MX2021000373A - Composiciones de haloperoxidasa y usos de las mismas. - Google Patents

Composiciones de haloperoxidasa y usos de las mismas.

Info

Publication number
MX2021000373A
MX2021000373A MX2021000373A MX2021000373A MX2021000373A MX 2021000373 A MX2021000373 A MX 2021000373A MX 2021000373 A MX2021000373 A MX 2021000373A MX 2021000373 A MX2021000373 A MX 2021000373A MX 2021000373 A MX2021000373 A MX 2021000373A
Authority
MX
Mexico
Prior art keywords
haloperoxidase
subject
lipid
activity
compositions
Prior art date
Application number
MX2021000373A
Other languages
English (en)
Inventor
Robert C Allen
Jackson T Stephens
Original Assignee
Robert C Allen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert C Allen filed Critical Robert C Allen
Publication of MX2021000373A publication Critical patent/MX2021000373A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/20—Animals treated with compounds which are neither proteins nor nucleic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0337—Animal models for infectious diseases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
    • C12Y111/01—Peroxidases (1.11.1)
    • C12Y111/01007—Peroxidase (1.11.1.7), i.e. horseradish-peroxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
    • C12Y111/02—Oxidoreductases acting on a peroxide as acceptor (1.11) with H2O2 as acceptor, one oxygen atom of which is incorporated into the product (1.11.2)
    • C12Y111/02002—Myeloperoxidase (1.11.2.2)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Un método para tratar al menos uno de entre septicemia, endotoxemia o una infección bacteriana en un sujeto puede incluir administrar al sujeto una composición que contenga una cantidad terapéuticamente eficaz de una haloperoxidasa. La haloperoxidasa puede ser mieloperoxidasa o peroxidasa de eosinófilos. La haloperoxidasa puede inhibir la actividad del lipopolisacárido o del lípido A en el sujeto; como ejemplo no limitante, la haloperoxidasa no participa en la actividad haloperoxidasa activa, pero está disponible para la unión e inhibición de LPS o Lípido A.
MX2021000373A 2018-07-13 2019-07-11 Composiciones de haloperoxidasa y usos de las mismas. MX2021000373A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862697828P 2018-07-13 2018-07-13
PCT/US2019/041419 WO2020014493A1 (en) 2018-07-13 2019-07-11 Haloperoxidase compositions and uses thereof

Publications (1)

Publication Number Publication Date
MX2021000373A true MX2021000373A (es) 2021-04-12

Family

ID=69142821

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021000373A MX2021000373A (es) 2018-07-13 2019-07-11 Composiciones de haloperoxidasa y usos de las mismas.

Country Status (10)

Country Link
US (1) US20210330755A1 (es)
EP (1) EP3820996A4 (es)
JP (1) JP2021531333A (es)
KR (1) KR20210031720A (es)
CN (1) CN112513258A (es)
AU (1) AU2019302744A1 (es)
CA (1) CA3106240A1 (es)
IL (1) IL279936A (es)
MX (1) MX2021000373A (es)
WO (1) WO2020014493A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114480226B (zh) * 2022-04-02 2023-06-02 华南农业大学 一株阿氏肠杆菌及其在防治植物细菌性软腐病中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4063317B2 (ja) * 1991-02-21 2008-03-19 エクソゼミス，インコーポレイテッド 感染治療および叢制御の方法および組成物
US5389369A (en) * 1991-02-21 1995-02-14 Exoxemis, Inc. Halo peroxidase containing compositions for killing yeast and sporular microorganisms
US5888505A (en) * 1991-02-21 1999-03-30 Eoe, Inc. Method for selectively inhibiting the growth of microbes using a haloperoxidase-halide-peroxide system
US8945540B2 (en) * 2008-05-09 2015-02-03 Exoxemis, Inc. Compositions for enhancing the antibacterial activity of myeloperoxidase and methods of use thereof
EP2731601A4 (en) * 2011-07-11 2015-03-04 Exoxemis Inc EOSINOPHILIC PEROXIDASE COMPOSITIONS AND METHOD FOR THEIR USE
US9814234B2 (en) * 2014-01-14 2017-11-14 Exoxemis, Inc. Bioactive heme-haloperoxidase compositions and methods of their use
CN109414485B (zh) * 2016-05-27 2022-08-12 埃欧艾米斯公司 用于抑制脂多糖和脂质a的髓过氧化物酶组合物和方法

Also Published As

Publication number Publication date
EP3820996A1 (en) 2021-05-19
CN112513258A (zh) 2021-03-16
WO2020014493A1 (en) 2020-01-16
AU2019302744A1 (en) 2021-02-04
JP2021531333A (ja) 2021-11-18
US20210330755A1 (en) 2021-10-28
IL279936A (en) 2021-03-01
KR20210031720A (ko) 2021-03-22
CA3106240A1 (en) 2020-01-16
EP3820996A4 (en) 2022-04-27

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