MX2023012698A - Expansion de linfocitos en un solo recipiente. - Google Patents
Expansion de linfocitos en un solo recipiente.Info
- Publication number
- MX2023012698A MX2023012698A MX2023012698A MX2023012698A MX2023012698A MX 2023012698 A MX2023012698 A MX 2023012698A MX 2023012698 A MX2023012698 A MX 2023012698A MX 2023012698 A MX2023012698 A MX 2023012698A MX 2023012698 A MX2023012698 A MX 2023012698A
- Authority
- MX
- Mexico
- Prior art keywords
- lymphocytes
- single vessel
- vessel expansion
- population
- cells
- Prior art date
Links
- 210000004698 lymphocyte Anatomy 0.000 title abstract 3
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 2
- 102100027207 CD27 antigen Human genes 0.000 abstract 1
- 102100021260 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 Human genes 0.000 abstract 1
- 101000914511 Homo sapiens CD27 antigen Proteins 0.000 abstract 1
- 101000894906 Homo sapiens Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 Proteins 0.000 abstract 1
- 101000971533 Homo sapiens Killer cell lectin-like receptor subfamily G member 1 Proteins 0.000 abstract 1
- 101000914514 Homo sapiens T-cell-specific surface glycoprotein CD28 Proteins 0.000 abstract 1
- 102100021457 Killer cell lectin-like receptor subfamily G member 1 Human genes 0.000 abstract 1
- 102100027213 T-cell-specific surface glycoprotein CD28 Human genes 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/13—B-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4201—Neoantigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/98—Xeno-free medium and culture conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2302—Interleukin-2 (IL-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2312—Interleukin-12 (IL-12)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/1107—B cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2511/00—Cells for large scale production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21171565 | 2021-04-30 | ||
| PCT/EP2022/061639 WO2022229464A1 (en) | 2021-04-30 | 2022-04-29 | Single vessel expansion of lymphocytes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023012698A true MX2023012698A (es) | 2024-02-21 |
Family
ID=76034406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023012698A MX2023012698A (es) | 2021-04-30 | 2022-04-29 | Expansion de linfocitos en un solo recipiente. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240287454A1 (https=) |
| EP (1) | EP4330380A1 (https=) |
| JP (1) | JP2024517793A (https=) |
| KR (1) | KR20240026905A (https=) |
| CN (1) | CN117321189A (https=) |
| AU (1) | AU2022267777A1 (https=) |
| BR (1) | BR112023022485A2 (https=) |
| CA (1) | CA3214450A1 (https=) |
| MX (1) | MX2023012698A (https=) |
| WO (1) | WO2022229464A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115558641B (zh) * | 2022-11-14 | 2023-05-12 | 四川新生命干细胞科技股份有限公司 | 高纯度效应免疫细胞群及其培养方法、试剂组合物和应用 |
| WO2024261339A1 (en) | 2023-06-23 | 2024-12-26 | Tigen Pharma Sa | Lymphocyte-stimulatory matrix (lsm) and uses thereof for expansion of lymphocyte populations |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| US5350674A (en) | 1992-09-04 | 1994-09-27 | Becton, Dickinson And Company | Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof |
| CU23734A1 (es) | 2009-11-27 | 2011-11-15 | Centro Inmunologia Molecular | Polipéptidos inmunomoduladores derivados de la il-2 con actividad antagonista de esta citocina útiles en la terapia del cáncer y enfermedades infecciosas crónicas |
| EP2569633B1 (en) | 2010-05-14 | 2016-02-10 | The General Hospital Corporation | Compositions and methods of identifying tumor specific neoantigens |
| EP2983702A2 (en) | 2013-04-07 | 2016-02-17 | The Broad Institute, Inc. | Compositions and methods for personalized neoplasia vaccines |
| US20160310584A1 (en) | 2013-12-06 | 2016-10-27 | The Broad Institute Inc. | Formulations for neoplasia vaccines |
| KR20230076867A (ko) | 2013-12-20 | 2023-05-31 | 더 브로드 인스티튜트, 인코퍼레이티드 | 신생항원 백신과의 병용 요법 |
| EP3234130B1 (en) | 2014-12-19 | 2020-11-25 | The Broad Institute, Inc. | Methods for profiling the t-cell- receptor repertoire |
| IL294183B2 (en) | 2015-05-20 | 2023-10-01 | Dana Farber Cancer Inst Inc | shared neoantigens |
