MX2022011062A - Tratamientos para mejorar o disminuir el deterioro de la funcion mitocondrial. - Google Patents

Tratamientos para mejorar o disminuir el deterioro de la funcion mitocondrial.

Info

Publication number
MX2022011062A
MX2022011062A MX2022011062A MX2022011062A MX2022011062A MX 2022011062 A MX2022011062 A MX 2022011062A MX 2022011062 A MX2022011062 A MX 2022011062A MX 2022011062 A MX2022011062 A MX 2022011062A MX 2022011062 A MX2022011062 A MX 2022011062A
Authority
MX
Mexico
Prior art keywords
heart failure
impairment
mitochondrial
ejection fraction
therapies
Prior art date
Application number
MX2022011062A
Other languages
English (en)
Inventor
Hampar L Karageozian
John Y Park
Vicken H Karageozian
Original Assignee
Allegro Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allegro Pharmaceuticals Llc filed Critical Allegro Pharmaceuticals Llc
Publication of MX2022011062A publication Critical patent/MX2022011062A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)

Abstract

Tratamientos con péptidos para mejorar o disminuir el deterioro de la función mitocondrial. Estos tratamientos se pueden utilizar para trastornos que producen, son producidos, contribuyen o están relacionados con la disfunción mitocondrial, tales como neurodegeneración, enfermedad metabólica, insuficiencia cardíaca congestiva, insuficiencia cardíaca crónica con fracción de eyección reducida, insuficiencia cardíaca crónica con fracción de eyección conservada, síndrome de Barth, enfermedad renal y insuficiencia renal debido a angiografía renal percutánea para estenosis de la arteria renal, función del músculo esquelético alterada en ancianos, miopatía mitocondrial muscular primaria y neuropatía, lesión por isquemia-reperfusión e infecciones por protozoos, neuropatía periférica, trastornos dermatológicos y hemorroides inflamadas.
MX2022011062A 2020-03-06 2021-03-05 Tratamientos para mejorar o disminuir el deterioro de la funcion mitocondrial. MX2022011062A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062986361P 2020-03-06 2020-03-06
PCT/US2021/021171 WO2021178864A2 (en) 2020-03-06 2021-03-05 Treatments for improving or lessening impairment of mitochondrial function

Publications (1)

Publication Number Publication Date
MX2022011062A true MX2022011062A (es) 2022-09-21

Family

ID=77555308

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022011062A MX2022011062A (es) 2020-03-06 2021-03-05 Tratamientos para mejorar o disminuir el deterioro de la funcion mitocondrial.

Country Status (9)

Country Link
US (1) US20210275624A1 (es)
EP (1) EP4114429A2 (es)
JP (1) JP2023516431A (es)
KR (1) KR20220151628A (es)
CN (1) CN115605215A (es)
CA (1) CA3170752A1 (es)
IL (1) IL296239A (es)
MX (1) MX2022011062A (es)
WO (1) WO2021178864A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2504035B8 (en) * 2009-11-10 2019-06-05 Allegro Pharmaceuticals, LLC Compositions and methods for inhibiting cellular adhesion or directing diagnostic or therapeutic agents to rgd binding sites
EP4003392A4 (en) * 2019-07-26 2023-08-09 Allegro Pharmaceuticals, LLC PEPTIDES FOR THE TREATMENT OF NON-EXCESSIVE MACULAR DEGENERATION AND OTHER EYE DISEASES
KR20240060525A (ko) 2024-04-03 2024-05-08 한국세라믹기술원 산화갈륨 박막 구조물, 이의 제조방법 및 이를 포함하는 포토다이오드

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994015953A1 (en) * 1993-01-04 1994-07-21 The Regents Of The University Of California Platelet-specific therapeutic compound and method of treating platelet-mobilizing diseases
US9345739B2 (en) * 2007-11-08 2016-05-24 The General Hospital Corporation Methods and compositions for the treatment of proteinuric diseases
WO2011022056A2 (en) * 2009-08-18 2011-02-24 Medical College Of Georgia Research Institute, Inc. PEPTIDE MODULATORS OF THE δPKC INTERACTION WITH THE D SUBUNIT OF F1FO ATP SYNTHASE/ATPASE AND USES THEREOF
EP2504035B8 (en) * 2009-11-10 2019-06-05 Allegro Pharmaceuticals, LLC Compositions and methods for inhibiting cellular adhesion or directing diagnostic or therapeutic agents to rgd binding sites
AU2012253511A1 (en) * 2011-05-09 2014-01-09 Allegro Pharmaceuticals, Inc. Integrin receptor antagonists and their methods of use
WO2014059034A2 (en) * 2012-10-09 2014-04-17 President And Fellows Of Harvard College Nad biosynthesis and precursors for the treatment and prevention of cancer and proliferation
CA3020393A1 (en) * 2016-04-11 2017-10-19 Carnot, Llc Chiral peptides
US20180207227A1 (en) * 2017-01-19 2018-07-26 Allegro Pharmaceuticals, Inc. Therapeutic and Neuroprotective Peptides
CN110945010A (zh) * 2017-06-19 2020-03-31 急速制药有限责任公司 肽组合物和相关方法
EP3642214A2 (en) * 2017-06-19 2020-04-29 Gangadhara Ganapati Nicotinamide riboside derivatives and their uses
WO2019221959A1 (en) * 2018-05-16 2019-11-21 Peyman Gholam A Method of treating, reducing, or alleviating a medical condition in a patient
WO2020074937A1 (en) * 2018-10-09 2020-04-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of alpha-v-integrin (cd51) inhibitors for the treatment of cardiac fibrosis

Also Published As

Publication number Publication date
KR20220151628A (ko) 2022-11-15
JP2023516431A (ja) 2023-04-19
CN115605215A (zh) 2023-01-13
WO2021178864A3 (en) 2021-11-04
IL296239A (en) 2022-11-01
EP4114429A2 (en) 2023-01-11
WO2021178864A2 (en) 2021-09-10
CA3170752A1 (en) 2021-09-10
US20210275624A1 (en) 2021-09-09

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