MX347693B - 7-{(3s,4s)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidine-1-yl }-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinolin e-3-carboxylic acid crystal. - Google Patents
7-{(3s,4s)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidine-1-yl }-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinolin e-3-carboxylic acid crystal.Info
- Publication number
- MX347693B MX347693B MX2014005007A MX2014005007A MX347693B MX 347693 B MX347693 B MX 347693B MX 2014005007 A MX2014005007 A MX 2014005007A MX 2014005007 A MX2014005007 A MX 2014005007A MX 347693 B MX347693 B MX 347693B
- Authority
- MX
- Mexico
- Prior art keywords
- fluoropyrrolidine
- dihydroquinolin
- cyclopropylamino
- fluoroethyl
- oxo
- Prior art date
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The purpose of the present invention is to provide a hydrochloride crystal, a hydrochloride hydrate crystal, and a methanesulfonate crystal of the compound represented by formula (1).These crystals are less susceptible to decomposition caused by the effects of light, and also have high preservation stability and high water solubility compared to a free crystal of the compound (1).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20110246209 | 2011-11-10 | ||
JP2012071739 | 2012-03-27 | ||
PCT/JP2012/007195 WO2013069297A1 (en) | 2011-11-10 | 2012-11-09 | 7-{(3s,4s)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidine-1-yl}-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid crystal |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014005007A MX2014005007A (en) | 2014-07-09 |
MX347693B true MX347693B (en) | 2017-05-09 |
Family
ID=51830053
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014005007A MX347693B (en) | 2011-11-10 | 2012-11-09 | 7-{(3s,4s)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidine-1-yl }-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinolin e-3-carboxylic acid crystal. |
Country Status (1)
Country | Link |
---|---|
MX (1) | MX347693B (en) |
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2012
- 2012-11-09 MX MX2014005007A patent/MX347693B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
MX2014005007A (en) | 2014-07-09 |
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