MX349254B - Compuestos para el tratamiento del sindrome metabolico. - Google Patents
Compuestos para el tratamiento del sindrome metabolico.Info
- Publication number
- MX349254B MX349254B MX2013011124A MX2013011124A MX349254B MX 349254 B MX349254 B MX 349254B MX 2013011124 A MX2013011124 A MX 2013011124A MX 2013011124 A MX2013011124 A MX 2013011124A MX 349254 B MX349254 B MX 349254B
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- metabolic syndrome
- compounds
- metabolic
- type
- Prior art date
Links
- 208000001145 Metabolic Syndrome Diseases 0.000 title abstract 3
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 208000030159 metabolic disease Diseases 0.000 abstract 2
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 208000016097 disease of metabolism Diseases 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
- A23L33/165—Complexes or chelates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/326—Foods, ingredients or supplements having a functional effect on health having effect on cardiovascular health
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/3262—Foods, ingredients or supplements having a functional effect on health having an effect on blood cholesterol
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/328—Foods, ingredients or supplements having a functional effect on health having effect on glycaemic control and diabetes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/332—Promoters of weight control and weight loss
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/92—Oral administration
Abstract
La presente invención se refiere a nuevos compuestos de fórmula I o II, a su síntesis y a su uso en el tratamiento del síndrome metabólico, particularmente para el tratamiento de la diabetes de tipo I o de tipo II y/o el síndrome metabólico o enfermedades metabólicas o trastornos metabólicos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161468163P | 2011-03-28 | 2011-03-28 | |
PCT/EP2012/055570 WO2012130912A1 (en) | 2011-03-28 | 2012-03-28 | Compounds for treatment of metabolic syndrome |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013011124A MX2013011124A (es) | 2014-03-31 |
MX349254B true MX349254B (es) | 2017-07-19 |
Family
ID=45974264
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013011124A MX349254B (es) | 2011-03-28 | 2012-03-28 | Compuestos para el tratamiento del sindrome metabolico. |
Country Status (16)
Country | Link |
---|---|
US (2) | US9440966B2 (es) |
EP (1) | EP2691394B1 (es) |
JP (1) | JP6049216B2 (es) |
KR (1) | KR101784284B1 (es) |
CN (2) | CN103596949A (es) |
AU (1) | AU2012234230B2 (es) |
BR (1) | BR112013024602A2 (es) |
CA (1) | CA2831716C (es) |
DK (1) | DK2691394T3 (es) |
ES (1) | ES2635415T3 (es) |
IL (1) | IL228630A (es) |
MX (1) | MX349254B (es) |
PL (1) | PL2691394T3 (es) |
PT (1) | PT2691394T (es) |
RU (1) | RU2615136C2 (es) |
WO (1) | WO2012130912A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106317180B (zh) * | 2015-06-24 | 2019-09-13 | 首都医科大学 | β-咔啉-3-甲酰-Orn-AA-NHCH2C6H5其合成,活性和应用 |
WO2018142379A1 (en) * | 2017-02-06 | 2018-08-09 | Joslin Diabetes Center, Inc. | Methods and compositions for treating metabolic disorders |
