MX2021009831A - Anticuerpos claudina 6 y usos de los mismos. - Google Patents
Anticuerpos claudina 6 y usos de los mismos.Info
- Publication number
- MX2021009831A MX2021009831A MX2021009831A MX2021009831A MX2021009831A MX 2021009831 A MX2021009831 A MX 2021009831A MX 2021009831 A MX2021009831 A MX 2021009831A MX 2021009831 A MX2021009831 A MX 2021009831A MX 2021009831 A MX2021009831 A MX 2021009831A
- Authority
- MX
- Mexico
- Prior art keywords
- antibodies
- claudin
- compositions against
- against claudin
- compositions
- Prior art date
Links
- 102000003859 Claudin-6 Human genes 0.000 title abstract 2
- 108090000229 Claudin-6 Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/463—Cellular immunotherapy characterised by recombinant expression
- A61K39/4631—Chimeric Antigen Receptors [CAR]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464402—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se proporcionan anticuerpos y composiciones contra claudina 6 y usos de los mismos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962806048P | 2019-02-15 | 2019-02-15 | |
PCT/US2020/018087 WO2020168059A1 (en) | 2019-02-15 | 2020-02-13 | Claudin 6 antibodies and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021009831A true MX2021009831A (es) | 2021-09-10 |
Family
ID=72043303
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021009831A MX2021009831A (es) | 2019-02-15 | 2020-02-13 | Anticuerpos claudina 6 y usos de los mismos. |
Country Status (19)
Country | Link |
---|---|
US (2) | US11248046B2 (es) |
EP (1) | EP3924389A4 (es) |
JP (1) | JP2022521723A (es) |
KR (1) | KR20210128443A (es) |
CN (1) | CN113767113A (es) |
AU (1) | AU2020223293A1 (es) |
BR (1) | BR112021016056A2 (es) |
CA (1) | CA3129834A1 (es) |
CL (1) | CL2021002141A1 (es) |
CO (1) | CO2021011906A2 (es) |
CR (1) | CR20210471A (es) |
EA (1) | EA202192146A1 (es) |
EC (1) | ECSP21068097A (es) |
IL (1) | IL285626A (es) |
MA (1) | MA54955A (es) |
MX (1) | MX2021009831A (es) |
SG (1) | SG11202108281UA (es) |
WO (1) | WO2020168059A1 (es) |
ZA (1) | ZA202106602B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CR20210471A (es) | 2019-02-15 | 2021-12-08 | Integral Molecular Inc | Anticuerpos claudina 6 y usos de los mismos |
JP2022520632A (ja) | 2019-02-15 | 2022-03-31 | インテグラル・モレキュラー・インコーポレイテッド | 共通軽鎖を含む抗体及びその使用 |
JP2024508304A (ja) * | 2021-03-02 | 2024-02-26 | ノヴァロック バイオセラピューティクス, リミテッド | Claudin-6に対する抗体およびそれの使用 |
JPWO2023053282A1 (es) * | 2021-09-29 | 2023-04-06 | ||
WO2023230624A2 (en) * | 2022-05-27 | 2023-11-30 | Taipei Medical University | Epha2-targeting antibodies and their applications in cancer treatment |
Family Cites Families (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
US4699880A (en) | 1984-09-25 | 1987-10-13 | Immunomedics, Inc. | Method of producing monoclonal anti-idiotype antibody |
JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
DE3689123T2 (de) | 1985-11-01 | 1994-03-03 | Xoma Corp | Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung. |
