MX2023004673A - Sensibilidad al daño del adn como un nuevo biomarcador para detección de cáncer y susceptibilidad al cáncer. - Google Patents

Sensibilidad al daño del adn como un nuevo biomarcador para detección de cáncer y susceptibilidad al cáncer.

Info

Publication number
MX2023004673A
MX2023004673A MX2023004673A MX2023004673A MX2023004673A MX 2023004673 A MX2023004673 A MX 2023004673A MX 2023004673 A MX2023004673 A MX 2023004673A MX 2023004673 A MX2023004673 A MX 2023004673A MX 2023004673 A MX2023004673 A MX 2023004673A
Authority
MX
Mexico
Prior art keywords
cancer
dna damage
detection
susceptibility
biomarker
Prior art date
Application number
MX2023004673A
Other languages
English (en)
Inventor
Arne Faisst
Julia Godau
Oliver Schicht
Original Assignee
4D Lifetec Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 4D Lifetec Ag filed Critical 4D Lifetec Ag
Publication of MX2023004673A publication Critical patent/MX2023004673A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/10—Detection mode being characterised by the assay principle
    • C12Q2565/125—Electrophoretic separation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La invención se refiere a un marcador que puede usarse como biomarcador para la detección de cáncer. Más específicamente, la presente invención se refiere al análisis de la sensibilidad al daño del ADN genómico (DDS) como un biomarcador para el cáncer o la susceptibilidad al cáncer u otros estados de enfermedad caracterizados por alteraciones de la respuesta al daño del ADN (DDR). El biomarcador de la invención también se puede usar para estudiar el efecto de la medicación, los factores de riesgo y/o los impactos ambientales sobre la susceptibilidad al cáncer o, más generalmente, que alteran la sensibilidad al ADN genómico (DDS).
MX2023004673A 2020-10-22 2021-10-19 Sensibilidad al daño del adn como un nuevo biomarcador para detección de cáncer y susceptibilidad al cáncer. MX2023004673A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH13632020 2020-10-22
PCT/EP2021/078953 WO2022084318A1 (en) 2020-10-22 2021-10-19 Dna damage sensitivity as a new biomarker for detection of cancer and cancer susceptibility

Publications (1)

Publication Number Publication Date
MX2023004673A true MX2023004673A (es) 2023-08-10

Family

ID=81290114

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023004673A MX2023004673A (es) 2020-10-22 2021-10-19 Sensibilidad al daño del adn como un nuevo biomarcador para detección de cáncer y susceptibilidad al cáncer.

Country Status (8)

Country Link
US (1) US20230383362A1 (es)
EP (1) EP4232821A1 (es)
JP (1) JP2023546212A (es)
KR (1) KR20230120122A (es)
CN (1) CN116648620A (es)
AU (1) AU2021363573A1 (es)
MX (1) MX2023004673A (es)
WO (1) WO2022084318A1 (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201216174D0 (en) 2012-09-11 2012-10-24 Univ Bradford Method of determining a predisposition to disease states characterised by free redical induced dna damage
JP6875052B2 (ja) 2015-03-06 2021-05-19 フォーディー ライフテック アーゲー４Ｄ Ｌｉｆｅｔｅｃ Ａｇ 単細胞電気泳動のためのゲル電気泳動装置、ゲル電気泳動システム、支持板、同システムを使用してコメットアッセイを実施するための方法、および同方法を実施するソフトウェア
EP3508841A1 (en) * 2018-01-08 2019-07-10 4D Lifetec AG Single cell gel electrophoresis

Also Published As

Publication number Publication date
EP4232821A1 (en) 2023-08-30
JP2023546212A (ja) 2023-11-01
CN116648620A (zh) 2023-08-25
WO2022084318A1 (en) 2022-04-28
KR20230120122A (ko) 2023-08-16
US20230383362A1 (en) 2023-11-30
AU2021363573A1 (en) 2023-06-22
AU2021363573A9 (en) 2024-05-02

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