MX2023002331A - Anticuerpo biespecifico anti factor de crecimiento endoteliar vascular (vegf) y anti ligando 1 de la muerte programada 1 (pd-l1), composicion farmaceutica y usos del mismo. - Google Patents

Anticuerpo biespecifico anti factor de crecimiento endoteliar vascular (vegf) y anti ligando 1 de la muerte programada 1 (pd-l1), composicion farmaceutica y usos del mismo.

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Publication number
MX2023002331A
MX2023002331A MX2023002331A MX2023002331A MX2023002331A MX 2023002331 A MX2023002331 A MX 2023002331A MX 2023002331 A MX2023002331 A MX 2023002331A MX 2023002331 A MX2023002331 A MX 2023002331A MX 2023002331 A MX2023002331 A MX 2023002331A
Authority
MX
Mexico
Prior art keywords
vegf
bispecific antibody
functional area
protein functional
same
Prior art date
Application number
MX2023002331A
Other languages
English (en)
Spanish (es)
Inventor
Cheng Chen
Andy Tsun
Xiaoniu Miao
Zhijun Yuan
Weifeng Huang
Joanne Tsoyue
Original Assignee
Biotheus Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotheus Inc filed Critical Biotheus Inc
Publication of MX2023002331A publication Critical patent/MX2023002331A/es

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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
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    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
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MX2023002331A 2020-08-31 2021-08-30 Anticuerpo biespecifico anti factor de crecimiento endoteliar vascular (vegf) y anti ligando 1 de la muerte programada 1 (pd-l1), composicion farmaceutica y usos del mismo. MX2023002331A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202010897917.1A CN114106190B (zh) 2020-08-31 2020-08-31 一种抗vegf/pd-l1双特异性抗体及其用途
PCT/CN2021/115308 WO2022042719A1 (zh) 2020-08-31 2021-08-30 抗vegf-抗pd-l1双特异性抗体、其药物组合物及用途

Publications (1)

Publication Number Publication Date
MX2023002331A true MX2023002331A (es) 2023-04-20

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MX2023002331A MX2023002331A (es) 2020-08-31 2021-08-30 Anticuerpo biespecifico anti factor de crecimiento endoteliar vascular (vegf) y anti ligando 1 de la muerte programada 1 (pd-l1), composicion farmaceutica y usos del mismo.

Country Status (9)

Country Link
US (2) US12325759B2 (enExample)
EP (2) EP4729545A1 (enExample)
JP (1) JP7885203B2 (enExample)
KR (1) KR20230061433A (enExample)
CN (2) CN114106190B (enExample)
AU (1) AU2021334042A1 (enExample)
CA (1) CA3192812A1 (enExample)
MX (1) MX2023002331A (enExample)
WO (1) WO2022042719A1 (enExample)

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CN116731188B (zh) * 2022-03-02 2025-02-14 三优生物医药(上海)有限公司 抗pd-l1和vegf双特异性抗体及其应用
CN114736303A (zh) * 2022-03-17 2022-07-12 英诺湖医药(杭州)有限公司 抗pd-l1和4-1bb的双功能抗体及其医药用途
CN117186238A (zh) * 2022-05-31 2023-12-08 宜明昂科生物医药技术（上海）股份有限公司 靶向pd-l1和vegf的重组融合蛋白及其制备和用途
WO2024032664A1 (zh) * 2022-08-09 2024-02-15 上海济煜医药科技有限公司 一种靶向pd-l1和vegf的抗体及其应用
JP2026500781A (ja) * 2022-12-29 2026-01-08 シャンハイ・ヘンリウス・バイオテック・インコーポレイテッド 抗ｐｄｌ１／ｖｅｇｆ抗体及び使用方法
CN120361206A (zh) * 2024-01-25 2025-07-25 中山康方生物医药有限公司 抗pd-1-抗vegfa的双特异性抗体的医药用途
WO2025184858A1 (en) 2024-03-07 2025-09-12 Biotheus Inc. Combination therapy comprising a bispecific anti-vegf-a and anti-pd-l1 antibody and a chemotherapy for cancer treatment
WO2025185161A1 (en) 2024-03-07 2025-09-12 Biotheus Inc. Combination therapy comprising a bispecific anti-vegf-a and anti-pd-l1 antibody and a chemotherapy for cancer treatment
WO2025185733A1 (en) 2024-03-07 2025-09-12 Biotheus Inc. Combination therapy comprising a pd-1/pd-l1 and vegf/vegfr binding agent and a chemotherapy for cancer treatment
CN120025456B (zh) * 2024-03-13 2025-11-07 寻济生物科技（北京）有限公司 一种抗vegfa融合构建体及其制备方法和应用
WO2026067774A1 (en) * 2024-09-30 2026-04-02 Hanx Biopharmaceuticals (Wuhan) Co., Ltd. Antibodies targeting vegf and pd-1/pd-l1 and uses thereof
CN121324641B (zh) * 2025-12-15 2026-04-21 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 一种检测内罗毕羊病病毒的试剂盒

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