MX2021000796A - Composiciones de partículas terapéuticamente activas con superficie modificada por congelación ultra-rápida. - Google Patents
Composiciones de partículas terapéuticamente activas con superficie modificada por congelación ultra-rápida.Info
- Publication number
- MX2021000796A MX2021000796A MX2021000796A MX2021000796A MX2021000796A MX 2021000796 A MX2021000796 A MX 2021000796A MX 2021000796 A MX2021000796 A MX 2021000796A MX 2021000796 A MX2021000796 A MX 2021000796A MX 2021000796 A MX2021000796 A MX 2021000796A
- Authority
- MX
- Mexico
- Prior art keywords
- ultra
- compositions
- therapeutically active
- active particles
- rapid freezing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Las composiciones farmacéuticas que contienen menos del 10% de un excipiente y se presentan como nanoagregados se describen en la presente. Se ha demostrado que estas composiciones farmacéuticas presentan propiedades mejoradas tales como la mejora de la aerosolizabilidad y el comportamiento aerodinámico. También se proporcionan en la presente métodos para preparar las composiciones farmacéuticas descritas en la presente y uso de los mismos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862702674P | 2018-07-24 | 2018-07-24 | |
PCT/US2019/043202 WO2020023614A1 (en) | 2018-07-24 | 2019-07-24 | Compositions of surface-modified therapeutically active particles by ultra-rapid freezing |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021000796A true MX2021000796A (es) | 2021-06-15 |
Family
ID=69181152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021000796A MX2021000796A (es) | 2018-07-24 | 2019-07-24 | Composiciones de partículas terapéuticamente activas con superficie modificada por congelación ultra-rápida. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20210338671A1 (es) |
EP (1) | EP3827260A4 (es) |
JP (1) | JP2021530551A (es) |
KR (1) | KR20210038583A (es) |
CN (1) | CN112673257A (es) |
AU (1) | AU2019311086A1 (es) |
BR (1) | BR112021001290A2 (es) |
CA (1) | CA3106618A1 (es) |
EA (1) | EA202190331A1 (es) |
IL (1) | IL280342A (es) |
MX (1) | MX2021000796A (es) |
WO (1) | WO2020023614A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014186754A2 (en) | 2013-05-16 | 2014-11-20 | Board Of Regents The University Of Texas System | Dry solid aluminum adjuvant-containing vaccines and related methods thereof |
US11918646B2 (en) | 2017-12-11 | 2024-03-05 | Board Of Regents, The University Of Texas System | Dry adjuvanted immune stimulating compositions and use thereof for mucosal administration |
CN113398079B (zh) * | 2020-03-16 | 2024-01-19 | 鲁南制药集团股份有限公司 | 一种注射用氟达拉滨冻干粉 |
MX2023002465A (es) * | 2020-09-03 | 2023-03-23 | Philip Morris Products Sa | Composiciones en polvo activas de baja higroscopicidad secadas por congelacion. |
US11793808B2 (en) | 2021-02-22 | 2023-10-24 | Mannkind Corp. | Compositions of clofazimine, combinations comprising them, processes for their preparation, uses and methods comprising them |
JP2024510209A (ja) * | 2021-03-12 | 2024-03-06 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | 懸濁液ベースの薄膜凍結を用いて乾燥粉末を調製するための方法 |
US20220321859A1 (en) | 2021-03-25 | 2022-10-06 | Korea Advanced Institute Of Science And Technology | Real-time omnidirectional stereo matching method using multi-view fisheye lenses and system thereof |
CN113484469B (zh) * | 2021-06-30 | 2022-11-18 | 中国科学院青海盐湖研究所 | 水合盐体系相变储能材料纳米尺度相分离的原位表征方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7521068B2 (en) * | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
US20120269721A1 (en) * | 2009-10-12 | 2012-10-25 | The Regents Of The University Of California | Targeted nanoclusters and methods of their use |
US20180147161A1 (en) * | 2015-05-01 | 2018-05-31 | Board Of Regents, The University Of Texas System | Multidrug brittle matrix compositions |
-
2019
- 2019-07-24 AU AU2019311086A patent/AU2019311086A1/en active Pending
- 2019-07-24 BR BR112021001290-7A patent/BR112021001290A2/pt unknown
- 2019-07-24 US US17/262,313 patent/US20210338671A1/en active Pending
- 2019-07-24 EP EP19840589.6A patent/EP3827260A4/en active Pending
- 2019-07-24 EA EA202190331A patent/EA202190331A1/ru unknown
- 2019-07-24 WO PCT/US2019/043202 patent/WO2020023614A1/en unknown
- 2019-07-24 MX MX2021000796A patent/MX2021000796A/es unknown
- 2019-07-24 JP JP2021503813A patent/JP2021530551A/ja active Pending
- 2019-07-24 CN CN201980055623.XA patent/CN112673257A/zh active Pending
- 2019-07-24 KR KR1020217005060A patent/KR20210038583A/ko unknown
- 2019-07-24 CA CA3106618A patent/CA3106618A1/en active Pending
-
2021
- 2021-01-21 IL IL280342A patent/IL280342A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA3106618A1 (en) | 2020-01-30 |
CN112673257A (zh) | 2021-04-16 |
KR20210038583A (ko) | 2021-04-07 |
EP3827260A4 (en) | 2022-05-04 |
WO2020023614A1 (en) | 2020-01-30 |
EP3827260A1 (en) | 2021-06-02 |
JP2021530551A (ja) | 2021-11-11 |
AU2019311086A1 (en) | 2021-02-04 |
US20210338671A1 (en) | 2021-11-04 |
IL280342A (en) | 2021-03-25 |
BR112021001290A2 (pt) | 2021-04-27 |
EA202190331A1 (ru) | 2021-06-17 |
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