MX2020011575A - Un sistema mejorado de interrogacion de masa de baja energia y ensayo para determinar niveles de vitamina d. - Google Patents
Un sistema mejorado de interrogacion de masa de baja energia y ensayo para determinar niveles de vitamina d.Info
- Publication number
- MX2020011575A MX2020011575A MX2020011575A MX2020011575A MX2020011575A MX 2020011575 A MX2020011575 A MX 2020011575A MX 2020011575 A MX2020011575 A MX 2020011575A MX 2020011575 A MX2020011575 A MX 2020011575A MX 2020011575 A MX2020011575 A MX 2020011575A
- Authority
- MX
- Mexico
- Prior art keywords
- assay
- levels
- power mass
- improved low
- interrogation system
- Prior art date
Links
Classifications
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0022—Portable spectrometers, e.g. devices comprising independent power supply, constructional details relating to portability
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/025—Detectors specially adapted to particle spectrometers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
- H01J49/067—Ion lenses, apertures, skimmers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/20—Magnetic deflection
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/24—Vacuum systems, e.g. maintaining desired pressures
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0013—Miniaturised spectrometers, e.g. having smaller than usual scale, integrated conventional components
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/28—Static spectrometers
- H01J49/30—Static spectrometers using magnetic analysers, e.g. Dempster spectrometer
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/44—Energy spectrometers, e.g. alpha-, beta-spectrometers
- H01J49/46—Static spectrometers
- H01J49/48—Static spectrometers using electrostatic analysers, e.g. cylindrical sector, Wien filter
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plasma & Fusion (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Un montaje de espectrómetro de masas de baja energía incluye al menos un componente de ionización, un analizador electrostático, un montaje de lente, un montaje de imán y al menos un detector ubicado en un mismo plano que la entrada al montaje de imán para detectar los iones de muestra desviados y/o fragmentos de iones de muestra, incluidos iones o fragmentos de iones indicativos del metabolito de vitamina D dentro de la muestra.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862664636P | 2018-04-30 | 2018-04-30 | |
PCT/US2019/029991 WO2019213130A2 (en) | 2018-04-30 | 2019-04-30 | An improved low-power mass interrogation system and assay for determining vitamin d levels |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020011575A true MX2020011575A (es) | 2021-01-20 |
Family
ID=68291607
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020011575A MX2020011575A (es) | 2018-04-30 | 2019-04-30 | Un sistema mejorado de interrogacion de masa de baja energia y ensayo para determinar niveles de vitamina d. |
Country Status (5)
Country | Link |
---|---|
US (2) | US11227754B2 (es) |
AU (2) | AU2019263158B2 (es) |
CA (2) | CA3097198A1 (es) |
MX (1) | MX2020011575A (es) |
WO (1) | WO2019213130A2 (es) |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1398135A (fr) | 1964-03-27 | 1965-05-07 | Commissariat Energie Atomique | Procédé de stabilisation de sources thermoioniques et source thermoionique conforme à celles obtenues par application dudit procédé ou d'un procédé analogue |
DE1498551A1 (de) * | 1964-09-04 | 1969-03-27 | Varian Mat Gmbh | Massenspektroskop |
GB1153167A (en) | 1966-12-28 | 1969-05-29 | Ass Elect Ind | Improvements in or relating to aperture devices for mass spectrometers |
JPS5917500B2 (ja) | 1981-03-18 | 1984-04-21 | 株式会社東芝 | 中性粒子検出装置 |
US4785172A (en) | 1986-12-29 | 1988-11-15 | Hughes Aircraft Company | Secondary ion mass spectrometry system and method for focused ion beam with parallel ion detection |
GB9026777D0 (en) * | 1990-12-10 | 1991-01-30 | Vg Instr Group | Mass spectrometer with electrostatic energy filter |
US6002130A (en) * | 1991-09-12 | 1999-12-14 | Hitachi, Ltd. | Mass spectrometry and mass spectrometer |
