MX2025005020A - Inhibidores de cromanona alostericos de fosfoinositido 3-quinasa (pi3k) para el tratamiento de enfermedades - Google Patents
Inhibidores de cromanona alostericos de fosfoinositido 3-quinasa (pi3k) para el tratamiento de enfermedadesInfo
- Publication number
- MX2025005020A MX2025005020A MX2025005020A MX2025005020A MX2025005020A MX 2025005020 A MX2025005020 A MX 2025005020A MX 2025005020 A MX2025005020 A MX 2025005020A MX 2025005020 A MX2025005020 A MX 2025005020A MX 2025005020 A MX2025005020 A MX 2025005020A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- chromenone
- phosphoinositide
- allosteric
- pi3k
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/03—Monoamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263421636P | 2022-11-02 | 2022-11-02 | |
| US202263423879P | 2022-11-09 | 2022-11-09 | |
| PCT/US2023/036445 WO2024097205A1 (en) | 2022-11-02 | 2023-10-31 | Allosteric chromenone inhibitors of phosphoinositide 3-kinase (pi3k) for the treatment of disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2025005020A true MX2025005020A (es) | 2025-08-01 |
Family
ID=88978500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2025005020A MX2025005020A (es) | 2022-11-02 | 2025-04-30 | Inhibidores de cromanona alostericos de fosfoinositido 3-quinasa (pi3k) para el tratamiento de enfermedades |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4612136A1 (enExample) |
| JP (1) | JP7712994B2 (enExample) |
| KR (1) | KR20250097960A (enExample) |
| CN (1) | CN120476112A (enExample) |
| AU (1) | AU2023373670A1 (enExample) |
| MX (1) | MX2025005020A (enExample) |
| TW (1) | TWI887826B (enExample) |
| WO (1) | WO2024097205A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119874676A (zh) * | 2023-10-25 | 2025-04-25 | 海创药业股份有限公司 | 一种pi3k抑制剂及其制备方法和用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA21528A1 (fr) * | 1988-04-06 | 1989-12-31 | Lipha | Composants substituants du flavonoide, leurs sels, leurs manufactures et produits contenant ces matieres . |
| NZ538420A (en) * | 2002-08-16 | 2007-06-29 | Kinacia Pty Ltd | Inhibition of phosphoinositide 3-kinase beta |
| US8519155B2 (en) * | 2008-10-31 | 2013-08-27 | C-A-I-R Biosciences Gmbh | Choline and tromethamine salt of licofelone |
| EP3369730B1 (en) * | 2012-11-05 | 2020-08-05 | Emory University | 7,8-dihydoxyflavone and 7,8-substituted flavone derivatives, compositions, and methods related thereto |
| KR102485620B1 (ko) * | 2017-03-03 | 2023-01-09 | 길리애드 사이언시즈, 인코포레이티드 | Acc 억제제 및 그의 고체 형태를 제조하는 방법 |
| AR121719A1 (es) * | 2020-04-03 | 2022-06-29 | Petra Pharma Corp | Inhibidores alostéricos de cromenona del fosfoinosítido 3-quinasa (pi3k) para el tratamiento de enfermedades |
| AU2022268900B2 (en) * | 2021-05-03 | 2024-12-19 | Petra Pharma Corporation | Allosteric chromenone inhibitors of phosphoinositide 3-kinase (pi3k) for the treatment of disease |
-
2023
- 2023-10-31 WO PCT/US2023/036445 patent/WO2024097205A1/en not_active Ceased
- 2023-10-31 KR KR1020257018231A patent/KR20250097960A/ko active Pending
- 2023-10-31 TW TW112141733A patent/TWI887826B/zh active
- 2023-10-31 JP JP2023186694A patent/JP7712994B2/ja active Active
- 2023-10-31 CN CN202380089690.XA patent/CN120476112A/zh active Pending
- 2023-10-31 AU AU2023373670A patent/AU2023373670A1/en active Pending
- 2023-10-31 EP EP23814294.7A patent/EP4612136A1/en active Pending
-
2025
- 2025-04-30 MX MX2025005020A patent/MX2025005020A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TWI887826B (zh) | 2025-06-21 |
| KR20250097960A (ko) | 2025-06-30 |
| EP4612136A1 (en) | 2025-09-10 |
| AU2023373670A1 (en) | 2025-05-15 |
| TW202432100A (zh) | 2024-08-16 |
| JP7712994B2 (ja) | 2025-07-24 |
| JP2024067008A (ja) | 2024-05-16 |
| WO2024097205A1 (en) | 2024-05-10 |
| CN120476112A (zh) | 2025-08-12 |
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