MX2022012062A - Receptores de linfocitos t. - Google Patents

Receptores de linfocitos t.

Info

Publication number
MX2022012062A
MX2022012062A MX2022012062A MX2022012062A MX2022012062A MX 2022012062 A MX2022012062 A MX 2022012062A MX 2022012062 A MX2022012062 A MX 2022012062A MX 2022012062 A MX2022012062 A MX 2022012062A MX 2022012062 A MX2022012062 A MX 2022012062A
Authority
MX
Mexico
Prior art keywords
cell receptors
polynucleotides
polypeptides
vectors
cells
Prior art date
Application number
MX2022012062A
Other languages
English (en)
Inventor
Jasdeep Mann
Original Assignee
2Seventy Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 2Seventy Bio Inc filed Critical 2Seventy Bio Inc
Publication of MX2022012062A publication Critical patent/MX2022012062A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Rheumatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

Abstract

La presente descripción proporciona receptores de linfocitos T, polinucleótidos, polipéptidos, vectores, células, y métodos de uso mejorados.
MX2022012062A 2020-03-27 2021-03-26 Receptores de linfocitos t. MX2022012062A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063000800P 2020-03-27 2020-03-27
PCT/US2021/024370 WO2021195503A1 (en) 2020-03-27 2021-03-26 T cell receptors

Publications (1)

Publication Number Publication Date
MX2022012062A true MX2022012062A (es) 2023-01-11

Family

ID=77890524

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022012062A MX2022012062A (es) 2020-03-27 2021-03-26 Receptores de linfocitos t.

Country Status (11)

Country Link
US (1) US20230124640A1 (es)
EP (1) EP4126924A4 (es)
JP (1) JP2023519868A (es)
KR (1) KR20220160040A (es)
CN (1) CN115485294A (es)
AU (1) AU2021244594A1 (es)
BR (1) BR112022019380A2 (es)
CA (1) CA3177181A1 (es)
IL (1) IL296827A (es)
MX (1) MX2022012062A (es)
WO (1) WO2021195503A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117980326A (zh) 2021-07-14 2024-05-03 2赛文缇生物公司 与来自抗体的结合结构域融合的经工程化的t细胞受体
WO2023196997A2 (en) 2022-04-08 2023-10-12 2Seventy Bio, Inc. Multipartite receptor and signaling complexes
CN117003855B (zh) * 2023-09-20 2024-02-23 广州市老人院 一种t细胞受体及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1791865T3 (da) * 2004-06-29 2010-11-01 Immunocore Ltd Celler der udtrykker en modificeret T-cellerecptor
IL305550A (en) * 2011-10-28 2023-10-01 Regeneron Pharma Mice with a genetic change in the T cell receptor
KR20190101979A (ko) * 2016-12-02 2019-09-02 유니버시티 오브 써던 캘리포니아 합성 면역 수용체 및 이의 사용 방법
WO2019070541A1 (en) * 2017-10-03 2019-04-11 Juno Therapeutics, Inc. HPV-SPECIFIC BINDING MOLECULES
EP3714941A1 (en) * 2019-03-27 2020-09-30 Medigene Immunotherapies GmbH Mage-a4 tcrs
US20230044580A1 (en) * 2019-05-08 2023-02-09 2Seventy Bio, Inc. Engineered t cells

Also Published As

Publication number Publication date
WO2021195503A1 (en) 2021-09-30
AU2021244594A1 (en) 2022-12-01
JP2023519868A (ja) 2023-05-15
EP4126924A1 (en) 2023-02-08
IL296827A (en) 2022-11-01
CA3177181A1 (en) 2021-09-30
KR20220160040A (ko) 2022-12-05
BR112022019380A2 (pt) 2022-11-29
US20230124640A1 (en) 2023-04-20
CN115485294A (zh) 2022-12-16
EP4126924A4 (en) 2024-04-24

Similar Documents

Publication Publication Date Title
MX2022012062A (es) Receptores de linfocitos t.
CR20210687A (es) PROTEÍNAS DE FUSIÓN FLT3L-Fc Y MÉTODOS DE USO
WO2020092854A3 (en) Chimeric antigen receptors specific for g protein-coupled receptor class c group 5 member d (gprc5d)
MX2022001018A (es) Electrodos metalicos de bajo costo.
PH12019502897A1 (en) Flow cells
MX2020010235A (es) Vectores de expresion para receptores de engullimiento quimerico, celulas hospederas geneticamente modificadas y usos de los mismos.
MX2020009774A (es) Anticuerpos contra proteína alfa reguladora de señal y métodos de uso.
PH12020500677A1 (en) Neoantigens and uses thereof
EA201992001A1 (ru) Композиции и способы повышения экспрессии генов
EA201790554A1 (ru) Электрохимическая ячейка на основе галогенида цинка
MX2021014712A (es) Polipeptidos de transposasa y sus usos.
MX2019000643A (es) Receptores de antigenos quimericos y metodos de uso.
MX2020013977A (es) Proteínas quiméricas transmembrana y usos de las mismas.
MX2020008180A (es) Anticuerpos activables y métodos para elaborarlos y usarlos.
EA201892137A1 (ru) Композиции и способы получения антител, основанные на применении локусов, обеспечивающих повышенную экспрессию
MX2022005597A (es) Método y aparato de procesamiento de señalización, terminal y medio de almacenamiento.
MY191776A (en) Method for preparing electrocompetent yeast cells, and method for using said cells
MX2021010443A (es) Receptores de citocinas quimericos constitutivamente activos.
BR112022000876A2 (pt) Anticorpos imunomoduladores e métodos de uso destes
MX2018014523A (es) Baterias de flujo que tienen un electrodo con un gradiente de densidad y metodos para la produccion y uso de las mismas.
WO2016044586A3 (en) Copper based flow batteries
WO2018120843A9 (zh) 一种三功能分子及其应用
EP3627609A4 (en) ELECTROLYTIC SOLUTION, ELECTROCHEMICAL DEVICE, SECONDARY BATTERY, AND MODULE
MX2021002702A (es) Metodos para expandir celulas t del receptor de antigeno quimerico especificas de antigenos, composiciones y usos relacionados con las mismas.
EP3761423A4 (en) ELECTRODE FOR REDOX FLOW BATTERIES, REDOX FLOW BATTERY CELL AND REDOX FLOW BATTERY