CA3053059C (en) | 2017-03-14 | 2023-11-07 | Juan Carlos Agreda Navajas | Compounds for use in the prevention and/or treatment of non-alcoholic fat liver disease and non-alcoholic steatohepatitis |
CN109134460B (zh) * | 2018-08-02 | 2021-04-06 | 南开大学 | 一种β-咔啉类化合物的合成方法 |
CN109666615B (zh) | 2019-02-20 | 2021-03-19 | 无限极(中国)有限公司 | 一种益生菌组合物及其应用 |
CN109628358B (zh) | 2019-02-20 | 2021-03-19 | 无限极(中国)有限公司 | 一种复合益生菌及其应用 |
CN110585202A (zh) * | 2019-10-27 | 2019-12-20 | 淮安市厚沐医疗技术咨询中心 | 一种β-咔啉生物碱及其葡萄糖苷用于抑制肝脏糖异生的用途 |
WO2021195603A1 (en) * | 2020-03-27 | 2021-09-30 | Virginia Polytechnic Institute And State University | Anti-malarial compounds and uses thereof |
CN112047940B (zh) * | 2020-08-28 | 2021-06-29 | 南通大学 | 含1-(3,4-二甲氧基苯基)-β-咔啉单元的吡唑化合物的制备与用途 |
CN111892596B (zh) * | 2020-08-28 | 2022-07-15 | 南通大学 | 含多氟吡唑结构的β-咔啉类化合物的制备和应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES273769A1 (es) | 1961-01-18 | 1962-06-01 | Geigy Ag J R | Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico |
DE69904595T2 (de) * | 1998-06-12 | 2003-11-27 | Sod Conseils Rech Applic | Betacarbolinverbindungen |
RU2271350C2 (ru) * | 2000-06-09 | 2006-03-10 | Санофи-Авентис Дойчланд Гмбх | Производные ацилфенилмочевины, фармацевтическая композиция и способ ее получения |
BRPI0409263A (pt) * | 2003-04-09 | 2006-03-28 | Millennium Pharm Inc | composto; composição farmacêutica; método para tratar uma doença mediada por ikk e método para inibir ikk em um paciente que dele necessita |
WO2008103470A2 (en) * | 2007-02-21 | 2008-08-28 | Trustees Of Columbia University In The City Of New York | Oncogenic-ras-signal dependent lethal compounds |
EP2033962A1 (en) * | 2007-08-22 | 2009-03-11 | 4Sc Ag | Tetracyclic indolopyridines as EG5 inhibitors |
US8143269B2 (en) * | 2008-10-03 | 2012-03-27 | Calcimedica, Inc. | Inhibitors of store operated calcium release |
WO2010080756A2 (en) * | 2009-01-06 | 2010-07-15 | Osteogenex, Inc. | Harmine derivatives for reducing body weight |
-
2012
- 2012-03-28 AU AU2012234230A patent/AU2012234230B2/en active Active
- 2012-03-28 PT PT127146058T patent/PT2691394T/pt unknown
- 2012-03-28 RU RU2013147629A patent/RU2615136C2/ru active
- 2012-03-28 CA CA2831716A patent/CA2831716C/en active Active
- 2012-03-28 US US14/007,868 patent/US9440966B2/en active Active
- 2012-03-28 KR KR1020137027716A patent/KR101784284B1/ko active IP Right Grant
- 2012-03-28 MX MX2013011124A patent/MX349254B/es active IP Right Grant
- 2012-03-28 ES ES12714605.8T patent/ES2635415T3/es active Active
- 2012-03-28 PL PL12714605T patent/PL2691394T3/pl unknown
- 2012-03-28 EP EP12714605.8A patent/EP2691394B1/en active Active
- 2012-03-28 CN CN201280026176.3A patent/CN103596949A/zh active Pending
- 2012-03-28 CN CN201710886050.8A patent/CN107652283B/zh active Active
- 2012-03-28 DK DK12714605.8T patent/DK2691394T3/en active
- 2012-03-28 JP JP2014501607A patent/JP6049216B2/ja active Active
- 2012-03-28 BR BR112013024602-2A patent/BR112013024602A2/pt not_active Application Discontinuation
- 2012-03-28 WO PCT/EP2012/055570 patent/WO2012130912A1/en active Application Filing
-
2013
- 2013-09-29 IL IL228630A patent/IL228630A/en active IP Right Grant
-
2016
- 2016-04-22 US US15/136,277 patent/US20160340355A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2691394B1 (en) | 2017-05-10 |
