MX2022014896A - Anticuerpos anti-cldn18.2 y usos para diagnostico de los mismos. - Google Patents
Anticuerpos anti-cldn18.2 y usos para diagnostico de los mismos.Info
- Publication number
- MX2022014896A MX2022014896A MX2022014896A MX2022014896A MX2022014896A MX 2022014896 A MX2022014896 A MX 2022014896A MX 2022014896 A MX2022014896 A MX 2022014896A MX 2022014896 A MX2022014896 A MX 2022014896A MX 2022014896 A MX2022014896 A MX 2022014896A
- Authority
- MX
- Mexico
- Prior art keywords
- antibodies
- diagnosis
- antigen
- present disclosure
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5753—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the stomach or small intestine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57557—Immunoassay; Biospecific binding assay; Materials therefor for cancer of other specific parts of the body, e.g. brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2020092092 | 2020-05-25 | ||
| PCT/CN2021/095411 WO2021238831A1 (en) | 2020-05-25 | 2021-05-24 | Anti-cldn18.2 antibodies and diagnostic uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022014896A true MX2022014896A (es) | 2023-01-04 |
Family
ID=78745623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022014896A MX2022014896A (es) | 2020-05-25 | 2021-05-24 | Anticuerpos anti-cldn18.2 y usos para diagnostico de los mismos. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230331836A1 (https=) |
| EP (1) | EP4157885A4 (https=) |
| JP (1) | JP2023527937A (https=) |
| KR (1) | KR20230016212A (https=) |
| CN (1) | CN115836090A (https=) |
| AU (1) | AU2021279777A1 (https=) |
| CA (1) | CA3184008A1 (https=) |
| MX (1) | MX2022014896A (https=) |
| TW (1) | TWI878541B (https=) |
| WO (1) | WO2021238831A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117295524A (zh) | 2021-06-02 | 2023-12-26 | 百奥泰生物制药股份有限公司 | 药物偶联物及其用途 |
| CN114539410B (zh) * | 2022-03-15 | 2023-09-05 | 苏州量化细胞生物科技有限公司 | Cldn18.2结合抗体、探针及在cldn18.2表达细胞的单细胞测序中的应用 |
| WO2023196882A1 (en) * | 2022-04-06 | 2023-10-12 | Zai Lab (Us) Llc | Claudin 18.2 immunohistochemistry assay and use thereof |
| CN114428174B (zh) * | 2022-04-07 | 2022-07-08 | 北京肿瘤医院(北京大学肿瘤医院) | 一种胃癌预后生物标志物及其应用 |
| WO2024199673A1 (en) * | 2023-03-31 | 2024-10-03 | Università Degli Studi Di Verona | Methods for predicting and improving therapeutic efficacy of cancer treatments and methods for cancer prognosis |
| WO2024211459A1 (en) * | 2023-04-04 | 2024-10-10 | Zai Lab (Shanghai) Co., Ltd | Use of anti-claudin antibody for cancer treatment based on certain biomarkers |
| CN121399468A (zh) * | 2023-05-08 | 2026-01-23 | 安捷伦科技有限公司 | 诊断和治疗癌症的免疫组织化学(ihc)方案和方法 - 密封蛋白18.2 |
| EP4720132A1 (en) * | 2023-06-03 | 2026-04-08 | Suzhou Transcenta Therapeutics Co., Ltd. | Combination therapies involving claudin 18.2 antagonists for treatment of cancer |
| KR20260028757A (ko) * | 2023-06-08 | 2026-03-04 | 안텐진 바이올로직스 리미티드 | 항-cldn18.2 항체 및 이의 진단적 용도 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10254601A1 (de) * | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| EP1790664A1 (en) * | 2005-11-24 | 2007-05-30 | Ganymed Pharmaceuticals AG | Monoclonal antibodies against claudin-18 for treatment of cancer |
| WO2013167153A1 (en) * | 2012-05-09 | 2013-11-14 | Ganymed Pharmaceuticals Ag | Antibodies useful in cancer diagnosis |
| WO2014146672A1 (en) * | 2013-03-18 | 2014-09-25 | Ganymed Pharmaceuticals Ag | Therapy involving antibodies against claudin 18.2 for treatment of cancer |
| US10858415B2 (en) * | 2014-01-29 | 2020-12-08 | Tron—Translationale Onkologie An Der Universitatsmedizin Der Johannes Guttenberg-Universitat Mainz Gemeinnuizige Gmbh | Peptide mimotopes of claudin 18.2 and uses thereof |
| WO2016165762A1 (en) * | 2015-04-15 | 2016-10-20 | Ganymed Pharmaceuticals Ag | Drug conjugates comprising antibodies against claudin 18.2 |
| WO2016180468A1 (en) * | 2015-05-11 | 2016-11-17 | Biontech Cell & Gene Therapies Gmbh | Claudin-18.2-specific immunoreceptors and t cell epitopes |
