IN2014DN03277A - - Google Patents
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- Publication number
- IN2014DN03277A IN2014DN03277A IN3277DEN2014A IN2014DN03277A IN 2014DN03277 A IN2014DN03277 A IN 2014DN03277A IN 3277DEN2014 A IN3277DEN2014 A IN 3277DEN2014A IN 2014DN03277 A IN2014DN03277 A IN 2014DN03277A
- Authority
- IN
- India
- Prior art keywords
- crystal
- hydrochloride
- compound
- crystals
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The purpose of the present invention is to provide a hydrochloride crystal a hydrochloride hydrate crystal and a methanesulfonate crystal of the compound represented by formula (1). These crystals are less susceptible to decomposition caused by the effects of light and also have high preservation stability and high water solubility compared to a free crystal of the compound (1).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011246209 | 2011-11-10 | ||
| JP2012071739 | 2012-03-27 | ||
| PCT/JP2012/007195 WO2013069297A1 (en) | 2011-11-10 | 2012-11-09 | 7-{(3s,4s)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidine-1-yl}-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid crystal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN03277A true IN2014DN03277A (en) | 2015-05-22 |
Family
ID=48289529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3277DEN2014 IN2014DN03277A (en) | 2011-11-10 | 2012-11-09 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US9090587B2 (en) |
| EP (2) | EP3112359B1 (en) |
| JP (4) | JP5871948B2 (en) |
| KR (2) | KR20140098074A (en) |
| CN (2) | CN103930414B (en) |
| AU (1) | AU2016273899B2 (en) |
| BR (1) | BR112014010765B1 (en) |
| CA (1) | CA2855022C (en) |
| ES (2) | ES2747303T3 (en) |
| IN (1) | IN2014DN03277A (en) |
| NZ (1) | NZ623808A (en) |
| RU (2) | RU2017109814A (en) |
| SA (1) | SA112330992B1 (en) |
| SG (2) | SG11201401817TA (en) |
| TW (1) | TWI547492B (en) |
| WO (1) | WO2013069297A1 (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SA112330992B1 (en) * | 2011-11-10 | 2015-09-13 | كيورين فارماسوتيكال كو.، ليمتد | Crystalline form of the 7-{(3S,4S)-3 [(cyclopropylamino)methyl]-4- fluoropyrrolidine-1-YL}-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-OXO- 1,4-dihydroquinoline-3-carboxylic acid |
| JP6349306B2 (en) * | 2013-04-25 | 2018-06-27 | 杏林製薬株式会社 | tablet |
| CN105338982B (en) | 2013-04-25 | 2017-10-10 | 杏林制药株式会社 | Solid pharmaceutical composition |
| JP5700740B1 (en) * | 2013-04-25 | 2015-04-15 | 杏林製薬株式会社 | Solid pharmaceutical composition |
| GB201402071D0 (en) | 2014-02-07 | 2014-03-26 | Galapagos Nv | Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders |
| WO2016063542A1 (en) * | 2014-10-23 | 2016-04-28 | 杏林製薬株式会社 | Solid pharmaceutical composition |
| US20170246160A1 (en) * | 2014-10-23 | 2017-08-31 | Kyorin Pharmaceutical Co., Ltd. | Solid pharmaceutical composition |
| EA201791995A1 (en) * | 2015-03-13 | 2017-12-29 | Керин Фармасьютикал Ко., Лтд. | MEANS FOR THE TREATMENT OF RESPIRATORY INFECTION |
| US10617684B2 (en) | 2015-06-02 | 2020-04-14 | Kyorin Pharmaceutical Co., Ltd. | Aqueous drug |
| WO2016195021A1 (en) | 2015-06-02 | 2016-12-08 | 杏林製薬株式会社 | Aqueous liquid formulation |
| EP3305295A4 (en) * | 2015-06-02 | 2019-02-20 | Kyorin Pharmaceutical Co., Ltd. | Aqueous drug |
| US20210137913A1 (en) | 2017-06-16 | 2021-05-13 | Kyorin Pharmaceutical Co., Ltd. | Therapeutic agent for aspiration pneumonia, lung suppuration, or lung abscess |
