IL300816A - Preparations and methods for neurological diseases - Google Patents
Preparations and methods for neurological diseasesInfo
- Publication number
- IL300816A IL300816A IL300816A IL30081623A IL300816A IL 300816 A IL300816 A IL 300816A IL 300816 A IL300816 A IL 300816A IL 30081623 A IL30081623 A IL 30081623A IL 300816 A IL300816 A IL 300816A
- Authority
- IL
- Israel
- Prior art keywords
- receptor
- engineered
- neuron
- ligand
- engineered receptor
- Prior art date
Links
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Classifications
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Virology (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063068890P | 2020-08-21 | 2020-08-21 | |
| PCT/US2021/046915 WO2022040535A2 (en) | 2020-08-21 | 2021-08-20 | Compositions and methods for neurological diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL300816A true IL300816A (en) | 2023-04-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| IL300816A IL300816A (en) | 2020-08-21 | 2021-08-20 | Preparations and methods for neurological diseases |
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|---|---|
| US (1) | US20240317834A1 (https=) |
| EP (1) | EP4200020A4 (https=) |
| JP (1) | JP2023538130A (https=) |
| KR (1) | KR20230061409A (https=) |
| CN (1) | CN116802201A (https=) |
| AU (1) | AU2021329529A1 (https=) |
| BR (1) | BR112023003167A2 (https=) |
| CA (1) | CA3192604A1 (https=) |
| IL (1) | IL300816A (https=) |
| MX (1) | MX2023002161A (https=) |
| WO (1) | WO2022040535A2 (https=) |
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| CN117487904B (zh) * | 2023-12-28 | 2024-05-31 | 湖南家辉生物技术有限公司 | Gabrb3基因突变体、突变体蛋白、试剂、试剂盒及应用 |
| CN119331917B (zh) * | 2024-10-28 | 2025-10-17 | 北京爱思益普生物科技股份有限公司 | 能够表达GlyR α1/β型GlyR的细胞株及其制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| IL304040B2 (en) * | 2016-07-07 | 2024-09-01 | Hughes Howard Med Inst | Modified ligand-gated ion channels and methods of use |
| US10538571B2 (en) * | 2017-11-27 | 2020-01-21 | Coda Biotherapeutics, Inc. | Compositions and methods for neurological diseases |
| AU2020334147A1 (en) * | 2019-08-21 | 2022-03-31 | Trames Bio, Inc. | Compositions and methods for neurological diseases |
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2021
- 2021-08-20 IL IL300816A patent/IL300816A/en unknown
- 2021-08-20 WO PCT/US2021/046915 patent/WO2022040535A2/en not_active Ceased
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- 2021-08-20 BR BR112023003167A patent/BR112023003167A2/pt unknown
Also Published As
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|---|---|
| WO2022040535A3 (en) | 2022-03-31 |
| EP4200020A2 (en) | 2023-06-28 |
| BR112023003167A2 (pt) | 2023-05-02 |
| US20240317834A1 (en) | 2024-09-26 |
| AU2021329529A9 (en) | 2025-03-13 |
| EP4200020A4 (en) | 2024-11-20 |
| MX2023002161A (es) | 2023-05-18 |
| CN116802201A (zh) | 2023-09-22 |
| JP2023538130A (ja) | 2023-09-06 |
| KR20230061409A (ko) | 2023-05-08 |
| WO2022040535A2 (en) | 2022-02-24 |
| AU2021329529A1 (en) | 2023-04-27 |
| CA3192604A1 (en) | 2022-02-24 |
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