MX2020010738A - Formulaciones de ciclosporina para uso en el tratamiento del sindrome de bronquiolitis obliterante (bos). - Google Patents
Formulaciones de ciclosporina para uso en el tratamiento del sindrome de bronquiolitis obliterante (bos).Info
- Publication number
- MX2020010738A MX2020010738A MX2020010738A MX2020010738A MX2020010738A MX 2020010738 A MX2020010738 A MX 2020010738A MX 2020010738 A MX2020010738 A MX 2020010738A MX 2020010738 A MX2020010738 A MX 2020010738A MX 2020010738 A MX2020010738 A MX 2020010738A
- Authority
- MX
- Mexico
- Prior art keywords
- bos
- treatment
- bronchiolitis obliterans
- obliterans syndrome
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a una composición que comprende ciclosporina A (CsA) para uso en la prevención del síndrome de bronquiolitis obliterante (BOS) en un paciente con trasplante de doble PULMON, o para el tratamiento de BOS o para la prevención o retraso de la progresión de BOS en un paciente con trasplante de doble pulmón al que se le ha diagnosticado con BOS, en el que la composición se administra a dicho paciente mediante la inhalación de dicha composición en forma de aerosol que comprende una dosis terapéuticamente eficaz de ciclosporina A.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862656226P | 2018-04-11 | 2018-04-11 | |
EP18172067 | 2018-05-14 | ||
PCT/EP2019/058958 WO2019197406A1 (en) | 2018-04-11 | 2019-04-09 | Cyclosporine formulations for use in the treatment of bronchiolitis obliterans syndrome (bos) |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020010738A true MX2020010738A (es) | 2020-11-09 |
Family
ID=66049232
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020010738A MX2020010738A (es) | 2018-04-11 | 2019-04-09 | Formulaciones de ciclosporina para uso en el tratamiento del sindrome de bronquiolitis obliterante (bos). |
Country Status (13)
Country | Link |
---|---|
US (3) | US11484566B2 (es) |
EP (2) | EP3773664B1 (es) |
JP (2) | JP2021520396A (es) |
CN (1) | CN112105374A (es) |
AU (1) | AU2019253137A1 (es) |
BR (1) | BR112020020564A2 (es) |
CA (1) | CA3094891A1 (es) |
CO (1) | CO2020013427A2 (es) |
DK (1) | DK3773664T3 (es) |
IL (1) | IL277253B2 (es) |
LT (1) | LT3773664T (es) |
MX (1) | MX2020010738A (es) |
WO (1) | WO2019197406A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3069711A1 (en) * | 2015-03-16 | 2016-09-21 | PARI Pharma GmbH | Cyclosporine formulations for use in the prevention or treatment of pulmonary chronic graft rejection |
DK3773664T3 (da) * | 2018-04-11 | 2024-06-17 | Breath Therapeutics Gmbh | Formulering af cyclosporin til anvendelse i behandling af bronchiolitis obliterans syndrom (bos) |
US10736847B2 (en) * | 2018-07-03 | 2020-08-11 | Becton, Dickinson And Company | Inverting device for liposome preparation by centrifugation |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020006901A1 (en) | 1999-02-05 | 2002-01-17 | Aldo T. Iacono | Use of aerosolized cyclosporine for prevention and treatment of pulmonary disease |
WO2003035030A1 (en) | 2001-10-24 | 2003-05-01 | Pari Gmbh | Kit for the preparation of a pharmaceutical composition |
DE102006051512A1 (de) | 2005-12-06 | 2007-06-14 | Pari GmbH Spezialisten für effektive Inhalation | Pharmazeutische Medikamentenzusammensetzungen mit Cyclosporin |
EP3069711A1 (en) * | 2015-03-16 | 2016-09-21 | PARI Pharma GmbH | Cyclosporine formulations for use in the prevention or treatment of pulmonary chronic graft rejection |
DK3773664T3 (da) * | 2018-04-11 | 2024-06-17 | Breath Therapeutics Gmbh | Formulering af cyclosporin til anvendelse i behandling af bronchiolitis obliterans syndrom (bos) |
-
2019
- 2019-04-09 DK DK19715929.6T patent/DK3773664T3/da active
- 2019-04-09 LT LTEPPCT/EP2019/058958T patent/LT3773664T/lt unknown
- 2019-04-09 CA CA3094891A patent/CA3094891A1/en active Pending
- 2019-04-09 CN CN201980025434.8A patent/CN112105374A/zh active Pending
- 2019-04-09 BR BR112020020564-8A patent/BR112020020564A2/pt unknown
- 2019-04-09 EP EP19715929.6A patent/EP3773664B1/en active Active
