MX2023012447A - Ergolinas novedosas y metodos para tratar los desordenes del humor. - Google Patents

Ergolinas novedosas y metodos para tratar los desordenes del humor.

Info

Publication number
MX2023012447A
MX2023012447A MX2023012447A MX2023012447A MX2023012447A MX 2023012447 A MX2023012447 A MX 2023012447A MX 2023012447 A MX2023012447 A MX 2023012447A MX 2023012447 A MX2023012447 A MX 2023012447A MX 2023012447 A MX2023012447 A MX 2023012447A
Authority
MX
Mexico
Prior art keywords
methods
mood disorders
ergolines
novel
treating mood
Prior art date
Application number
MX2023012447A
Other languages
English (en)
Spanish (es)
Inventor
Andrew Carry Kruegel
Original Assignee
Gilgamesh Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilgamesh Pharmaceuticals Inc filed Critical Gilgamesh Pharmaceuticals Inc
Publication of MX2023012447A publication Critical patent/MX2023012447A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C07D457/08—Lysergic acid amides in which the amide nitrogen is a member of a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX2023012447A 2021-04-23 2022-04-25 Ergolinas novedosas y metodos para tratar los desordenes del humor. MX2023012447A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163179053P 2021-04-23 2021-04-23
US202263308376P 2022-02-09 2022-02-09
PCT/US2022/026186 WO2022226408A1 (en) 2021-04-23 2022-04-25 Novel ergolines and methods of treating mood disorders

Publications (1)

Publication Number Publication Date
MX2023012447A true MX2023012447A (es) 2023-10-31

Family

ID=81648213

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023012447A MX2023012447A (es) 2021-04-23 2022-04-25 Ergolinas novedosas y metodos para tratar los desordenes del humor.

Country Status (10)

Country Link
US (1) US20240368151A1 (cg-RX-API-DMAC10.html)
EP (1) EP4326718A1 (cg-RX-API-DMAC10.html)
JP (1) JP2024516174A (cg-RX-API-DMAC10.html)
KR (1) KR20240019091A (cg-RX-API-DMAC10.html)
AU (1) AU2022262659A1 (cg-RX-API-DMAC10.html)
BR (1) BR112023021970A2 (cg-RX-API-DMAC10.html)
CA (1) CA3223210A1 (cg-RX-API-DMAC10.html)
IL (1) IL307880A (cg-RX-API-DMAC10.html)
MX (1) MX2023012447A (cg-RX-API-DMAC10.html)
WO (1) WO2022226408A1 (cg-RX-API-DMAC10.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230116703A1 (en) * 2021-04-23 2023-04-13 Gilgamesh Pharmaceuticals, Inc. Novel ergolines and methods of treating mood disorders
EP4329759A4 (en) 2021-04-30 2025-07-16 Mind Medicine Inc CRYSTALLINE FORMS OF LSD SALTS
US12611399B2 (en) 2021-05-04 2026-04-28 Definium Therapeutics US, Inc. Movement disorders
US20230064429A1 (en) 2021-08-19 2023-03-02 Mind Medicine, Inc. IMMEDIATE RELEASE FORMULATIONS OF d-LYSERGIC ACID DIETHYLAMIDE FOR THERAPEUTIC APPLICATIONS
CN119923261A (zh) * 2022-06-20 2025-05-02 思维医学股份有限公司 具有改良的lsd样作用的麦角酸衍生物
ES3066618T3 (en) * 2022-12-31 2026-05-13 Ceruvia Lifesciences Llc Salts of 2-bromolysergic acid diethylamide
JP2026515993A (ja) * 2023-05-04 2026-05-19 ギルガメッシュ・ファーマシューティカルズ・インコーポレイテッド 新規エルゴリン及び気分障害を処置する方法
WO2025194238A1 (en) * 2024-03-22 2025-09-25 Blife Therapeutics Inc. 2-bromo-lsd salts and polymorphs
WO2025235784A2 (en) * 2024-05-08 2025-11-13 Cy Biopharma Ag Ergoline derivatives and uses thereof
WO2025235800A1 (en) 2024-05-08 2025-11-13 Cy Biopharma Ag Ergoline derivatives and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2438259A (en) * 1948-03-23 D-lysergic acid diethyl amide
KR100477070B1 (ko) * 1994-03-25 2006-04-21 이소테크니카 인코포레이티드 중수소화작용에의한의약품의효능강화법
US12616706B2 (en) * 2019-03-07 2026-05-05 Arbormentis LLC Compositions and methods of use comprising substances with neural plasticity actions administered at non-psychedelic/psychotomimetic dosages and formulations
US20230295106A1 (en) * 2019-10-14 2023-09-21 The Regents Of The University Of California Ergoline-like compounds for promoting neural plasticity
WO2022008627A2 (en) * 2020-07-07 2022-01-13 Compass Pathfinder Limited Improved method for the production of lysergic acid diethylamide (lsd) and novel derivatives thereof

Also Published As

Publication number Publication date
JP2024516174A (ja) 2024-04-12
KR20240019091A (ko) 2024-02-14
BR112023021970A2 (pt) 2023-12-26
EP4326718A1 (en) 2024-02-28
AU2022262659A1 (en) 2023-10-19
IL307880A (en) 2023-12-01
CA3223210A1 (en) 2022-12-27
WO2022226408A1 (en) 2022-10-27
US20240368151A1 (en) 2024-11-07

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