WO1988001649A1 (en) | 1986-09-02 | 1988-03-10 | Genex Corporation | Single polypeptide chain binding molecules |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
DK0786469T3 (da) | 1990-06-11 | 2006-07-10 | Gilead Sciences Inc | Nukleinsyreligander |
WO1993011161A1 (en) | 1991-11-25 | 1993-06-10 | Enzon, Inc. | Multivalent antigen-binding proteins |
US6005079A (en) | 1992-08-21 | 1999-12-21 | Vrije Universiteit Brussels | Immunoglobulins devoid of light chains |
PT1498427E (pt) | 1992-08-21 | 2010-03-22 | Univ Bruxelles | Imunoglobulinas desprovidas de cadeias leves |
US6838254B1 (en) | 1993-04-29 | 2005-01-04 | Conopco, Inc. | Production of antibodies or (functionalized) fragments thereof derived from heavy chain immunoglobulins of camelidae |
SE9400088D0 (sv) | 1994-01-14 | 1994-01-14 | Kabi Pharmacia Ab | Bacterial receptor structures |
EP1405911A1 (en) | 1994-07-20 | 2004-04-07 | The General Hospital Corporation | Interaction trap systems for detecting protein interactions |
US7763258B2 (en) | 1997-05-20 | 2010-07-27 | The Trustees Of The University Of Pennsylvania | Virus-like particles (VLPs) comprising heterologous multiple membrane spanning proteins |
DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
AUPP221098A0 (en) | 1998-03-06 | 1998-04-02 | Diatech Pty Ltd | V-like domain binding molecules |
US6955807B1 (en) | 1998-05-15 | 2005-10-18 | Bayer Pharmaceuticals Corporation | IL-2 selective agonists and antagonists |
US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
US6994982B1 (en) | 1999-05-05 | 2006-02-07 | Phylogica Limited | Isolating biological modulators from biodiverse gene fragment libraries |
WO2000072742A2 (en) | 1999-05-26 | 2000-12-07 | Kalle Saksela | Methods and materials for generating sh3 domains with tailored binding properties |
SE0001877D0 (sv) | 2000-05-22 | 2000-05-22 | Klaus Mosbach | Molecular imprinting |
AU2002218166A1 (en) | 2000-09-08 | 2002-03-22 | Universitat Zurich | Collections of repeat proteins comprising repeat modules |
DE10053224A1 (de) | 2000-10-26 | 2002-05-08 | Univ Goettingen Georg August | Verfahren zur Exposition von Peptiden und Polypeptiden auf der Zelloberfläche von Bakterien |
EP2284270A3 (en) | 2000-12-13 | 2012-07-25 | Anaphore, Inc. | Method for the identification and isolation of binding polypeptides from combinatorial libraries of proteins having the scaffold structure of C-type lectin-like domains |
AUPR546801A0 (en) * | 2001-06-05 | 2001-06-28 | Commonwealth Scientific And Industrial Research Organisation | Recombinant antibodies |
AU2002323501C1 (en) | 2001-08-30 | 2010-04-29 | Biorexis Technology, Inc | Modified transferrin fusion proteins |
JP5376747B2 (ja) | 2002-10-02 | 2013-12-25 | カタリスト バイオサイエンシーズ, インコーポレイテッド | 改変された特異性を有するプロテアーゼを作製する方法およびスクリーニングする方法 |
ES2362424T3 (es) | 2003-01-07 | 2011-07-05 | Dyax Corporation | Biblioteca del dominio kunitz. |
US8574590B2 (en) | 2003-07-30 | 2013-11-05 | Integral Molecular, Inc. | Lipoparticles comprising proteins, methods of making, and using the same |