- 2019-04-09 US US17/046,307 patent/US11484566B2/en active Active
- 2019-04-09 EP EP24172897.1A patent/EP4400119A2/en active Pending
- 2019-04-09 AU AU2019253137A patent/AU2019253137A1/en active Pending
- 2019-04-09 MX MX2020010738A patent/MX2020010738A/es unknown
- 2019-04-09 IL IL277253A patent/IL277253B2/en unknown
- 2019-04-09 WO PCT/EP2019/058958 patent/WO2019197406A1/en unknown
- 2019-04-09 JP JP2020555145A patent/JP2021520396A/ja active Pending
-
2020
- 2020-10-26 CO CONC2020/0013427A patent/CO2020013427A2/es unknown
-
2022
- 2022-09-26 US US17/935,140 patent/US11701403B2/en active Active
-
2023
- 2023-05-23 US US18/321,788 patent/US20230364182A1/en active Pending
-
2024
- 2024-03-07 JP JP2024035414A patent/JP2024069355A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL277253B1 (en) | 2023-12-01 |
US11701403B2 (en) | 2023-07-18 |
US20230364182A1 (en) | 2023-11-16 |
AU2019253137A1 (en) | 2020-11-05 |
US20230128855A1 (en) | 2023-04-27 |
DK3773664T3 (da) | 2024-06-17 |
CN112105374A (zh) | 2020-12-18 |
JP2024069355A (ja) | 2024-05-21 |
EP3773664B1 (en) | 2024-05-01 |
JP2021520396A (ja) | 2021-08-19 |
US11484566B2 (en) | 2022-11-01 |
LT3773664T (lt) | 2024-06-10 |
EP4400119A2 (en) | 2024-07-17 |
BR112020020564A2 (pt) | 2021-01-12 |
US20210077573A1 (en) | 2021-03-18 |
CO2020013427A2 (es) | 2020-11-10 |
CA3094891A1 (en) | 2019-10-17 |
EP3773664A1 (en) | 2021-02-17 |
IL277253B2 (en) | 2024-04-01 |
IL277253A (en) | 2020-10-29 |
WO2019197406A1 (en) | 2019-10-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2021006421A (es) | Anilidas de aminoácidos como moduladores de moléculas pequeñas de interleucinas-17 (il-17). | |
WO2020086759A3 (en) | Composition and method for treating the lungs | |
MX2020010738A (es) | Formulaciones de ciclosporina para uso en el tratamiento del sindrome de bronquiolitis obliterante (bos). | |
EA201490377A1 (ru) | Лечение рассеянного склероза комбинацией лаквинимода и глатирамера ацетата | |
NZ702800A (en) | Methods and compositions for cns delivery of heparan n-sulfatase | |
MX2019012884A (es) | Terapia de combinacion. | |
MX369385B (es) | Productos para cicatrizar heridas tisulares. | |
MX2016009349A (es) | (2s)-n-[(1s)-1-ciano-2-feniletil]-1,4-oxazepan-2-carboxamidas como inhibidores de dipeptidil peptidasa 1. | |
BR112015022197A8 (pt) | uso de um composto para fabricação de um medicamento ou composição farmacêutica para o tratamento de cataplexia | |
RU2017115670A (ru) | Лечение инфекции рсв | |
MX2022003072A (es) | Uso de pridopidina para el tratamiento de la disminucion funcional. | |
MX2019002284A (es) | Sistemas de deposito que comprenden acetato de glatiramer. | |
PH12020551911A1 (en) | Use of riluzole oral disintigrating tablets for treating diseases | |
MX2020007971A (es) | Composiciones y metodos para tratar edema pulmonar o inflamacion pulmonar. | |
MX2021001227A (es) | Composicion que contiene un agente mucolitico para el tratamiento de hipersecrecion de moco y un dispositivo para su dosificacion. | |
MX2022000143A (es) | Metodos novedosos. | |
PH12018502521A1 (en) | Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof | |
AU2018256668A1 (en) | Combination therapy comprising an inhibitor of JAK, CDK and PIM | |
ZA202001568B (en) | Methods and compositions for treating chronic lung diseases | |
WO2015009731A3 (en) | Azacyclic constrained analogs of fty720 | |
PH12020500096A1 (en) | Therapeutic combination of a third generation egfr tyrosine kinase inhibitor and a raf inhibitor | |
MX2017002476A (es) | Composiciones y metodos para prevenir o tratar enfermedades, condiciones o procesos caracterizados por proliferacion de fibroblasto aberrante y matriz extracelular. | |
EA201791525A3 (ru) | Соединения для лечения блокады ремиелинизации при заболеваниях, связанных с экспрессией белка оболочки herv-w | |
MY193963A (en) | Composition for treating joint diseases and kit containing same | |
EA201991531A1 (ru) | Способы лечения композициями линаклотида с отсроченным высвобождением |