmacéutica de difenidol de liberación prolongada que comprende: a) de 15 a 50% de clorhidrato de difenidol; b) de 0.1 a 20% de uno o más agentes aglutinantes; c) de 5 a 90% de uno o más agentes diluentes; d) de 5 a 50% de uno o más agentes modificadores de la liberación; e) de 0.25 a 10% de uno o más agentes lubricantes; y f) 0.1 a 10% de agentes deslizantes. De manera preferida, esta composición farmacéutica se administra por vía oral y se encuentra en forma de tableta.
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2013000662A MX356789B (es) | 2013-01-16 | 2013-01-16 | Composición de difenidol de liberación prolongada. |
| PE2015000603A PE20150888A1 (es) | 2013-01-16 | 2014-01-15 | Composicion de difenidol de liberacion prolongada |
| US14/759,683 US10188610B2 (en) | 2013-01-16 | 2014-01-15 | Prolonged-release diphenidol composition |
| BR112015011351-6A BR112015011351B1 (pt) | 2013-01-16 | 2014-01-15 | Composição farmacêutica na forma de tablete em camada única de difenidol de liberação sustentada |
| PCT/IB2014/000044 WO2014111799A1 (es) | 2013-01-16 | 2014-01-15 | Composición de difenidol de liberación prolongada |
| CA2889283A CA2889283C (en) | 2013-01-16 | 2014-01-15 | Prolonged-release diphenidol composition |
| GT201500038A GT201500038A (es) | 2013-01-16 | 2015-02-19 | Composicion de difenidol de liberacion prolongada. |
| DO2015000089A DOP2015000089A (es) | 2013-01-16 | 2015-04-17 | Composición de difenidol de liberación prolongada |
| CL2015001128A CL2015001128A1 (es) | 2013-01-16 | 2015-04-29 | Composicion farmaceutica de difenidol de liberación prolongada; util como agente antiemetico y antivertigo. |
| CR20150275A CR20150275A (es) | 2013-01-16 | 2015-05-25 | Composición de difenidol de liberación prolongada |
| ECIEPI201530460A ECSP15030460A (es) | 2013-01-16 | 2015-07-15 | Composición de difenidol de liberación prolongada |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2013000662A MX356789B (es) | 2013-01-16 | 2013-01-16 | Composición de difenidol de liberación prolongada. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013000662A MX2013000662A (es) | 2014-07-16 |
| MX356789B true MX356789B (es) | 2018-06-12 |
Family
ID=51209070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013000662A MX356789B (es) | 2013-01-16 | 2013-01-16 | Composición de difenidol de liberación prolongada. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10188610B2 (es) |
| BR (1) | BR112015011351B1 (es) |
| CA (1) | CA2889283C (es) |
| CL (1) | CL2015001128A1 (es) |
| CR (1) | CR20150275A (es) |
| DO (1) | DOP2015000089A (es) |
| EC (1) | ECSP15030460A (es) |
| GT (1) | GT201500038A (es) |
| MX (1) | MX356789B (es) |
| PE (1) | PE20150888A1 (es) |
| WO (1) | WO2014111799A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108283625A (zh) * | 2018-04-26 | 2018-07-17 | 江苏四环生物制药有限公司 | 一种盐酸地芬尼多片的制备方法 |
| CN110638776A (zh) * | 2019-10-25 | 2020-01-03 | 仁和堂药业有限公司 | 盐酸地芬尼多片的制备工艺 |
| CN110638775A (zh) * | 2019-10-25 | 2020-01-03 | 仁和堂药业有限公司 | 一种盐酸地芬尼多片剂及其应用 |
| CN110934842A (zh) * | 2019-11-26 | 2020-03-31 | 卓和药业集团有限公司 | 盐酸地芬尼多片的制备方法 |
| CN112315925A (zh) * | 2020-11-16 | 2021-02-05 | 仁和堂药业有限公司 | 盐酸米安色林片及其制备工艺 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6143108A (ja) * | 1984-08-03 | 1986-03-01 | Nippon Shinyaku Co Ltd | 医薬品製剤及びその製造法 |
| WO1991006281A1 (fr) * | 1989-10-26 | 1991-05-16 | Nippon Shinyaku Co., Ltd. | Preparation gastrique |
| CN1935140A (zh) | 2005-09-19 | 2007-03-28 | 长沙佰川医药科技开发有限责任公司 | 复方盐酸地芬尼多分散片剂及其制备方法 |
| FR2891459B1 (fr) * | 2005-09-30 | 2007-12-28 | Flamel Technologies Sa | Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant |
| WO2008146178A2 (en) * | 2007-05-30 | 2008-12-04 | Wockhardt Research Centre | A novel tablet dosage form |
| KR101051630B1 (ko) * | 2008-10-02 | 2011-07-26 | 한국유나이티드제약 주식회사 | 용출률과 복용편의성이 향상된 트리메부틴 서방정 |
| CA2753057C (en) * | 2009-03-03 | 2018-09-11 | Xenoport, Inc. | Sustained release oral dosage forms of an r-baclofen prodrug |
