MX2022013817A - Comparacion de copias de polinucleotidos con diferentes caracteristicas. - Google Patents
Comparacion de copias de polinucleotidos con diferentes caracteristicas.Info
- Publication number
- MX2022013817A MX2022013817A MX2022013817A MX2022013817A MX2022013817A MX 2022013817 A MX2022013817 A MX 2022013817A MX 2022013817 A MX2022013817 A MX 2022013817A MX 2022013817 A MX2022013817 A MX 2022013817A MX 2022013817 A MX2022013817 A MX 2022013817A
- Authority
- MX
- Mexico
- Prior art keywords
- polynucleotides
- copies
- populations
- different features
- comparing
- Prior art date
Links
- 108091033319 polynucleotide Proteins 0.000 title abstract 5
- 102000040430 polynucleotide Human genes 0.000 title abstract 5
- 239000002157 polynucleotide Substances 0.000 title abstract 5
- 108091034117 Oligonucleotide Proteins 0.000 abstract 2
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/16—Assays for determining copy number or wherein the copy number is of special importance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2545/00—Reactions characterised by their quantitative nature
- C12Q2545/10—Reactions characterised by their quantitative nature the purpose being quantitative analysis
- C12Q2545/113—Reactions characterised by their quantitative nature the purpose being quantitative analysis with an external standard/control, i.e. control reaction is separated from the test/target reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/50—Detection characterised by immobilisation to a surface
- C12Q2565/514—Detection characterised by immobilisation to a surface characterised by the use of the arrayed oligonucleotides as identifier tags, e.g. universal addressable array, anti-tag or tag complement array
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Abstract
Se proporciona un método que incluye hacer copias de dos o más poblaciones de polinucleótidos que incluyen secuencias identificadores, en donde las copias se unen a un sustrato, hibridar oligonucleótidos a las secuencias identificadores, y comparar una cantidad de oligonucleótidos hibridados a las copias de las dos o más poblaciones de polinucleótidos, en donde al menos una característica difiere entre las dos o más poblaciones de polinucleótidos o entre la elaboración de las copias de las dos o más poblaciones de polinucleótidos unidas al sustrato.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063031230P | 2020-05-28 | 2020-05-28 | |
| PCT/US2021/033834 WO2021242668A1 (en) | 2020-05-28 | 2021-05-24 | Comparing copies of polynucleotides with different features |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022013817A true MX2022013817A (es) | 2023-03-03 |
Family
ID=76502835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022013817A MX2022013817A (es) | 2020-05-28 | 2021-05-24 | Comparacion de copias de polinucleotidos con diferentes caracteristicas. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20210371908A1 (es) |
| EP (1) | EP4158059A1 (es) |
| JP (1) | JP2023528003A (es) |
| KR (1) | KR20230034941A (es) |
| CN (1) | CN115867672A (es) |
| AU (1) | AU2021280233A1 (es) |
| BR (1) | BR112022024008A2 (es) |
| CA (1) | CA3177270A1 (es) |
| IL (1) | IL297944A (es) |
| MX (1) | MX2022013817A (es) |
| TW (1) | TW202146659A (es) |
| WO (1) | WO2021242668A1 (es) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060172314A1 (en) * | 2005-01-31 | 2006-08-03 | Song Min-Sun | Quantification of amplified nucleic acids |
| US8182994B2 (en) * | 2009-09-15 | 2012-05-22 | Illumina Cambridge Limited | Centroid markers for image analysis of high denisty clusters in complex polynucleotide sequencing |
| EP2820174B1 (en) * | 2012-02-27 | 2019-12-25 | The University of North Carolina at Chapel Hill | Methods and uses for molecular tags |
| WO2014142921A1 (en) | 2013-03-14 | 2014-09-18 | Illumina, Inc. | Modified polymerases for improved incorporation of nucleotide analogues |
| US10465232B1 (en) * | 2015-10-08 | 2019-11-05 | Trace Genomics, Inc. | Methods for quantifying efficiency of nucleic acid extraction and detection |
| EP3452618A4 (en) * | 2016-05-06 | 2019-12-11 | Regents of the University of Minnesota | ANALYTICAL STANDARDS AND METHOD FOR USE THEREOF |
| CA3044057A1 (en) * | 2016-11-18 | 2018-05-24 | Twist Bioscience Corporation | Polynucleotide libraries having controlled stoichiometry and synthesis thereof |
| WO2018170660A1 (en) * | 2017-03-20 | 2018-09-27 | Celula China Med-Technology Co., Ltd. | Method of correcting amplification bias in amplicon sequencing |
-
2021
- 2021-05-24 CA CA3177270A patent/CA3177270A1/en active Pending
- 2021-05-24 TW TW110118675A patent/TW202146659A/zh unknown
- 2021-05-24 BR BR112022024008A patent/BR112022024008A2/pt not_active Application Discontinuation
- 2021-05-24 IL IL297944A patent/IL297944A/en unknown
- 2021-05-24 AU AU2021280233A patent/AU2021280233A1/en active Pending
- 2021-05-24 EP EP21733288.1A patent/EP4158059A1/en active Pending
- 2021-05-24 US US17/328,151 patent/US20210371908A1/en active Pending
- 2021-05-24 CN CN202180038450.8A patent/CN115867672A/zh active Pending
- 2021-05-24 WO PCT/US2021/033834 patent/WO2021242668A1/en unknown
- 2021-05-24 JP JP2022572710A patent/JP2023528003A/ja active Pending
- 2021-05-24 MX MX2022013817A patent/MX2022013817A/es unknown
- 2021-05-24 KR KR1020227041061A patent/KR20230034941A/ko active Search and Examination
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021242668A1 (en) | 2021-12-02 |
| CA3177270A1 (en) | 2021-12-02 |
| US20210371908A1 (en) | 2021-12-02 |
| AU2021280233A1 (en) | 2022-12-08 |
| TW202146659A (zh) | 2021-12-16 |
| EP4158059A1 (en) | 2023-04-05 |
| BR112022024008A2 (pt) | 2022-12-27 |
| KR20230034941A (ko) | 2023-03-10 |
| JP2023528003A (ja) | 2023-07-03 |
| CN115867672A (zh) | 2023-03-28 |
| IL297944A (en) | 2023-01-01 |
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