| TW202415375A (en) * | 2017-06-16 | 2024-04-16 | 日商杏林製藥股份有限公司 | Method of treating aspiration pneumonia, lung abscess or pulmonary abscess |
| WO2023032083A1 (en) | 2021-09-01 | 2023-03-09 | 株式会社日立ハイテクサイエンス | Charged particle beam device and method for adjusting charged particle beam device |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA944369B (en) * | 1993-08-27 | 1995-02-13 | Hokuriku Seuyaku Co Ltd | 5-amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative |
| CN1158846A (en) * | 1995-05-09 | 1997-09-10 | 昆山市康壮达兽药厂 | Synthesis technology of norfluxacini hydrochloride |
| US20030119060A1 (en) | 2001-08-10 | 2003-06-26 | Desrosiers Peter J. | Apparatuses and methods for creating and testing pre-formulations and systems for same |
| WO2003076428A1 (en) * | 2002-03-08 | 2003-09-18 | Daiichi Pharmaceutical Co., Ltd. | Quinolonecarboxylic acid derivative |
| WO2005026147A1 (en) | 2003-09-10 | 2005-03-24 | Kyorin Pharmaceutical Co., Ltd. | 7-(4-substituted 3- cyclopropylaminomethyl-1 pyrrolidinyl) quinolonecarboxylic acid derivative |
| CN101003540A (en) * | 2006-01-18 | 2007-07-25 | 广州白云山制药股份有限公司广州白云山制药总厂 | Anti infectious compound and usage |
| SA112330992B1 (en) * | 2011-11-10 | 2015-09-13 | كيورين فارماسوتيكال كو.، ليمتد | Crystalline form of the 7-{(3S,4S)-3 [(cyclopropylamino)methyl]-4- fluoropyrrolidine-1-YL}-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-OXO- 1,4-dihydroquinoline-3-carboxylic acid |
-
2012
- 2012-11-07 SA SA112330992A patent/SA112330992B1/en unknown
- 2012-11-09 US US14/352,141 patent/US9090587B2/en not_active Expired - Fee Related
- 2012-11-09 EP EP16177827.9A patent/EP3112359B1/en not_active Not-in-force
- 2012-11-09 CA CA2855022A patent/CA2855022C/en not_active Expired - Fee Related
- 2012-11-09 WO PCT/JP2012/007195 patent/WO2013069297A1/en active Application Filing
- 2012-11-09 JP JP2013542858A patent/JP5871948B2/en active Active
- 2012-11-09 SG SG11201401817TA patent/SG11201401817TA/en unknown
- 2012-11-09 TW TW101141841A patent/TWI547492B/en active
- 2012-11-09 RU RU2017109814A patent/RU2017109814A/en unknown
- 2012-11-09 SG SG10201608167UA patent/SG10201608167UA/en unknown
- 2012-11-09 KR KR1020147012681A patent/KR20140098074A/en active Search and Examination
- 2012-11-09 CN CN201280055120.0A patent/CN103930414B/en active Active
- 2012-11-09 NZ NZ623808A patent/NZ623808A/en not_active IP Right Cessation
- 2012-11-09 BR BR112014010765-3A patent/BR112014010765B1/en not_active IP Right Cessation
- 2012-11-09 CN CN201510329284.3A patent/CN104945375B/en active Active
- 2012-11-09 ES ES16177827T patent/ES2747303T3/en active Active
- 2012-11-09 ES ES12846895.6T patent/ES2621664T3/en active Active
- 2012-11-09 EP EP12846895.6A patent/EP2778159B1/en not_active Not-in-force
- 2012-11-09 RU RU2014123567A patent/RU2615509C2/en active
- 2012-11-09 IN IN3277DEN2014 patent/IN2014DN03277A/en unknown
- 2012-11-09 KR KR1020197015481A patent/KR102162208B1/en active IP Right Grant
-
2015
- 2015-06-17 US US14/741,713 patent/US9328089B2/en not_active Ceased
- 2015-08-25 JP JP2015165879A patent/JP6514069B2/en active Active
-
2016
- 2016-12-14 AU AU2016273899A patent/AU2016273899B2/en not_active Ceased
-
2017
- 2017-05-08 JP JP2017092125A patent/JP6349435B2/en active Active
-
2018
- 2018-05-02 US US15/969,342 patent/USRE47785E1/en not_active Expired - Fee Related
- 2018-07-13 JP JP2018132781A patent/JP6818719B2/en active Active
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