AU2012234230A1 (en) | 2013-10-17 |
DK2691394T3 (en) | 2017-08-28 |
EP2691394A1 (en) | 2014-02-05 |
US20150051204A1 (en) | 2015-02-19 |
PT2691394T (pt) | 2017-08-14 |
RU2013147629A (ru) | 2015-05-10 |
CN103596949A (zh) | 2014-02-19 |
CA2831716A1 (en) | 2012-10-04 |
RU2615136C2 (ru) | 2017-04-04 |
BR112013024602A2 (pt) | 2020-10-13 |
IL228630A (en) | 2017-03-30 |
CA2831716C (en) | 2018-06-12 |
CN107652283B (zh) | 2021-07-06 |
MX2013011124A (es) | 2014-03-31 |
KR20140025401A (ko) | 2014-03-04 |
US9440966B2 (en) | 2016-09-13 |
JP6049216B2 (ja) | 2016-12-21 |
CN107652283A (zh) | 2018-02-02 |
JP2014510741A (ja) | 2014-05-01 |
ES2635415T3 (es) | 2017-10-03 |
WO2012130912A1 (en) | 2012-10-04 |
IL228630A0 (en) | 2013-12-31 |
AU2012234230B2 (en) | 2016-12-01 |
KR101784284B1 (ko) | 2017-10-11 |
PL2691394T3 (pl) | 2017-10-31 |
US20160340355A1 (en) | 2016-11-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2013011124A (es) | Compuestos para el tratamiento del sindrome metabolico. | |
TN2015000283A1 (fr) | Functionalized exendin-4 derivatives | |
MY170713A (en) | Treatment protocol of diabetes type 2 | |
EA201391033A1 (ru) | Ингибиторы bace-2 для лечения метаболических расстройств | |
NZ707139A (en) | Compositions, methods and uses for the treatment of diabetes and related conditions by controlling blood glucose level | |
MX356728B (es) | Combinación farmacéutica para usar en el tratamiento de pacientes que padecen diabetes de tipo 2. | |
MY165620A (en) | Cyclopropylamines as lsd1 inhibitors | |
BR112015000399A2 (pt) | derivados de pirazolil pirimidina | |
MA33939B1 (fr) | 5-alcynyl-pyrimidines | |
MX2014015423A (es) | Analogos de peptido de exedina-4. | |
ZA201402907B (en) | Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated pathologies | |
PL2771329T3 (pl) | Nowe związki di-podstawione 3,4-diamino-3-cyklobuteno- 1,2-dionu do zastosowania w leczeniu patologii, w których pośredniczą chemokiny | |
UA113849C2 (xx) | Застосування сигма-лігандів при болю, пов'язаному з діабетом 2 типу | |
PH12015500746A1 (en) | Benzamides | |
MX2011006006A (es) | Compuestos, composicion farmaceutica y metodos para utilizarse en el tratamiento de trastornos metabolicos. | |
EA201201623A1 (ru) | Лечение диабета 2 типа | |
WO2012104823A3 (en) | Pyridopyrimidinone compounds in the treatment of neurodegenerative diseases | |
NZ702239A (en) | Heteroaryl compounds and methods of use thereof | |
UA103197C2 (uk) | Застосування ніфуртимоксу для лікування хвороб, спричинених трихомонадами | |
MX348147B (es) | Biarilsulfonamidas utiles en el tratamiento de la inflamacion y cancer. | |
MX2014003455A (es) | Derivados de metanosulfonamida sustituidos con arilo o n-heteroarilo como ligandos de receptor vanilloide. | |
MY173722A (en) | Oligosaccharides composition for preventing or reducing the risk of metabolic syndrome | |
MX2014005538A (es) | 1-piridazinil-hidroxiimino-3-fenil-propanos como agonistas de proteina g-receptor acoplado a acido biliar 1 (gpbar1). | |
GB201114389D0 (en) | Novel compounds | |
MX2013006670A (es) | Derivado de 2-carboxamida-4-piperazinil-benzofurano. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |