MX2021004883A - Metodos y composiciones para tratar apnea del sue?o. - Google Patents
Metodos y composiciones para tratar apnea del sue?o.Info
- Publication number
- MX2021004883A MX2021004883A MX2021004883A MX2021004883A MX2021004883A MX 2021004883 A MX2021004883 A MX 2021004883A MX 2021004883 A MX2021004883 A MX 2021004883A MX 2021004883 A MX2021004883 A MX 2021004883A MX 2021004883 A MX2021004883 A MX 2021004883A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- sleep apnea
- compositions
- treating sleep
- hydroxyatomoxetine
- Prior art date
Links
- 201000002859 sleep apnea Diseases 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- PPXQPRLGNSJNJM-QGZVFWFLSA-N 4-Hydroxyatomoxetine Chemical compound O([C@H](CCNC)C=1C=CC=CC=1)C1=CC=C(O)C=C1C PPXQPRLGNSJNJM-QGZVFWFLSA-N 0.000 abstract 3
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 abstract 3
- 239000003149 muscarinic antagonist Substances 0.000 abstract 3
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862753420P | 2018-10-31 | 2018-10-31 | |
| PCT/US2019/043065 WO2020091862A1 (en) | 2018-10-31 | 2019-07-23 | Methods and compositions for treating sleep apnea |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021004883A true MX2021004883A (es) | 2021-08-05 |
Family
ID=67539629
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021004883A MX2021004883A (es) | 2018-10-31 | 2019-07-23 | Metodos y composiciones para tratar apnea del sue?o. |
| MX2024013184A MX2024013184A (es) | 2018-10-31 | 2021-04-28 | Metodos y composiciones para tratar apnea del sue?o |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2024013184A MX2024013184A (es) | 2018-10-31 | 2021-04-28 | Metodos y composiciones para tratar apnea del sue?o |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20210401790A1 (https=) |
| EP (1) | EP3873454A1 (https=) |
| JP (2) | JP2022506113A (https=) |
| KR (1) | KR20210084481A (https=) |
| CN (1) | CN112930179A (https=) |
| AU (1) | AU2019370091A1 (https=) |
| CA (1) | CA3117766A1 (https=) |
| MX (2) | MX2021004883A (https=) |
| WO (1) | WO2020091862A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240021920A (ko) * | 2021-06-17 | 2024-02-19 | 애프니메드, 인코포레이티드 (델라웨어) | 수면 무호흡증을 치료하기 위한 노르에피네프린 재흡수 억제제 |
| MX2024007764A (es) * | 2021-12-22 | 2024-07-04 | Bayer Ag | Combinacion de un bloqueante de canales task1/3 con un inhibidor de la recaptacion de norepinefrina para el tratamiento de la apnea del sue?o. |
| US20250049779A1 (en) * | 2021-12-22 | 2025-02-13 | Bayer Aktiengesellschaft | Combination of an a2-adrenoceptor subtype c (alpha-2c) antagonist with a norepinephrine reuptake inhibitor for the treatment of sleep apnea |
| CN119789855A (zh) * | 2022-09-02 | 2025-04-08 | 爱普宁公司(特拉华) | 治疗睡眠呼吸暂停的方法和组合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US7160898B2 (en) * | 2001-12-14 | 2007-01-09 | Board Of Trustees Of The University Of Illinois | Pharmacological treatment for sleep apnea |
| PT1257277E (pt) * | 2000-02-24 | 2005-09-30 | Pharmacia & Upjohn Co Llc | Novas combinacoes de farmacos |
| CH695982A5 (de) * | 2001-03-06 | 2006-11-15 | Lilly Co Eli | Inhibitor der Monaminaufnahme. |
| US20050176680A1 (en) * | 2003-12-11 | 2005-08-11 | Sepracor, Inc. | Combination of sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
| US20080145318A1 (en) * | 2006-12-13 | 2008-06-19 | Midha Kamal K | Atomoxetine formulations and associated methods |
| JP2012176958A (ja) * | 2012-04-20 | 2012-09-13 | Watson Pharmaceuticals Inc | (r)−オキシブチニンおよび(r)−デスエチルオキシブチニンによる平滑筋機能亢進の処置 |
| CN106714790A (zh) * | 2014-07-22 | 2017-05-24 | 托马斯·P·杜利 | 使用β肾上腺素能受体拮抗剂和毒蕈碱受体拮抗剂组合的治疗惊恐和焦虑症状的药物组合物和方法 |
| AU2018260666B2 (en) * | 2017-04-28 | 2022-07-21 | The Brigham And Women's Hospital, Inc. | Methods and compositions for treating sleep apnea |
-
2019
- 2019-07-23 WO PCT/US2019/043065 patent/WO2020091862A1/en not_active Ceased
- 2019-07-23 JP JP2021523282A patent/JP2022506113A/ja active Pending
- 2019-07-23 MX MX2021004883A patent/MX2021004883A/es unknown
- 2019-07-23 CN CN201980071524.0A patent/CN112930179A/zh active Pending
- 2019-07-23 AU AU2019370091A patent/AU2019370091A1/en not_active Abandoned
- 2019-07-23 CA CA3117766A patent/CA3117766A1/en active Pending
- 2019-07-23 US US17/289,832 patent/US20210401790A1/en not_active Abandoned
- 2019-07-23 EP EP19749533.6A patent/EP3873454A1/en active Pending
- 2019-07-23 KR KR1020217013074A patent/KR20210084481A/ko not_active Ceased
-
2021
- 2021-04-28 MX MX2024013184A patent/MX2024013184A/es unknown
-
2024
- 2024-04-08 JP JP2024062027A patent/JP2024088740A/ja active Pending
- 2024-12-18 US US18/985,496 patent/US20250114321A1/en not_active Abandoned
-
2025
- 2025-06-30 US US19/254,231 patent/US20250325510A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2024013184A (es) | 2024-12-06 |
| JP2022506113A (ja) | 2022-01-17 |
| CA3117766A1 (en) | 2020-05-07 |
| EP3873454A1 (en) | 2021-09-08 |
| US20210401790A1 (en) | 2021-12-30 |
| WO2020091862A1 (en) | 2020-05-07 |
| JP2024088740A (ja) | 2024-07-02 |
| US20250325510A1 (en) | 2025-10-23 |
| CN112930179A (zh) | 2021-06-08 |
| KR20210084481A (ko) | 2021-07-07 |
| US20250114321A1 (en) | 2025-04-10 |
| AU2019370091A1 (en) | 2021-05-27 |
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