MX2023002161A - Composiciones y metodos para enfermedades neurologicas. - Google Patents

Composiciones y metodos para enfermedades neurologicas.

Info

Publication number
MX2023002161A
MX2023002161A MX2023002161A MX2023002161A MX2023002161A MX 2023002161 A MX2023002161 A MX 2023002161A MX 2023002161 A MX2023002161 A MX 2023002161A MX 2023002161 A MX2023002161 A MX 2023002161A MX 2023002161 A MX2023002161 A MX 2023002161A
Authority
MX
Mexico
Prior art keywords
compositions
methods
neurological diseases
engineered receptors
modulating
Prior art date
Application number
MX2023002161A
Other languages
English (en)
Spanish (es)
Inventor
Stefanie Makinson
Jr Anthony Lau
Jr Orion P Keifer
Alexander Naka
Original Assignee
Trames Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trames Bio Inc filed Critical Trames Bio Inc
Publication of MX2023002161A publication Critical patent/MX2023002161A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0085Brain, e.g. brain implants; Spinal cord
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0619Neurons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MX2023002161A 2020-08-21 2021-08-20 Composiciones y metodos para enfermedades neurologicas. MX2023002161A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063068890P 2020-08-21 2020-08-21
PCT/US2021/046915 WO2022040535A2 (en) 2020-08-21 2021-08-20 Compositions and methods for neurological diseases

Publications (1)

Publication Number Publication Date
MX2023002161A true MX2023002161A (es) 2023-05-18

Family

ID=80350587

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023002161A MX2023002161A (es) 2020-08-21 2021-08-20 Composiciones y metodos para enfermedades neurologicas.

Country Status (11)

Country Link
US (1) US20240317834A1 (https=)
EP (1) EP4200020A4 (https=)
JP (1) JP2023538130A (https=)
KR (1) KR20230061409A (https=)
CN (1) CN116802201A (https=)
AU (1) AU2021329529A1 (https=)
BR (1) BR112023003167A2 (https=)
CA (1) CA3192604A1 (https=)
IL (1) IL300816A (https=)
MX (1) MX2023002161A (https=)
WO (1) WO2022040535A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117487904B (zh) * 2023-12-28 2024-05-31 湖南家辉生物技术有限公司 Gabrb3基因突变体、突变体蛋白、试剂、试剂盒及应用
CN119331917B (zh) * 2024-10-28 2025-10-17 北京爱思益普生物科技股份有限公司 能够表达GlyR α1/β型GlyR的细胞株及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL304040B2 (en) * 2016-07-07 2024-09-01 Hughes Howard Med Inst Modified ligand-gated ion channels and methods of use
US10538571B2 (en) * 2017-11-27 2020-01-21 Coda Biotherapeutics, Inc. Compositions and methods for neurological diseases
AU2020334147A1 (en) * 2019-08-21 2022-03-31 Trames Bio, Inc. Compositions and methods for neurological diseases

Also Published As

Publication number Publication date
WO2022040535A3 (en) 2022-03-31
EP4200020A2 (en) 2023-06-28
BR112023003167A2 (pt) 2023-05-02
US20240317834A1 (en) 2024-09-26
AU2021329529A9 (en) 2025-03-13
EP4200020A4 (en) 2024-11-20
CN116802201A (zh) 2023-09-22
JP2023538130A (ja) 2023-09-06
KR20230061409A (ko) 2023-05-08
IL300816A (en) 2023-04-01
WO2022040535A2 (en) 2022-02-24
AU2021329529A1 (en) 2023-04-27
CA3192604A1 (en) 2022-02-24

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