US5317151A (en) * | 1992-10-30 | 1994-05-31 | Sinha Mahadeva P | Miniaturized lightweight magnetic sector for a field-portable mass spectrometer |
US5481110A (en) | 1993-09-22 | 1996-01-02 | Westinghouse Electric Corp | Thin film preconcentrator array |
EP0898784A4 (en) | 1996-04-12 | 2006-08-02 | Perkin Elmer Corp | ION DETECTOR, DETECTOR SYSTEM AND INSTRUMENT USING SAME |
WO1999017865A1 (en) * | 1997-10-07 | 1999-04-15 | University Of Washington | Magnetic separator for linear dispersion and method for producing the same |
US6452167B1 (en) | 1998-05-20 | 2002-09-17 | Sandia National Laboratories | Miniature quadrupole mass spectrometer having a cold cathode ionization source |
DE10321648A1 (de) * | 2003-05-13 | 2004-12-16 | Thermo Electron (Bremen) Gmbh | Verfahren und Vorrichtung für die massenspektrometrische Analyse von Gasen |
WO2005088671A2 (en) | 2004-03-05 | 2005-09-22 | Oi Corporation | Gas chromatograph and mass spectrometer |
US7402799B2 (en) | 2005-10-28 | 2008-07-22 | Northrop Grumman Corporation | MEMS mass spectrometer |
US7649171B1 (en) | 2007-05-21 | 2010-01-19 | Northrop Grumman Corporation | Miniature mass spectrometer for the analysis of biological small molecules |
US20100282966A1 (en) | 2008-05-30 | 2010-11-11 | DH Technologies Development Pte Ltd. | Method and system for vacuum driven mass spectrometer interface with adjustable resolution and selectivity |
FR2942072B1 (fr) | 2009-02-06 | 2011-11-25 | Cameca | Spectrometre de masse magnetique achromatique a double focalisation. |
US7977117B2 (en) | 2009-12-03 | 2011-07-12 | Quest Diagnostics Investments Incorprated | Vitamin D metabolite determination utilizing mass spectrometry following derivatization |
CN103415909B (zh) | 2011-01-05 | 2016-02-03 | 普度研究基金会 | 用于样品分析的系统和方法 |
CN105869982B (zh) * | 2011-02-14 | 2018-06-01 | 麻省理工学院 | 用于质谱分析的方法、装置及系统 |
GB201114573D0 (en) | 2011-08-23 | 2011-10-05 | Univ Sheffield Hallam | Categorisation of biological deposits using matrix assisted laser desorption ionisation mass spectrometry |
GB2561998A (en) | 2012-10-10 | 2018-10-31 | California Inst Of Techn | Mass spectrometer, system comprising the same, and methods for determining isotopic anatomy of compounds |
LU92130B1 (en) | 2013-01-11 | 2014-07-14 | Ct De Rech Public Gabriel Lippmann | Mass spectrometer with optimized magnetic shunt |
WO2014182333A1 (en) | 2013-05-09 | 2014-11-13 | Fomani Arash Akhavan | Vacuum pumps for producing adsorbate-free surfaces |
CN108872614B (zh) * | 2013-09-17 | 2022-06-21 | 生物梅里埃公司 | 用于从维生素d结合蛋白解离维生素d的溶液、相关的检测方法及用途 |
US10656157B2 (en) | 2014-09-24 | 2020-05-19 | Purdue Research Foundation | Rare event detection using mass tags |
US20170131247A1 (en) | 2015-11-09 | 2017-05-11 | Thermo Finnigan Llc | Minimal Spanning Trees for Extracted Ion Chromatograms |
US10872755B2 (en) | 2016-03-17 | 2020-12-22 | Leidos, Inc. | Low power mass analyzer and system integrating same for chemical analysis |
US10515789B2 (en) * | 2017-03-28 | 2019-12-24 | Thermo Finnigan Llc | Reducing detector wear during calibration and tuning |
-
2019
- 2019-04-30 MX MX2020011575A patent/MX2020011575A/es unknown
- 2019-04-30 AU AU2019263158A patent/AU2019263158B2/en active Active
- 2019-04-30 WO PCT/US2019/029991 patent/WO2019213130A2/en active Application Filing
- 2019-04-30 CA CA3097198A patent/CA3097198A1/en active Pending
- 2019-04-30 CA CA3222677A patent/CA3222677A1/en active Pending
- 2019-04-30 US US16/399,441 patent/US11227754B2/en active Active
-
2021
- 2021-12-07 US US17/544,599 patent/US11967495B2/en active Active
-
2023
- 2023-11-29 AU AU2023274139A patent/AU2023274139A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2019213130A3 (en) | 2019-12-19 |
AU2019263158A1 (en) | 2020-11-19 |
CA3222677A1 (en) | 2019-11-07 |
AU2019263158B2 (en) | 2023-12-14 |
WO2019213130A2 (en) | 2019-11-07 |
US11227754B2 (en) | 2022-01-18 |
US20190333747A1 (en) | 2019-10-31 |
US20220093376A1 (en) | 2022-03-24 |
AU2023274139A1 (en) | 2023-12-21 |
CA3097198A1 (en) | 2019-11-07 |
US11967495B2 (en) | 2024-04-23 |
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MX2020011575A (es) | Un sistema mejorado de interrogacion de masa de baja energia y ensayo para determinar niveles de vitamina d. |