MX2022004888A - (-)-cis tetrahydrocannabinol ((-)-cis-thc) for use as a medicament. - Google Patents

(-)-cis tetrahydrocannabinol ((-)-cis-thc) for use as a medicament.

Info

Publication number
MX2022004888A
MX2022004888A MX2022004888A MX2022004888A MX2022004888A MX 2022004888 A MX2022004888 A MX 2022004888A MX 2022004888 A MX2022004888 A MX 2022004888A MX 2022004888 A MX2022004888 A MX 2022004888A MX 2022004888 A MX2022004888 A MX 2022004888A
Authority
MX
Mexico
Prior art keywords
thc
cannabinoid
cis
tetrahydrocannabinol
medicament
Prior art date
Application number
MX2022004888A
Other languages
Spanish (es)
Inventor
Geoffrey Guy
Benjamin Whalley
Volker Knappertz
Marie Woolley-Roberts
Original Assignee
Gw Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gw Res Ltd filed Critical Gw Res Ltd
Publication of MX2022004888A publication Critical patent/MX2022004888A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

The present invention relates to a tetrahydrocannabinol (THC) type cannabinoid compound for use as a medicament. The THC-type cannabinoid is an enantiomer of the (-)-trans- tetrahydrocannabinol which is a naturally occurring cannabinoid that can be found in cannabis plant strains which have been bred to yield THC as the dominant cannabinoid. The particular enantiomer (-)-cis tetrahydrocannabinol has been found to have properties which are different from the naturally occurring (-)-trans-THC. The cannabinoid (-)-cis-THC has been found to occur in low concentrations in particular cannabis plant strains which have been bred to produce cannabidiol (CBD) as the dominant cannabinoid. Furthermore, the cannabinoid can be produced by synthetic means.
MX2022004888A 2019-10-25 2020-10-23 (-)-cis tetrahydrocannabinol ((-)-cis-thc) for use as a medicament. MX2022004888A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1915513.4A GB2588455B (en) 2019-10-25 2019-10-25 Cannabinoid compound
PCT/GB2020/052678 WO2021079135A1 (en) 2019-10-25 2020-10-23 (-)-cis tetrahydrocannabinol ((-)-cis-thc) for use as a medicament

Publications (1)

Publication Number Publication Date
MX2022004888A true MX2022004888A (en) 2022-05-16

Family

ID=68769059

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022004888A MX2022004888A (en) 2019-10-25 2020-10-23 (-)-cis tetrahydrocannabinol ((-)-cis-thc) for use as a medicament.

Country Status (11)

Country Link
US (1) US20220380334A1 (en)
EP (1) EP4048253A1 (en)
JP (1) JP2022553553A (en)
KR (1) KR20220097424A (en)
CN (1) CN114786663A (en)
AU (1) AU2020371994A1 (en)
CA (1) CA3155386A1 (en)
GB (1) GB2588455B (en)
MX (1) MX2022004888A (en)
TW (1) TW202128147A (en)
WO (1) WO2021079135A1 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI369203B (en) * 2004-11-22 2012-08-01 Euro Celtique Sa Methods for purifying trans-(-)-△9-tetrahydrocannabinol and trans-(+)-△9-tetrahydrocannabinol
US9254272B2 (en) * 2011-11-30 2016-02-09 Sutter West Bay Hospitals Resorcinol derivatives
US9186386B2 (en) * 2014-04-17 2015-11-17 Gary J. Speier Pharmaceutical composition and method of manufacturing
US20170348276A1 (en) * 2016-06-02 2017-12-07 Acerus Pharmaceutical Corporation Nasal cannabidiol compositions
US10751380B2 (en) * 2018-03-08 2020-08-25 Alexander Kariman Compound and method for treating spasms, inflammation and pain
GB201806953D0 (en) * 2018-04-27 2018-06-13 Gw Res Ltd Cannabidiol Preparations

Also Published As

Publication number Publication date
CA3155386A1 (en) 2021-04-29
US20220380334A1 (en) 2022-12-01
TW202128147A (en) 2021-08-01
AU2020371994A1 (en) 2022-05-19
GB2588455B (en) 2022-12-21
JP2022553553A (en) 2022-12-23
KR20220097424A (en) 2022-07-07
CN114786663A (en) 2022-07-22
WO2021079135A1 (en) 2021-04-29
GB2588455A (en) 2021-04-28
GB201915513D0 (en) 2019-12-11
EP4048253A1 (en) 2022-08-31

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