MX347693B - 7-{(3s,4s)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidine-1-yl }-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinolin e-3-carboxylic acid crystal. - Google Patents

7-{(3s,4s)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidine-1-yl }-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinolin e-3-carboxylic acid crystal.

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Publication number
MX347693B
MX347693B MX2014005007A MX2014005007A MX347693B MX 347693 B MX347693 B MX 347693B MX 2014005007 A MX2014005007 A MX 2014005007A MX 2014005007 A MX2014005007 A MX 2014005007A MX 347693 B MX347693 B MX 347693B
Authority
MX
Mexico
Prior art keywords
fluoropyrrolidine
dihydroquinolin
cyclopropylamino
fluoroethyl
oxo
Prior art date
Application number
MX2014005007A
Other languages
Spanish (es)
Other versions
MX2014005007A (en
Inventor
Goto Akinori
Minagawa Wataru
Funada Keiko
Araya Ichiro
Nagao Muneki
Original Assignee
Kyorin Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk
Priority claimed from PCT/JP2012/007195 external-priority patent/WO2013069297A1/en
Publication of MX2014005007A publication Critical patent/MX2014005007A/en
Publication of MX347693B publication Critical patent/MX347693B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The purpose of the present invention is to provide a hydrochloride crystal, a hydrochloride hydrate crystal, and a methanesulfonate crystal of the compound represented by formula (1).These crystals are less susceptible to decomposition caused by the effects of light, and also have high preservation stability and high water solubility compared to a free crystal of the compound (1).
MX2014005007A 2011-11-10 2012-11-09 7-{(3s,4s)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidine-1-yl }-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinolin e-3-carboxylic acid crystal. MX347693B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20110246209 2011-11-10
JP2012071739 2012-03-27
PCT/JP2012/007195 WO2013069297A1 (en) 2011-11-10 2012-11-09 7-{(3s,4s)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidine-1-yl}-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid crystal

Publications (2)

Publication Number Publication Date
MX2014005007A MX2014005007A (en) 2014-07-09
MX347693B true MX347693B (en) 2017-05-09

Family

ID=51830053

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014005007A MX347693B (en) 2011-11-10 2012-11-09 7-{(3s,4s)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidine-1-yl }-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinolin e-3-carboxylic acid crystal.

Country Status (1)

Country Link
MX (1) MX347693B (en)

Also Published As

Publication number Publication date
MX2014005007A (en) 2014-07-09

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