MX2023009392A - Anticuerpo anti-vegf y uso del mismo. - Google Patents

Anticuerpo anti-vegf y uso del mismo.

Info

Publication number
MX2023009392A
MX2023009392A MX2023009392A MX2023009392A MX2023009392A MX 2023009392 A MX2023009392 A MX 2023009392A MX 2023009392 A MX2023009392 A MX 2023009392A MX 2023009392 A MX2023009392 A MX 2023009392A MX 2023009392 A MX2023009392 A MX 2023009392A
Authority
MX
Mexico
Prior art keywords
protein
vegf antibody
binding
vegf
isolated antigen
Prior art date
Application number
MX2023009392A
Other languages
English (en)
Inventor
Sujun Deng
Xiaowu Liu
Zhongzong Pan
Zongda Wang
Xiaodan Cao
Xueping Wang
Chunyin Gu
Original Assignee
Shanghai Jemincare Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Jemincare Pharmaceutical Co Ltd filed Critical Shanghai Jemincare Pharmaceutical Co Ltd
Publication of MX2023009392A publication Critical patent/MX2023009392A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Se proporciona una proteína de unión a antígeno aislada capaz de unirse a la proteína VEGF y/o capaz de bloquear la unión de la proteína VEGF a la proteína VEGFR. Además se proporciona el uso de la proteína de unión a antígeno aislada en la preparación de un fármaco.
MX2023009392A 2021-02-10 2022-02-09 Anticuerpo anti-vegf y uso del mismo. MX2023009392A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202110183560 2021-02-10
PCT/CN2022/075600 WO2022171109A1 (zh) 2021-02-10 2022-02-09 抗vegf抗体及其用途

Publications (1)

Publication Number Publication Date
MX2023009392A true MX2023009392A (es) 2023-11-09

Family

ID=82838272

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023009392A MX2023009392A (es) 2021-02-10 2022-02-09 Anticuerpo anti-vegf y uso del mismo.

Country Status (11)

Country Link
EP (1) EP4292661A1 (es)
JP (1) JP2024506664A (es)
KR (1) KR20230142838A (es)
CN (1) CN116897164A (es)
AU (1) AU2022220965A1 (es)
BR (1) BR112023016095A2 (es)
CA (1) CA3207763A1 (es)
IL (1) IL305092A (es)
MX (1) MX2023009392A (es)
TW (1) TW202246328A (es)
WO (1) WO2022171109A1 (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101148474B (zh) * 2006-09-21 2014-06-11 上海杰隆生物工程股份有限公司 人源人血管内皮生长因子单克隆抗体及其制备方法
CN102002104A (zh) * 2009-08-28 2011-04-06 江苏先声药物研究有限公司 一种抗vegf的单克隆抗体及含有该抗体的药物组合物
AU2017273169B2 (en) * 2016-06-03 2020-07-30 Aimed Bio Inc. Method for screening antibody using patient-derived tumor spheroids
CN114008075A (zh) * 2019-07-19 2022-02-01 神州细胞工程有限公司 人源化抗vegf单克隆抗体

Also Published As

Publication number Publication date
TW202246328A (zh) 2022-12-01
CN116897164A (zh) 2023-10-17
IL305092A (en) 2023-10-01
BR112023016095A2 (pt) 2023-11-14
AU2022220965A1 (en) 2023-08-31
CA3207763A1 (en) 2022-08-18
WO2022171109A1 (zh) 2022-08-18
KR20230142838A (ko) 2023-10-11
EP4292661A1 (en) 2023-12-20
JP2024506664A (ja) 2024-02-14

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