-
2013
- 2013-01-16 MX MX2013000662A patent/MX356789B/es active IP Right Grant
-
2014
- 2014-01-15 WO PCT/IB2014/000044 patent/WO2014111799A1/es not_active Ceased
- 2014-01-15 PE PE2015000603A patent/PE20150888A1/es active IP Right Grant
- 2014-01-15 US US14/759,683 patent/US10188610B2/en active Active
- 2014-01-15 CA CA2889283A patent/CA2889283C/en active Active
- 2014-01-15 BR BR112015011351-6A patent/BR112015011351B1/pt active IP Right Grant
-
2015
- 2015-02-19 GT GT201500038A patent/GT201500038A/es unknown
- 2015-04-17 DO DO2015000089A patent/DOP2015000089A/es unknown
- 2015-04-29 CL CL2015001128A patent/CL2015001128A1/es unknown
- 2015-05-25 CR CR20150275A patent/CR20150275A/es unknown
- 2015-07-15 EC ECIEPI201530460A patent/ECSP15030460A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2013000662A (es) | 2014-07-16 |
| US10188610B2 (en) | 2019-01-29 |
| BR112015011351B1 (pt) | 2021-11-23 |
| CR20150275A (es) | 2015-07-08 |
| ECSP15030460A (es) | 2017-08-31 |
| BR112015011351A2 (pt) | 2017-07-11 |
| DOP2015000089A (es) | 2015-05-15 |
| WO2014111799A1 (es) | 2014-07-24 |
| US20150352051A1 (en) | 2015-12-10 |
| CA2889283C (en) | 2020-12-29 |
| GT201500038A (es) | 2019-08-02 |
| CL2015001128A1 (es) | 2015-10-09 |
| CA2889283A1 (en) | 2014-07-24 |
| PE20150888A1 (es) | 2015-06-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX387322B (es) | Formulaciones de inhibidor de demetilasa 1 especifica para lisina (lsd1). | |
| JOP20200122A1 (ar) | مركبات مفيدة لتثبيط cdk7 | |
| PH12019501970A1 (en) | Pharmaceutical compositions for combination therapy | |
| MY192084A (en) | Pyrazolo-heteroaryl derivative, preparation method and medical use thereof | |
| SG11201811697SA (en) | Glucagon derivative, conjugate thereof, composition comprising same and therapeutic use thereof | |
| HRP20250119T1 (hr) | Kdm1a inhibitor i njegova primjena u terapiji | |
| PH12017500281A1 (en) | Pyrrolopyrimidine compounds used as tlr7 agonist | |
| WO2016060996A3 (en) | Interleukin-15 compositions and uses thereof | |
| MX2016016666A (es) | Derivados de acido boronico y usos terapeuticos de los mismos. | |
| MX2016015093A (es) | Derivados de acido boronico y sus usos terapeuticos. | |
| MX363347B (es) | Sal de omecamtiv mecarbilo y proceso para preparar la sal. | |
| HRP20210529T1 (hr) | Inhibitori za mk2 i njihove uporabe | |
| CO2019008103A2 (es) | Composiciones farmacéuticas para terapia de combinación | |
| MY157673A (en) | Pharmaceutical compositions comprising hydromorphone and naloxone | |
| MX374944B (es) | Derivado de piranocromenil fenol, y composición farmacéutica para tratar un síndrome metabólico o enfermedad inflamatoria. | |
| EA201692043A1 (ru) | Лекарственная форма иммунодепрессанта | |
| MX392182B (es) | Combinaciones de dosis fija y formulaciones que comprenden ácido 8-hidroxi-2,2,14,14 tetrametilpentadecanodioico (etc1002) y ezetimiba y métodos para tratar o reducir el riesgo de enfermedad cardiovascular. | |
| MY191219A (en) | Therapeutic agent for fibrosis | |
| MX356789B (es) | Composición de difenidol de liberación prolongada. | |
| TN2019000032A1 (en) | Pharmaceutical compositions and uses directed to lysosomal storage disorders | |
| AR090073A1 (es) | N-etil-n-fenil-1,2-dihidro-4,5-di-hidroxi-1-metil-2-oxo-3-quinolinacarboxamida, su preparacion y usos | |
| AR090975A1 (es) | N-etil-4-hidroxil-1-metil-5-(metil(2,3,4,5,6-pentahidroxihexil)amino)-2-oxo-n-fenil-1,2-dihidroquinolina-3-carboxamida | |
| MX2018014129A (es) | Composiciones farmaceuticas de oligomero de morfolino fosforodiamidato. | |
| MX2017012022A (es) | Compuestos organicos. | |
| UA116499C2 (uk) | (r)-пірліндол та його фармацевтично прийнятні солі для застосування в медицині |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HC | Change of company name or juridical status |
Owner name: ICONKRETE 2012, S.L. |
|
| FG | Grant or registration |