MX2022004274A - Las sales de un compuesto y sus formas cristalinas. - Google Patents

Las sales de un compuesto y sus formas cristalinas.

Info

Publication number
MX2022004274A
MX2022004274A MX2022004274A MX2022004274A MX2022004274A MX 2022004274 A MX2022004274 A MX 2022004274A MX 2022004274 A MX2022004274 A MX 2022004274A MX 2022004274 A MX2022004274 A MX 2022004274A MX 2022004274 A MX2022004274 A MX 2022004274A
Authority
MX
Mexico
Prior art keywords
compound
crystalline forms
salts
same
present
Prior art date
Application number
MX2022004274A
Other languages
English (en)
Spanish (es)
Inventor
Wenji Li
Ling Feng
Original Assignee
Hutchison Medipharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hutchison Medipharma Ltd filed Critical Hutchison Medipharma Ltd
Publication of MX2022004274A publication Critical patent/MX2022004274A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185Saturated compounds having only one carboxyl group and containing keto groups
    • C07C59/225Saturated compounds having only one carboxyl group and containing keto groups containing —CHO groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX2022004274A 2019-10-14 2020-10-13 Las sales de un compuesto y sus formas cristalinas. MX2022004274A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201910973785 2019-10-14
PCT/CN2020/120594 WO2021073494A1 (en) 2019-10-14 2020-10-13 The salts of a compound and the crystalline forms thereof

Publications (1)

Publication Number Publication Date
MX2022004274A true MX2022004274A (es) 2022-05-06

Family

ID=75537486

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022004274A MX2022004274A (es) 2019-10-14 2020-10-13 Las sales de un compuesto y sus formas cristalinas.

Country Status (14)

Country Link
US (1) US12559472B2 (https=)
EP (1) EP4045484A4 (https=)
JP (2) JP2022552329A (https=)
KR (1) KR20220088712A (https=)
CN (3) CN119751422A (https=)
AR (1) AR120202A1 (https=)
AU (1) AU2020367905A1 (https=)
BR (1) BR112022007035A2 (https=)
CA (1) CA3154064A1 (https=)
IL (1) IL292206B2 (https=)
MX (1) MX2022004274A (https=)
TW (1) TWI895290B (https=)
UA (1) UA129777C2 (https=)
WO (1) WO2021073494A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7736357B2 (ja) * 2021-12-13 2025-09-09 アビスコ セラピューティクス カンパニー リミテッド Fgfr4阻害剤酸性塩およびその製造方法と使用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR079257A1 (es) * 2009-12-07 2012-01-04 Novartis Ag Formas cristalinas de 3-(2,6-dicloro-3-5-dimetoxi-fenil)-1-{6-[4-(4-etil-piperazin-1-il)-fenil-amino]-pirimidin-4-il}-1-metil-urea y sales de las mismas
WO2014139145A1 (en) * 2013-03-15 2014-09-18 Hutchison Medipharma Limited Novel pyrimidine and pyridine compounds and usage thereof
KR102548229B1 (ko) * 2015-04-14 2023-06-27 에자이 알앤드디 매니지먼트 가부시키가이샤 결정질 fgfr4 억제제 화합물 및 그의 용도
WO2018099451A1 (zh) 2016-12-01 2018-06-07 和记黄埔医药(上海)有限公司 化合物的晶型

Also Published As

Publication number Publication date
CN114555558A (zh) 2022-05-27
US20230121346A1 (en) 2023-04-20
TWI895290B (zh) 2025-09-01
UA129777C2 (uk) 2025-07-30
AU2020367905A1 (en) 2022-04-21
EP4045484A1 (en) 2022-08-24
IL292206B2 (en) 2026-03-01
CN114555558B (zh) 2024-12-17
US12559472B2 (en) 2026-02-24
TW202128669A (zh) 2021-08-01
AR120202A1 (es) 2022-02-02
EP4045484A4 (en) 2023-09-06
CN119462616A (zh) 2025-02-18
WO2021073494A1 (en) 2021-04-22
CA3154064A1 (en) 2021-04-22
JP2025143319A (ja) 2025-10-01
KR20220088712A (ko) 2022-06-28
IL292206A (en) 2022-06-01
JP2022552329A (ja) 2022-12-15
IL292206B1 (en) 2025-11-01
CN119751422A (zh) 2025-04-04
BR112022007035A2 (pt) 2022-06-28

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