MX2021014028A - Métodos y composiciones para tratar obesidad y/o trastornos de la piel. - Google Patents
Métodos y composiciones para tratar obesidad y/o trastornos de la piel.Info
- Publication number
- MX2021014028A MX2021014028A MX2021014028A MX2021014028A MX2021014028A MX 2021014028 A MX2021014028 A MX 2021014028A MX 2021014028 A MX2021014028 A MX 2021014028A MX 2021014028 A MX2021014028 A MX 2021014028A MX 2021014028 A MX2021014028 A MX 2021014028A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- methods
- tslp
- treating obesity
- skin disorders
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14171—Demonstrated in vivo effect
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Child & Adolescent Psychology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Mycology (AREA)
- Ophthalmology & Optometry (AREA)
Abstract
Se proporcionan composiciones y métodos para tratar obesidad; en ciertas modalidades, las composiciones comprenden el derivado de vitamina D3 tópico MC903; en otras modalidades, las composiciones incrementan sistémicamente los niveles de TSLP en un sujeto; en aún otras modalidades, las composiciones incluyen isoformas del péptido de TSLP y/o vectores virales adeno-asociados que contienen secuencias que expresan TSLP; los métodos que usan estas composiciones incrementan los niveles de TSLP en el sujeto y causan la pérdida selectiva de tejido adiposo blanco sin la pérdida de masa muscular.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962849656P | 2019-05-17 | 2019-05-17 | |
US202062972462P | 2020-02-10 | 2020-02-10 | |
PCT/US2020/033415 WO2020236722A1 (en) | 2019-05-17 | 2020-05-18 | Methods and compositions for treating obesity and/or skin disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021014028A true MX2021014028A (es) | 2022-02-21 |
Family
ID=73459398
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021014028A MX2021014028A (es) | 2019-05-17 | 2020-05-18 | Métodos y composiciones para tratar obesidad y/o trastornos de la piel. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20220233641A1 (es) |
EP (1) | EP3969005A4 (es) |
JP (1) | JP2022533157A (es) |
KR (1) | KR20220034042A (es) |
CN (1) | CN114126623A (es) |
AU (1) | AU2020279960A1 (es) |
BR (1) | BR112021023035A2 (es) |
CA (1) | CA3140952A1 (es) |
MX (1) | MX2021014028A (es) |
WO (1) | WO2020236722A1 (es) |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19519273A1 (de) * | 1995-05-22 | 1996-11-28 | Schering Ag | Topisch applizierbare Mittel zur Behandlung und Prophylaxe der Alopezie |
JPH10316574A (ja) * | 1997-05-16 | 1998-12-02 | Santen Pharmaceut Co Ltd | ドライアイ治療剤 |
WO1998053806A1 (fr) * | 1997-05-26 | 1998-12-03 | New Vision Co., Ltd. | Compositions medicinales a administration topique renfermant les vitamines d et les vitamines k |
US6187331B1 (en) * | 1997-06-10 | 2001-02-13 | New Vision Co., Ltd. | Composition for prophylaxis and/or treatment of dry syndrome comprising vitamin D |
AU2004273672A1 (en) * | 2003-09-19 | 2005-03-31 | Wisconsin Alumni Research Foundation | Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin D derivatives and a bisphosphonate |
CN101217868A (zh) * | 2005-05-10 | 2008-07-09 | 德米普瑟尔有限公司 | 用于皮肤护理的组合物和方法 |
BRPI0920430A2 (pt) * | 2008-10-22 | 2019-09-24 | Revalesio Corp | composições e métodos para tratar condições mediadas por metaloproteinase matriz 9 (mmp9) |
CN102655869B (zh) * | 2009-08-14 | 2016-08-10 | 博格有限责任公司 | 用于治疗脱发的维生素d3及其类似物 |
BR112017004893A2 (pt) * | 2014-09-10 | 2017-12-12 | Univ Washington | composições e métodos para o tratamento de lesões cutâneas pré-cancerosas |
WO2016103722A1 (en) * | 2014-12-24 | 2016-06-30 | Kyoto University | Vitamin d3 derivatives and pharmaceutical use thereof |
US10391107B2 (en) * | 2015-03-16 | 2019-08-27 | The Trustees Of The University Of Pennsylvania | Compositions and methods for suppressing or reducing systemic immune response in a subject |
WO2017017677A1 (en) * | 2015-07-27 | 2017-02-02 | Galmed Research And Development Ltd. | Combination treatment for liver disease |
CN108853503A (zh) * | 2017-05-11 | 2018-11-23 | 中国科学院水生生物研究所 | 维生素d受体激动剂用于预防和/或治疗肥胖的用途 |
CN109432211B (zh) * | 2019-01-03 | 2021-06-15 | 北京市中医研究所 | 用于银屑病和湿疹的中药组合物及其外用药物以及二者的制备方法和应用 |
-
2020
- 2020-05-18 MX MX2021014028A patent/MX2021014028A/es unknown
- 2020-05-18 BR BR112021023035A patent/BR112021023035A2/pt unknown
- 2020-05-18 KR KR1020217041197A patent/KR20220034042A/ko unknown
- 2020-05-18 US US17/611,309 patent/US20220233641A1/en active Pending
- 2020-05-18 WO PCT/US2020/033415 patent/WO2020236722A1/en active Application Filing
- 2020-05-18 CA CA3140952A patent/CA3140952A1/en active Pending
- 2020-05-18 CN CN202080051286.XA patent/CN114126623A/zh active Pending
- 2020-05-18 AU AU2020279960A patent/AU2020279960A1/en active Pending
- 2020-05-18 JP JP2021568506A patent/JP2022533157A/ja active Pending
- 2020-05-18 EP EP20808984.7A patent/EP3969005A4/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CA3140952A1 (en) | 2020-11-26 |
AU2020279960A1 (en) | 2021-12-23 |
JP2022533157A (ja) | 2022-07-21 |
KR20220034042A (ko) | 2022-03-17 |
EP3969005A1 (en) | 2022-03-23 |
BR112021023035A2 (pt) | 2022-01-25 |
US20220233641A1 (en) | 2022-07-28 |
WO2020236722A1 (en) | 2020-11-26 |
EP3969005A4 (en) | 2023-10-04 |
CN114126623A (zh) | 2022-03-01 |
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