JP2007527242A (ja) | 2004-03-05 | 2007-09-27 | カイロン コーポレーション | 治療剤の患者耐容性を予測するためのインビトロ試験システム |
US20060008844A1 (en) | 2004-06-17 | 2006-01-12 | Avidia Research Institute | c-Met kinase binding proteins |
DE102004049479A1 (de) | 2004-10-11 | 2006-04-13 | Scil Proteins Gmbh | Proteinkonjugate zur Verwendung in Therapie, Diagnose und Chromatographie |
US8367805B2 (en) | 2004-11-12 | 2013-02-05 | Xencor, Inc. | Fc variants with altered binding to FcRn |
US8377691B2 (en) | 2006-01-26 | 2013-02-19 | Integral Molecular, Inc. | Lipoparticles comprising ion channels, methods of making and using the same |
EP1892248A1 (en) | 2006-08-21 | 2008-02-27 | Eidgenössische Technische Hochschule Zürich | Specific and high affinity binding proteins comprising modified SH3 domains of FYN kinase |
GB0624500D0 (en) * | 2006-12-07 | 2007-01-17 | Istituto Superiore Di Sanito | A novel passive vaccine for candida infections |
CN103897063B (zh) | 2007-06-01 | 2017-04-12 | 马里兰大学巴尔的摩分校 | 免疫球蛋白恒定区Fc受体结合剂 |
WO2009025759A1 (en) | 2007-08-17 | 2009-02-26 | Progenics Pharmaceuticals (Nevada), Inc. | Tight junction proteins associated with infection and entry of hepatitis c virus (hcv), methods and uses thereof |
US9274119B2 (en) | 2008-01-11 | 2016-03-01 | The University Of Tokyo | Anti-CLDN6 antibody |
JP5766124B2 (ja) | 2009-01-21 | 2015-08-19 | アムジェン インコーポレイテッド | 炎症性疾患および自己免疫疾患の処置の組成物および方法 |
WO2010126590A1 (en) * | 2009-04-27 | 2010-11-04 | Cold Spring Harbor Laboratory | Ptp1b inhibitors |
CA2775373C (en) | 2009-11-11 | 2019-10-29 | Ganymed Pharmaceuticals Ag | Antibodies specific for claudin 6 (cldn6) |
EP2322555A1 (en) * | 2009-11-11 | 2011-05-18 | Ganymed Pharmaceuticals AG | Antibodies specific for claudin 6 (CLDN6) |
JP5742714B2 (ja) | 2010-02-04 | 2015-07-01 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
EP2404936A1 (en) * | 2010-07-06 | 2012-01-11 | Ganymed Pharmaceuticals AG | Cancer therapy using CLDN6 target-directed antibodies in vivo |
EP3211001B1 (en) | 2010-12-22 | 2020-10-07 | The Board of Trustees of the Leland Stanford Junior University | Superagonists and antagonists of interleukin-2 |
CN107090043B (zh) * | 2011-05-13 | 2021-12-07 | 加尼梅德药物公司 | 用于治疗表达密蛋白6之癌症的抗体 |
EP2766785B1 (en) | 2011-10-14 | 2019-03-13 | Ergotron, Inc. | Tablet mounting arm systems and methods |
US9636381B2 (en) | 2012-01-18 | 2017-05-02 | Neumedicines, Inc. | Methods for radiation protection by administering IL-12 |
WO2014016737A1 (en) | 2012-07-24 | 2014-01-30 | Pfizer Inc. | Novel chicken monoclonal antibodies against human phosphorylated tau and uses thereof |
US9546203B2 (en) | 2013-03-14 | 2017-01-17 | Amgen Inc. | Aglycosylated Fc-containing polypeptides with cysteine substitutions |
WO2015014376A1 (en) | 2013-07-31 | 2015-02-05 | Biontech Ag | Diagnosis and therapy of cancer involving cancer stem cells |
CN103483449A (zh) * | 2013-08-20 | 2014-01-01 | 东北农业大学 | 两种scFv抗体、其编码基因及其在制备治疗或预防鸡传染性法氏囊病制剂中的应用 |
MX2016005763A (es) | 2013-11-06 | 2016-08-19 | Stemcentrx Inc | Anticuerpos anti-claudina novedosos y metodos de uso. |