| EP3323070B1 (en) | 2015-07-14 | 2024-05-08 | Personal Genome Diagnostics Inc. | Neoantigen analysis |
| ES2970865T3 (es) | 2015-12-16 | 2024-05-31 | Gritstone Bio Inc | Identificación, fabricación y uso de neoantígenos |
| CA3034452A1 (en) | 2016-08-21 | 2018-03-01 | Adva Biotechnology Ltd. | Bioreactor and methods of use thereof |
| WO2018213803A1 (en) | 2017-05-19 | 2018-11-22 | Neon Therapeutics, Inc. | Immunogenic neoantigen identification |
| EP3707245A1 (en) * | 2017-11-06 | 2020-09-16 | Ludwig Institute for Cancer Research Ltd | Method for expansion of lymphocytes |
| US20230052157A1 (en) | 2019-12-12 | 2023-02-16 | Achilles Therapeutics Uk Limited | Method for obtaining nucleic acid for sequencing |
| JP2023510950A (ja) | 2020-01-20 | 2023-03-15 | アドヴァ バイオテクノロジー リミテッド | バイオリアクタを制御する装置及び方法 |
-
2022
- 2022-04-29 JP JP2023567114A patent/JP2024517793A/ja active Pending
- 2022-04-29 WO PCT/EP2022/061639 patent/WO2022229464A1/en not_active Ceased
- 2022-04-29 CA CA3214450A patent/CA3214450A1/en active Pending
- 2022-04-29 KR KR1020237041122A patent/KR20240026905A/ko active Pending
- 2022-04-29 EP EP22727052.7A patent/EP4330380A1/en active Pending
- 2022-04-29 AU AU2022267777A patent/AU2022267777A1/en not_active Abandoned
- 2022-04-29 MX MX2023012698A patent/MX2023012698A/es unknown
- 2022-04-29 US US18/288,893 patent/US20240287454A1/en active Pending
- 2022-04-29 CN CN202280031807.4A patent/CN117321189A/zh active Pending
- 2022-04-29 BR BR112023022485A patent/BR112023022485A2/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA3214450A1 (en) | 2022-11-03 |
| JP2024517793A (ja) | 2024-04-23 |
| WO2022229464A1 (en) | 2022-11-03 |
| BR112023022485A2 (pt) | 2024-01-09 |
| US20240287454A1 (en) | 2024-08-29 |
| EP4330380A1 (en) | 2024-03-06 |
| AU2022267777A1 (en) | 2023-10-05 |
| KR20240026905A (ko) | 2024-02-29 |
| CN117321189A (zh) | 2023-12-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2023012698A (es) | Expansion de linfocitos en un solo recipiente. | |
| MY199870A (en) | Microorganism comprising variant lyse and method of l-amino acid production using same | |
| MX2021005021A (es) | Proceso para producir celulas t geneticamente modificadas. | |
| Griffiths et al. | Unstable cytoplasms in Hawaiian strains of Neurospora intermedia | |
| EP0970701A3 (en) | Pellets derived from keratinocytes for use as wound healing substances | |
| NZ597742A (en) | Method of producing a polypeptide or virus of interest in a continuous cell culture | |
| DK0418354T3 (da) | Fremgangsmåde til in vitro reproduktion og vækst af celler i dyrkningsmedium | |
| WO2004090096A3 (en) | Methods for neural differentiation of embryonic stem cells using protease passaging techniques | |
| TW200741001A (en) | Method for production of t cell population | |
| WO2022047222A3 (en) | Crispr/cas9 multiplex knockout of host cell proteins | |
| WO2021250583A3 (en) | 3d culture of mesenchymal lineage precursor or stem cells | |
| IL161873A0 (en) | Production of cell suspensions | |
| MX2025000269A (es) | Sistema y metodo de cultivo celular multicamara | |
| MX2022010239A (es) | Poblaciones de linfocitos t gamma delta ex vivo. | |
| MX2022009958A (es) | Cepas de produccion adictas a cargas. | |
| WO2023158750A3 (en) | Systems for cell programming and methods thereof | |
| NO20021334D0 (no) | Fremgangsmåte for kultivering av celler, en membranmodul, anvendelse av en membranmodul og reaksjonssystem for kultiveringav celler | |
| EP4635527A3 (en) | Thymic constructs and uses thereof | |
| WO2024141710A3 (en) | An aquaculture system and methods for removing glycerol from the aquaculture system | |
| WO2024030965A3 (en) | Reinforced gas-permeable container | |
| DK1048725T3 (da) | Fremgangsmåde til fremstilling af pattedyrcellelinjer | |
| WO2024238712A3 (en) | Compositions and methods for multiplex engineering of immune cells | |
| WO2024236300A3 (en) | System for creating an oxygen gradient across a cell culture insert barrier | |
| HK30105656A2 (en) | Methods of preparing chimeric antigen receptor engineered cells | |
| MX2021011375A (es) | Cultivos de linfocitos t cd28, composiciones y métodos para su uso. |