MX2022005306A - Metodos y composiciones para uso de anticuerpos del factor de crecimiento en combinacion con inhibidores de cinasa dirigidos a no tirosinas. - Google Patents

Metodos y composiciones para uso de anticuerpos del factor de crecimiento en combinacion con inhibidores de cinasa dirigidos a no tirosinas.

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Publication number
MX2022005306A
MX2022005306A MX2022005306A MX2022005306A MX2022005306A MX 2022005306 A MX2022005306 A MX 2022005306A MX 2022005306 A MX2022005306 A MX 2022005306A MX 2022005306 A MX2022005306 A MX 2022005306A MX 2022005306 A MX2022005306 A MX 2022005306A
Authority
MX
Mexico
Prior art keywords
tyrosine
methods
combination
kinase inhibitors
compositions
Prior art date
Application number
MX2022005306A
Other languages
English (en)
Spanish (es)
Inventor
Miguel Ángel Molina-Villa
Erik D''HONDT
Original Assignee
In3Bio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by In3Bio Ltd filed Critical In3Bio Ltd
Publication of MX2022005306A publication Critical patent/MX2022005306A/es

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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1808—Epidermal growth factor [EGF] urogastrone
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
MX2022005306A 2019-11-07 2020-11-06 Metodos y composiciones para uso de anticuerpos del factor de crecimiento en combinacion con inhibidores de cinasa dirigidos a no tirosinas. MX2022005306A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962932131P 2019-11-07 2019-11-07
US202063094018P 2020-10-20 2020-10-20
PCT/IB2020/000969 WO2021090069A1 (en) 2019-11-07 2020-11-06 Methods and compositions for use of growth factor antibodies in combination with non-tyrosine targeting kinase inhibitors

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MX2022005306A true MX2022005306A (es) 2022-08-08

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US (1) US20220378891A1 (enExample)
EP (1) EP4054619A1 (enExample)
JP (1) JP2023500889A (enExample)
KR (1) KR20220099990A (enExample)
CN (1) CN115379851A (enExample)
AU (1) AU2020378682A1 (enExample)
BR (1) BR112022008704A2 (enExample)
CA (1) CA3157334A1 (enExample)
IL (1) IL292730A (enExample)
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WO2023159184A1 (en) * 2022-02-18 2023-08-24 Pattern Computer, Inc. Drug combinations and methods of treating ovarian cancer

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BR112014012460B1 (pt) 2011-11-23 2021-01-12 Bioven 3 Limited proteínas recombinantes
AU2013360335B2 (en) * 2012-12-13 2017-12-07 Immunomedics, Inc. Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
KR102391734B1 (ko) 2013-03-15 2022-04-29 인3바이오 리미티드 자기조립형 합성 단백질
EP3454864A4 (en) * 2016-04-21 2021-01-13 Abbvie Stemcentrx LLC Novel anti-bmpr1b antibodies and methods of use
JP2019536783A (ja) * 2016-11-30 2019-12-19 タイム，インコーポレーテッド チロシン誘導体及びそれらを含む組成物
CN110381997A (zh) * 2016-12-12 2019-10-25 茂体外尔公司 用于治疗和预防癌症和感染性疾病的包含病毒基因治疗和免疫检查点抑制剂的方法和组合物
WO2018175251A1 (en) * 2017-03-20 2018-09-27 Celcuity Llc Methods of measuring signaling pathway activity for selection of therapeutic agents
IL300235A (en) * 2017-07-18 2023-03-01 In3Bio Ltd Synthetic proteins and their therapeutic uses
AU2018329925B2 (en) * 2017-09-08 2025-05-29 F. Hoffmann-La Roche Ag Diagnostic and therapeutic methods for cancer

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BR112022008704A2 (pt) 2022-07-19
US20220378891A1 (en) 2022-12-01
WO2021090069A1 (en) 2021-05-14
KR20220099990A (ko) 2022-07-14
JP2023500889A (ja) 2023-01-11
AU2020378682A1 (en) 2022-06-23
CN115379851A (zh) 2022-11-22
EP4054619A1 (en) 2022-09-14
IL292730A (en) 2022-07-01
CA3157334A1 (en) 2021-05-14

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