CN114133456A (zh) | 2014-07-21 | 2022-03-04 | 德里尼亚公司 | 选择性地活化调节性t细胞用于治疗自身免疫病的分子 |
PL3482766T3 (pl) | 2014-08-11 | 2020-11-16 | Delinia, Inc. | Modyfikowane warianty il-2, które selektywnie aktywują limfocyty t regulatorowe do leczenia chorób autoimmunologicznych |
CA2874083C (en) * | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
ES2952132T3 (es) | 2015-03-06 | 2023-10-27 | Public Univ Corp Yokohama City Univ | Nuevo anticuerpo anti-pad4 |
GB201607534D0 (en) | 2016-04-29 | 2016-06-15 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
AU2016364853A1 (en) * | 2015-12-04 | 2018-06-21 | Abbvie Stemcentrx Llc | Novel anti-claudin antibodies and methods of use |
US11597763B2 (en) * | 2016-05-02 | 2023-03-07 | Tetragenetics, Inc. | Anti-Kv1.3 antibodies, and methods of production and use thereof |
CN115073581A (zh) | 2016-05-04 | 2022-09-20 | 美国安进公司 | 用于扩增t调节性细胞的白细胞介素-2突变蛋白 |
WO2018054484A1 (en) | 2016-09-23 | 2018-03-29 | Biontech Ag | Bispecific trivalent antibodies binding to claudin 6 or claudin18.2 and cd3 for treatment of claudin expressing cancer diseases |
WO2018067198A1 (en) * | 2016-10-03 | 2018-04-12 | The Regents Of The University Of California | Inhibitory antibodies and methods of use thereof |
WO2019048040A1 (en) | 2017-09-06 | 2019-03-14 | Ganymed Pharmaceuticals Gmbh | ANTIBODIES USEFUL IN THE DIAGNOSIS OF CANCER |
SG11202002114RA (en) | 2017-09-18 | 2020-04-29 | Univ California | Claudin6 antibodies and methods of treating cancer |
US20220018842A1 (en) | 2018-10-09 | 2022-01-20 | Fukushima Medical University | A biomarker for predicting the prognosis for an endometrial cancer patient |
CR20210471A (es) | 2019-02-15 | 2021-12-08 | Integral Molecular Inc | Anticuerpos claudina 6 y usos de los mismos |
JP2022520632A (ja) | 2019-02-15 | 2022-03-31 | インテグラル・モレキュラー・インコーポレイテッド | 共通軽鎖を含む抗体及びその使用 |
KR20210154158A (ko) | 2019-03-20 | 2021-12-20 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 클라우딘-6 항체 및 약물 컨쥬게이트 |
BR112021023173A2 (pt) | 2019-07-10 | 2022-01-04 | Chugai Pharmaceutical Co Ltd | Moléculas de ligação à claudin-6 e usos das mesmas |
-
2020
- 2020-02-13 CR CR20210471A patent/CR20210471A/es unknown
- 2020-02-13 EA EA202192146A patent/EA202192146A1/ru unknown
- 2020-02-13 AU AU2020223293A patent/AU2020223293A1/en active Pending
- 2020-02-13 MX MX2021009831A patent/MX2021009831A/es unknown
- 2020-02-13 JP JP2021547877A patent/JP2022521723A/ja active Pending
- 2020-02-13 SG SG11202108281UA patent/SG11202108281UA/en unknown
- 2020-02-13 CA CA3129834A patent/CA3129834A1/en active Pending
- 2020-02-13 US US16/790,066 patent/US11248046B2/en active Active
- 2020-02-13 MA MA054955A patent/MA54955A/fr unknown
- 2020-02-13 BR BR112021016056A patent/BR112021016056A2/pt unknown
- 2020-02-13 CN CN202080025731.5A patent/CN113767113A/zh active Pending
- 2020-02-13 KR KR1020217029523A patent/KR20210128443A/ko unknown
- 2020-02-13 EP EP20755889.1A patent/EP3924389A4/en active Pending
- 2020-02-13 WO PCT/US2020/018087 patent/WO2020168059A1/en active Application Filing
-
2021
- 2021-08-12 CL CL2021002141A patent/CL2021002141A1/es unknown