| SG11202007055QA (en) * | 2018-03-08 | 2020-09-29 | Phanes Therapeutics Inc | Anti-claudin 18.2 antibodies and uses thereof |
| EP3765522A4 (en) * | 2018-03-14 | 2022-05-18 | Beijing Xuanyi Pharmasciences Co., Ltd. | ANTI-CLAUDIN 18.2 ANTIBODIES |
| US11059887B2 (en) * | 2018-05-18 | 2021-07-13 | Lanova Medicines Limited Company | Anti-claudin 18.2 antibodies and uses thereof |
| CN110606891B (zh) * | 2018-06-17 | 2022-12-06 | 上海健信生物医药科技有限公司 | 一种针对人cldn18.2的抗体分子,抗原结合片段及其医药用途 |
| KR20210050547A (ko) * | 2018-08-27 | 2021-05-07 | 난징 산홈 팔마세우티칼 컴퍼니 리미티드 | 항-클라우딘18.2 항체 및 이의 용도 |
| EP3872093A4 (en) * | 2018-10-22 | 2022-10-19 | Shanghai Genbase Biotechnology Co., Ltd. | ANTI-CLDN18.2 ANTIBODIES AND USES THEREOF |
| CN109762067B (zh) * | 2019-01-17 | 2020-02-28 | 北京天广实生物技术股份有限公司 | 结合人Claudin 18.2的抗体及其用途 |
-
2021
- 2021-05-24 WO PCT/CN2021/095411 patent/WO2021238831A1/en not_active Ceased
- 2021-05-24 MX MX2022014896A patent/MX2022014896A/es unknown
- 2021-05-24 JP JP2023515227A patent/JP2023527937A/ja active Pending
- 2021-05-24 US US17/927,740 patent/US20230331836A1/en active Pending
- 2021-05-24 AU AU2021279777A patent/AU2021279777A1/en active Pending
- 2021-05-24 TW TW110118625A patent/TWI878541B/zh active
- 2021-05-24 EP EP21812540.9A patent/EP4157885A4/en active Pending
- 2021-05-24 CA CA3184008A patent/CA3184008A1/en active Pending
- 2021-05-24 KR KR1020227045389A patent/KR20230016212A/ko active Pending
- 2021-05-24 CN CN202180041601.5A patent/CN115836090A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4157885A1 (en) | 2023-04-05 |
| US20230331836A1 (en) | 2023-10-19 |
| CN115836090A (zh) | 2023-03-21 |
| TW202212360A (zh) | 2022-04-01 |
| CA3184008A1 (en) | 2021-12-02 |
| AU2021279777A1 (en) | 2022-12-08 |
| KR20230016212A (ko) | 2023-02-01 |
| WO2021238831A1 (en) | 2021-12-02 |
| EP4157885A4 (en) | 2024-07-10 |
| JP2023527937A (ja) | 2023-06-30 |
| TWI878541B (zh) | 2025-04-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2022014896A (es) | Anticuerpos anti-cldn18.2 y usos para diagnostico de los mismos. | |
| AR120883A1 (es) | Anticuerpos anti-fgfr2b | |
| AR120886A1 (es) | Anticuerpos anti-fgfr2b | |
| BR112022003147A2 (pt) | Novos anticorpos anti-cldn18.2 | |
| MX2025000370A (es) | Anticuerpos anti-ctla4 y metodos para elaborarlos y usarlos | |
| MX2021012769A (es) | Anticuerpos bloqueadores cd73. | |
| BR112018014615A2 (pt) | composições de anticorpo para ror1 e métodos relacionados | |
| BR112021023024A2 (pt) | Anticorpo contra claudina 18a2 e uso do mesmo | |
| CO2024013551A2 (es) | Nuevos anticuerpos anti-cd3 y usos de los mismos | |
| CO2023018064A2 (es) | Anticuerpos anti-ccr8 y usos de los mismos | |
| CO2022001194A2 (es) | Moléculas de unión a claudina-6 y usos de las mismas | |
| MX2019011117A (es) | Anticuerpo b7-h3, fragmento de union a antigeno de los mismos y uso medico de los mismos. | |
| AR110114A1 (es) | ANTICUERPOS CONTRA b-AMILOIDE PIROGLUTAMATO Y SUS USOS | |
| AR120884A1 (es) | Anticuerpos anti-fgfr2b | |
| CO2022002573A2 (es) | Anticuerpos contra ilt2 y uso de los mismos | |
| CL2025002941A1 (es) | Anticuerpos anti-sirp-alfa. | |
| CR20170600A (es) | Anticuerpos del factor x1 y métodos de uso | |
| CO2023000557A2 (es) | Anticuerpos y métodos para tratar enfermedades asociadas a claudina | |
| CL2021000163A1 (es) | Anticuerpos anti-htra1 y metodos de usos de los mismos. (divisional de solicitud 201801139) | |
| MX2020003093A (es) | Anticuerpos anti-cd19 novedosos. | |
| CO2023011463A2 (es) | Nuevos anticuerpos anti-cd24 | |
| UY38520A (es) | Anticuerpos anti-pmel17, sus conjugados, composiciones que los comprenden, polinucleótidos, métodos y usos relacionados a los mismos | |
| MX2021004925A (es) | Variantes de adn-polimerasa modificadas. | |
| BR112021025720A2 (pt) | Conjugados anticorpo-fármaco de fator antitecido e métodos relacionados | |
| CO2023002375A2 (es) | Anticuerpos contra ilt2 y uso de los mismos |