MX2022007044A - Compuesto y composicion como inhibidor de cinasa del receptor de los factores de crecimiento derivados de las plaquetas (pdgf). - Google Patents
Compuesto y composicion como inhibidor de cinasa del receptor de los factores de crecimiento derivados de las plaquetas (pdgf).Info
- Publication number
- MX2022007044A MX2022007044A MX2022007044A MX2022007044A MX2022007044A MX 2022007044 A MX2022007044 A MX 2022007044A MX 2022007044 A MX2022007044 A MX 2022007044A MX 2022007044 A MX2022007044 A MX 2022007044A MX 2022007044 A MX2022007044 A MX 2022007044A
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- Prior art keywords
- compound
- receptor kinase
- pdgf receptor
- diseases
- present
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- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract
Un objeto de la presente invención es proporcionar un compuesto que tiene una actividad inhibidora de la cinasa del receptor de PDGF. Los ejemplos de la presente invención pueden incluir, por ejemplo, un compuesto representado por la siguiente fórmula [I] o una sal farmacéuticamente aceptable de este, o un solvato de este. (ver Fórmula) El compuesto de la presente invención tiene actividad inhibidora contra la cinasa del receptor de PDGF. Además, debido a que el compuesto de la presente invención tiene una actividad inhibidora contra el receptor cinasa de PDGF, es útil como agente terapéutico para enfermedades respiratorias, cánceres, enfermedades proliferativas del músculo liso, enfermedades vasoproliferativas, enfermedades autoinmunes/inflamatorias, enfermedades metabólicas, enfermedades vasooclusivas, y similares.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2019224959 | 2019-12-13 | ||
PCT/JP2020/046201 WO2021117846A1 (ja) | 2019-12-13 | 2020-12-11 | Pdgf受容体キナーゼ阻害剤としての化合物および組成物 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022007044A true MX2022007044A (es) | 2022-06-24 |
Family
ID=76329971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022007044A MX2022007044A (es) | 2019-12-13 | 2020-12-11 | Compuesto y composicion como inhibidor de cinasa del receptor de los factores de crecimiento derivados de las plaquetas (pdgf). |
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US (1) | US20230101484A1 (es) |
EP (1) | EP4074376A4 (es) |
JP (1) | JPWO2021117846A1 (es) |
KR (1) | KR20220115609A (es) |
CN (1) | CN115315421A (es) |
AR (1) | AR120723A1 (es) |
AU (1) | AU2020403681A1 (es) |
BR (1) | BR112022011017A2 (es) |
CA (1) | CA3164650A1 (es) |
CL (1) | CL2022001516A1 (es) |
CO (1) | CO2022008209A2 (es) |
EC (1) | ECSP22054240A (es) |
IL (1) | IL293836A (es) |
MX (1) | MX2022007044A (es) |
PE (1) | PE20221917A1 (es) |
TW (1) | TW202136234A (es) |
WO (1) | WO2021117846A1 (es) |
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Publication number | Priority date | Publication date | Assignee | Title |
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AU2021405620A1 (en) * | 2020-12-23 | 2023-06-29 | Actelion Pharmaceuticals Ltd | Pyrazolothiazole carboxamides and their uses as pdgfr inhibitors |
Family Cites Families (7)
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US20050014753A1 (en) * | 2003-04-04 | 2005-01-20 | Irm Llc | Novel compounds and compositions as protein kinase inhibitors |
US7259164B2 (en) * | 2003-08-11 | 2007-08-21 | Cgi Pharmaceuticals, Inc. | Certain substituted imidazo[1,2-a]pyrazines, as modulators of kinase activity |
US7968557B2 (en) * | 2004-02-14 | 2011-06-28 | Novartis Ag | Substituted pyrrolo[2,3-2]pyrimidines as protein kinase inhibitors |
US20100286211A1 (en) | 2004-10-08 | 2010-11-11 | Biswajit Das | Oxazolidinone derivatives as antimicrobials |
EP2937345B1 (en) * | 2009-12-29 | 2018-03-21 | Dana-Farber Cancer Institute, Inc. | Type ii raf kinase inhibitors |
EA201490542A1 (ru) * | 2011-09-01 | 2014-08-29 | АйАрЭм ЭлЭлСи | Соединения и композиции в качестве pdgfr киназных ингибиторов |
US8883819B2 (en) * | 2011-09-01 | 2014-11-11 | Irm Llc | Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension |
-
2020
- 2020-12-11 US US17/784,200 patent/US20230101484A1/en active Pending
- 2020-12-11 WO PCT/JP2020/046201 patent/WO2021117846A1/ja unknown
- 2020-12-11 BR BR112022011017A patent/BR112022011017A2/pt unknown
- 2020-12-11 CA CA3164650A patent/CA3164650A1/en active Pending
- 2020-12-11 CN CN202080086329.8A patent/CN115315421A/zh active Pending
- 2020-12-11 KR KR1020227024131A patent/KR20220115609A/ko unknown
- 2020-12-11 IL IL293836A patent/IL293836A/en unknown
- 2020-12-11 JP JP2021564049A patent/JPWO2021117846A1/ja active Pending
- 2020-12-11 MX MX2022007044A patent/MX2022007044A/es unknown
- 2020-12-11 TW TW109143902A patent/TW202136234A/zh unknown
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2022
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Also Published As
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CN115315421A (zh) | 2022-11-08 |
JPWO2021117846A1 (es) | 2021-06-17 |
CO2022008209A2 (es) | 2022-06-21 |
CA3164650A1 (en) | 2021-06-17 |
CL2022001516A1 (es) | 2023-03-24 |
WO2021117846A1 (ja) | 2021-06-17 |
AR120723A1 (es) | 2022-03-09 |
US20230101484A1 (en) | 2023-03-30 |
EP4074376A4 (en) | 2023-12-06 |
EP4074376A1 (en) | 2022-10-19 |
KR20220115609A (ko) | 2022-08-17 |
PE20221917A1 (es) | 2022-12-23 |
BR112022011017A2 (pt) | 2022-08-16 |
IL293836A (en) | 2022-08-01 |
ECSP22054240A (es) | 2022-08-31 |
AU2020403681A1 (en) | 2022-06-30 |
TW202136234A (zh) | 2021-10-01 |
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