MX2023008729A - Tratamiento de colangiopatías con seladelpar. - Google Patents
Tratamiento de colangiopatías con seladelpar.Info
- Publication number
- MX2023008729A MX2023008729A MX2023008729A MX2023008729A MX2023008729A MX 2023008729 A MX2023008729 A MX 2023008729A MX 2023008729 A MX2023008729 A MX 2023008729A MX 2023008729 A MX2023008729 A MX 2023008729A MX 2023008729 A MX2023008729 A MX 2023008729A
- Authority
- MX
- Mexico
- Prior art keywords
- seladelpar
- cholangiopathies
- treatment
- fibrates
- intolerant
- Prior art date
Links
- JWHYSEDOYMYMNM-QGZVFWFLSA-N 2-[4-[(2r)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]sulfanyl-2-methylphenoxy]acetic acid Chemical compound C([C@@H](OCC)CSC=1C=C(C)C(OCC(O)=O)=CC=1)OC1=CC=C(C(F)(F)F)C=C1 JWHYSEDOYMYMNM-QGZVFWFLSA-N 0.000 title abstract 2
- 208000015163 Biliary Tract disease Diseases 0.000 title abstract 2
- 229950009639 seladelpar Drugs 0.000 title abstract 2
- 229940125753 fibrate Drugs 0.000 abstract 1
- ZXERDUOLZKYMJM-ZWECCWDJSA-N obeticholic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)CCC(O)=O)CC[C@H]21 ZXERDUOLZKYMJM-ZWECCWDJSA-N 0.000 abstract 1
- 229960001601 obeticholic acid Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Farming Of Fish And Shellfish (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- Ladders (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
El seladelpar y sus sales son útiles en el tratamiento de colangiopatías en sujetos quienes son intolerantes a, o tienen una respuesta inadecuada a, ácido obeticólico y/o fibratos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163144355P | 2021-02-01 | 2021-02-01 | |
| PCT/US2022/014464 WO2022165288A1 (en) | 2021-02-01 | 2022-01-29 | Treatment of cholangiopathies with seladelpar |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023008729A true MX2023008729A (es) | 2024-01-30 |
Family
ID=80787371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023008729A MX2023008729A (es) | 2021-02-01 | 2022-01-29 | Tratamiento de colangiopatías con seladelpar. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220241228A1 (es) |
| EP (1) | EP4225291B1 (es) |
| JP (1) | JP2024501358A (es) |
| KR (1) | KR20230107700A (es) |
| CN (1) | CN116761597A (es) |
| AU (1) | AU2022214948B2 (es) |
| CA (1) | CA3203235C (es) |
| DK (1) | DK4225291T3 (es) |
| IL (1) | IL304873A (es) |
| MX (1) | MX2023008729A (es) |
| WO (1) | WO2022165288A1 (es) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2378435T3 (es) | 2003-09-19 | 2012-04-12 | Janssen Pharmaceutica N.V. | �?cidos 4-((fenoxialquil)tio)-fenoxiacéticos y análogos |
| JO3006B1 (ar) | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
| US10272058B2 (en) | 2014-03-20 | 2019-04-30 | Cymabay Therapeutics, Inc. | Treatment of intrahepatic cholestatic diseases |
| CN106102734B (zh) | 2014-03-20 | 2019-05-14 | 西玛贝医药公司 | 肝内胆汁淤积性疾病的治疗 |
| CN107292528A (zh) | 2017-06-30 | 2017-10-24 | 阿里巴巴集团控股有限公司 | 车险风险预测方法、装置及服务器 |
| US10512622B2 (en) * | 2017-07-14 | 2019-12-24 | Cymabay Therapeutics, Inc. | Treatment of intrahepatic cholestatic diseases |
| PL3687523T3 (pl) | 2017-09-26 | 2022-02-21 | Cymabay Therapeutics, Inc. | Leczenie świądu cholestatycznego za pomocą seladelparu |
-
2022
- 2022-01-29 US US17/588,273 patent/US20220241228A1/en active Pending
- 2022-01-29 CA CA3203235A patent/CA3203235C/en active Active
- 2022-01-29 JP JP2023546245A patent/JP2024501358A/ja active Pending
- 2022-01-29 MX MX2023008729A patent/MX2023008729A/es unknown
- 2022-01-29 KR KR1020237022371A patent/KR20230107700A/ko not_active Application Discontinuation
- 2022-01-29 IL IL304873A patent/IL304873A/en unknown
- 2022-01-29 AU AU2022214948A patent/AU2022214948B2/en active Active
- 2022-01-29 DK DK22704693.5T patent/DK4225291T3/da active
- 2022-01-29 EP EP22704693.5A patent/EP4225291B1/en active Active
- 2022-01-29 CN CN202280012684.XA patent/CN116761597A/zh active Pending
- 2022-01-29 WO PCT/US2022/014464 patent/WO2022165288A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| KR20230107700A (ko) | 2023-07-17 |
| CA3203235A1 (en) | 2022-08-04 |
| DK4225291T3 (da) | 2024-05-27 |
| JP2024501358A (ja) | 2024-01-11 |
| NZ800627A (en) | 2023-08-25 |
| EP4225291B1 (en) | 2024-03-13 |
| US20220241228A1 (en) | 2022-08-04 |
| AU2022214948A1 (en) | 2023-06-29 |
| AU2022214948B2 (en) | 2023-07-13 |
| CA3203235C (en) | 2024-04-09 |
| EP4225291A1 (en) | 2023-08-16 |
| CN116761597A (zh) | 2023-09-15 |
| WO2022165288A1 (en) | 2022-08-04 |
| IL304873A (en) | 2023-10-01 |
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