- 2021-08-15 IL IL285626A patent/IL285626A/en unknown
- 2021-09-08 ZA ZA2021/06602A patent/ZA202106602B/en unknown
- 2021-09-10 CO CONC2021/0011906A patent/CO2021011906A2/es unknown
- 2021-09-14 EC ECSENADI202168097A patent/ECSP21068097A/es unknown
-
2022
- 2022-01-04 US US17/568,438 patent/US20220127355A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2022521723A (ja) | 2022-04-12 |
AU2020223293A1 (en) | 2021-08-19 |
CA3129834A1 (en) | 2020-08-20 |
CL2021002141A1 (es) | 2022-04-01 |
EA202192146A1 (ru) | 2021-11-09 |
US11248046B2 (en) | 2022-02-15 |
BR112021016056A2 (pt) | 2021-12-14 |
EP3924389A1 (en) | 2021-12-22 |
CO2021011906A2 (es) | 2021-09-30 |
WO2020168059A1 (en) | 2020-08-20 |
EP3924389A4 (en) | 2023-06-14 |
CN113767113A (zh) | 2021-12-07 |
CR20210471A (es) | 2021-12-08 |
ZA202106602B (en) | 2023-12-20 |
US20220127355A1 (en) | 2022-04-28 |
US20200262915A1 (en) | 2020-08-20 |
SG11202108281UA (en) | 2021-08-30 |
KR20210128443A (ko) | 2021-10-26 |
ECSP21068097A (es) | 2021-11-18 |
MA54955A (fr) | 2021-12-22 |
IL285626A (en) | 2021-09-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA202106602B (en) | Claudin 6 antibodies and uses thereof | |
EP3794037A4 (en) | ANTI-CLAUDIN 18.2 ANTIBODIES AND USES THEREOF | |
EP3762031A4 (en) | ANTI-CLAUDINE ANTIBODIES 18.2 AND THEIR USES | |
PH12020500398A1 (en) | Antibody-pyrrolobenzodiazepine derivative conjugate | |
WO2018109174A3 (en) | Il-11 antibodies | |
WO2018109170A3 (en) | Il-11ra antibodies | |
MX2022002111A (es) | Novedosos anticuerpos anti-cldn18.2. | |
JOP20200074A1 (ar) | أجسام مضادة ضد tau واستخداماتها | |
IL283754A (en) | Anti-claudin antibodies, preparations containing them and their uses | |
MX2021008592A (es) | Composiciones de trem y usos de las mismas. | |
MX2021013417A (es) | Polipeptidos de union a la proteina del miembro a de la familia 12 del dominio de lectina tipo c (clec12a) y sus usos. | |
PH12020551716A1 (en) | Anti-ror antibody constructs | |
IL285651A (en) | Anti-trem2 antibodies, preparations containing them and their uses | |
AU2019321490A8 (en) | Ox40-binding polypeptides and uses thereof | |
MX2022007841A (es) | Degradadores del regulador dependiente de actina asociado a la matriz relacionado con el complejo switch/sacarosa no fermentable de la subfamilia a de la cromatina (smarca)y usos de los mismos. | |
MX2018012797A (es) | Inhibidores de erbb y usos de los mismos. | |
WO2020104970A3 (en) | Multi-layered particles | |
GB202017595D0 (en) | Compositions, and methods and uses relating thereto | |
EP3883967A4 (en) | ANTI-CD38 AND ANTI-ICAM1 ANTIBODIES AND THEIR USES | |
EP3880828A4 (en) | PLANT VECTORS, COMPOSITIONS AND ASSOCIATED USES | |
ZA202205738B (en) | Tumor-specific claudin 18.2 antibodies | |
EP4093764A4 (en) | MULTI-SPECIFIC ANTIBODIES, COMPOSITIONS THEREOF AND VECTORS AND USES THEREOF | |
IL310535A (en) | Anti-GDF15 antibodies, compositions and uses thereof | |
GB201909298D0 (en) | Novel compositions and uses thereof | |
SG11201900709QA (en) | Mixed cement |