MX2022007044A - Compuesto y composicion como inhibidor de cinasa del receptor de los factores de crecimiento derivados de las plaquetas (pdgf). - Google Patents

Compuesto y composicion como inhibidor de cinasa del receptor de los factores de crecimiento derivados de las plaquetas (pdgf).

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Publication number
MX2022007044A
MX2022007044A MX2022007044A MX2022007044A MX2022007044A MX 2022007044 A MX2022007044 A MX 2022007044A MX 2022007044 A MX2022007044 A MX 2022007044A MX 2022007044 A MX2022007044 A MX 2022007044A MX 2022007044 A MX2022007044 A MX 2022007044A
Authority
MX
Mexico
Prior art keywords
compound
receptor kinase
pdgf receptor
diseases
present
Prior art date
Application number
MX2022007044A
Other languages
English (en)
Inventor
Toru Tanaka
Yoshinari Haruta
Junshi Asada
Hiroyuki Yakushiji
Kazuya Kuramoto
Keiji Kosugi
Chiaki Fuchikami
Original Assignee
Nippon Shinyaku Co Ltd
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Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of MX2022007044A publication Critical patent/MX2022007044A/es

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Abstract

Un objeto de la presente invención es proporcionar un compuesto que tiene una actividad inhibidora de la cinasa del receptor de PDGF. Los ejemplos de la presente invención pueden incluir, por ejemplo, un compuesto representado por la siguiente fórmula [I] o una sal farmacéuticamente aceptable de este, o un solvato de este. (ver Fórmula) El compuesto de la presente invención tiene actividad inhibidora contra la cinasa del receptor de PDGF. Además, debido a que el compuesto de la presente invención tiene una actividad inhibidora contra el receptor cinasa de PDGF, es útil como agente terapéutico para enfermedades respiratorias, cánceres, enfermedades proliferativas del músculo liso, enfermedades vasoproliferativas, enfermedades autoinmunes/inflamatorias, enfermedades metabólicas, enfermedades vasooclusivas, y similares.
MX2022007044A 2019-12-13 2020-12-11 Compuesto y composicion como inhibidor de cinasa del receptor de los factores de crecimiento derivados de las plaquetas (pdgf). MX2022007044A (es)

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US20050014753A1 (en) * 2003-04-04 2005-01-20 Irm Llc Novel compounds and compositions as protein kinase inhibitors
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