MX2022004888A - (-)-cis tetrahidrocannabinol ((-)-cis-thc) para uso como medicamento. - Google Patents
(-)-cis tetrahidrocannabinol ((-)-cis-thc) para uso como medicamento.Info
- Publication number
- MX2022004888A MX2022004888A MX2022004888A MX2022004888A MX2022004888A MX 2022004888 A MX2022004888 A MX 2022004888A MX 2022004888 A MX2022004888 A MX 2022004888A MX 2022004888 A MX2022004888 A MX 2022004888A MX 2022004888 A MX2022004888 A MX 2022004888A
- Authority
- MX
- Mexico
- Prior art keywords
- thc
- cannabinoid
- cis
- tetrahydrocannabinol
- medicament
- Prior art date
Links
- 229960004242 dronabinol Drugs 0.000 title abstract 6
- CYQFCXCEBYINGO-UHFFFAOYSA-N THC Natural products C1=C(C)CCC2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3C21 CYQFCXCEBYINGO-UHFFFAOYSA-N 0.000 title abstract 5
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 title abstract 5
- 239000003814 drug Substances 0.000 title abstract 2
- 229930003827 cannabinoid Natural products 0.000 abstract 7
- 239000003557 cannabinoid Substances 0.000 abstract 7
- 241000218236 Cannabis Species 0.000 abstract 2
- QHMBSVQNZZTUGM-UHFFFAOYSA-N Trans-Cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-UHFFFAOYSA-N 0.000 abstract 2
- QHMBSVQNZZTUGM-ZWKOTPCHSA-N cannabidiol Chemical compound OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-ZWKOTPCHSA-N 0.000 abstract 2
- 229950011318 cannabidiol Drugs 0.000 abstract 2
- ZTGXAWYVTLUPDT-UHFFFAOYSA-N cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CC=C(C)C1 ZTGXAWYVTLUPDT-UHFFFAOYSA-N 0.000 abstract 2
- PCXRACLQFPRCBB-ZWKOTPCHSA-N dihydrocannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)C)CCC(C)=C1 PCXRACLQFPRCBB-ZWKOTPCHSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Pyrane Compounds (AREA)
Abstract
La presente invención se refiere a un compuesto cannabinoide de tipo tetrahidrocannabinol (THC) para uso como medicamento. El cannabinoide de tipo THC es un enantiómero del (-)-trans-tetrahidrocannabinol, que es un cannabinoide natural que se puede encontrar en las cepas de plantas de cannabis que han sido criadas para producir THC como cannabinoide dominante. Se ha descubierto que el enantiómero particular (-)-cis tetrahidrocannabinol tiene propiedades que son diferentes del (-)-trans-THC que ocurre de forma natural. Se ha descubierto que el cannabinoide (-)-cis-THC se encuentra en bajas concentraciones en determinadas cepas de plantas de cannabis que se han criado para producir cannabidiol (CBD) como cannabinoide dominante. Además, el cannabinoide se puede producir por medios sintéticos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1915513.4A GB2588455B (en) | 2019-10-25 | 2019-10-25 | Cannabinoid compound |
| PCT/GB2020/052678 WO2021079135A1 (en) | 2019-10-25 | 2020-10-23 | (-)-cis tetrahydrocannabinol ((-)-cis-thc) for use as a medicament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022004888A true MX2022004888A (es) | 2022-05-16 |
Family
ID=68769059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022004888A MX2022004888A (es) | 2019-10-25 | 2020-10-23 | (-)-cis tetrahidrocannabinol ((-)-cis-thc) para uso como medicamento. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220380334A1 (es) |
| EP (1) | EP4048253A1 (es) |
| JP (1) | JP2022553553A (es) |
| KR (1) | KR20220097424A (es) |
| CN (1) | CN114786663A (es) |
| AU (1) | AU2020371994A1 (es) |
| CA (1) | CA3155386A1 (es) |
| GB (1) | GB2588455B (es) |
| MX (1) | MX2022004888A (es) |
| TW (1) | TW202128147A (es) |
| WO (1) | WO2021079135A1 (es) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI436991B (zh) * | 2004-11-22 | 2014-05-11 | Euro Celtique Sa | 用於純化反-（-）-△９-四氫大麻酚與反-（＋）-△９-四氫大麻酚之方法 |
| US9254272B2 (en) * | 2011-11-30 | 2016-02-09 | Sutter West Bay Hospitals | Resorcinol derivatives |
| US9186386B2 (en) * | 2014-04-17 | 2015-11-17 | Gary J. Speier | Pharmaceutical composition and method of manufacturing |
| US20170348276A1 (en) * | 2016-06-02 | 2017-12-07 | Acerus Pharmaceutical Corporation | Nasal cannabidiol compositions |
| US10751380B2 (en) * | 2018-03-08 | 2020-08-25 | Alexander Kariman | Compound and method for treating spasms, inflammation and pain |
| GB201806953D0 (en) * | 2018-04-27 | 2018-06-13 | Gw Res Ltd | Cannabidiol Preparations |
-
2019
- 2019-10-25 GB GB1915513.4A patent/GB2588455B/en active Active
-
2020
- 2020-10-23 EP EP20800267.5A patent/EP4048253A1/en active Pending
- 2020-10-23 CN CN202080074337.0A patent/CN114786663A/zh active Pending
- 2020-10-23 WO PCT/GB2020/052678 patent/WO2021079135A1/en active Application Filing
- 2020-10-23 US US17/771,184 patent/US20220380334A1/en active Pending
- 2020-10-23 TW TW109136956A patent/TW202128147A/zh unknown
- 2020-10-23 MX MX2022004888A patent/MX2022004888A/es unknown
- 2020-10-23 JP JP2022523987A patent/JP2022553553A/ja active Pending
- 2020-10-23 CA CA3155386A patent/CA3155386A1/en active Pending
- 2020-10-23 KR KR1020227017473A patent/KR20220097424A/ko unknown
- 2020-10-23 AU AU2020371994A patent/AU2020371994A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2020371994A1 (en) | 2022-05-19 |
| GB201915513D0 (en) | 2019-12-11 |
| TW202128147A (zh) | 2021-08-01 |
| KR20220097424A (ko) | 2022-07-07 |
| CA3155386A1 (en) | 2021-04-29 |
| GB2588455B (en) | 2022-12-21 |
| US20220380334A1 (en) | 2022-12-01 |
| WO2021079135A1 (en) | 2021-04-29 |
| CN114786663A (zh) | 2022-07-22 |
| EP4048253A1 (en) | 2022-08-31 |
| GB2588455A (en) | 2021-04-28 |
| JP2022553553A (ja) | 2022-12-23 |
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