MX2020006634A - Formulaciones de surfactantes para inhalacion. - Google Patents
Formulaciones de surfactantes para inhalacion.Info
- Publication number
- MX2020006634A MX2020006634A MX2020006634A MX2020006634A MX2020006634A MX 2020006634 A MX2020006634 A MX 2020006634A MX 2020006634 A MX2020006634 A MX 2020006634A MX 2020006634 A MX2020006634 A MX 2020006634A MX 2020006634 A MX2020006634 A MX 2020006634A
- Authority
- MX
- Mexico
- Prior art keywords
- inhalation
- surfactant formulations
- respirable
- polypeptide
- formulated
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0082—Lung surfactant, artificial mucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4726—Lectins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención está dirigida a formulaciones de partículas de polvo seco, respirables de surfactantes pulmonares que opcionalmente comprenden proteínas y/o polipéptidos surfactantes y que se formulan para el suministro al sistema pulmonar a través de la inhalación.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762609277P | 2017-12-21 | 2017-12-21 | |
PCT/US2018/066435 WO2019126289A1 (en) | 2017-12-21 | 2018-12-19 | Surfactant formulations for inhalation |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020006634A true MX2020006634A (es) | 2021-01-15 |
Family
ID=66995083
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020006634A MX2020006634A (es) | 2017-12-21 | 2018-12-19 | Formulaciones de surfactantes para inhalacion. |
Country Status (7)
Country | Link |
---|---|
US (1) | US20210386664A1 (es) |
EP (1) | EP3727353A4 (es) |
JP (2) | JP7335263B2 (es) |
AU (1) | AU2018392461A1 (es) |
CA (1) | CA3085944A1 (es) |
MX (1) | MX2020006634A (es) |
WO (1) | WO2019126289A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2020006633A (es) * | 2017-12-21 | 2021-01-15 | Civitas Therapeutics Inc | Formulaciones de surfactantes para inhalacion. |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ292186B6 (cs) | 1996-01-24 | 2003-08-13 | Altana Pharma Ag | Způsob výroby práškového prostředku s obsahem plicní povrchově aktivní látky, práškový prostředek a jeho použití |
WO1997035882A1 (en) * | 1996-03-27 | 1997-10-02 | Ortho Pharmaceutical Corporation | Lyophilized pulmonary surfactant peptide compositions |
US6586008B1 (en) | 1999-08-25 | 2003-07-01 | Advanced Inhalation Research, Inc. | Use of simple amino acids to form porous particles during spray drying |
JP2003507410A (ja) | 1999-08-25 | 2003-02-25 | アドバンスト インハレーション リサーチ,インコーポレイテッド | 乾燥粉末製剤からの放出調節 |
US20030091509A1 (en) * | 2000-02-11 | 2003-05-15 | Haefner Dietrich | Novel use of pulmonary surfactant for the prophylaxis and treatment of chronic pulmonary diseases |
DK1455755T3 (da) * | 2001-11-20 | 2013-07-15 | Civitas Therapeutics Inc | Forbedrede partikelsammensætning til levering i lunge |
KR101036058B1 (ko) * | 2002-04-25 | 2011-05-19 | 더 스크립스 리서치 인스티튜트 | 폐질환 증상의 치료 및 예방 |
DK1531794T3 (en) * | 2002-06-28 | 2017-08-28 | Civitas Therapeutics Inc | INHALABLE EPINEPHRIN |
US7582312B2 (en) | 2004-11-15 | 2009-09-01 | Discovery Laboratories, Inc. | Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof |
US8563683B2 (en) * | 2006-07-20 | 2013-10-22 | University Of Rochester | Synthetic lung surfactant and use thereof |
KR20090060348A (ko) * | 2006-09-19 | 2009-06-11 | 디스커버리 래보래토리스, 인크. | 폐 계면활성제 제제 및 점액 클리어런스 촉진 방법 |
US8614255B2 (en) | 2007-08-21 | 2013-12-24 | Civitas Therapeutics, Inc. | Pulmonary pharmaceutical formulations |
CN102049040A (zh) * | 2009-10-30 | 2011-05-11 | 北京隆旗生物科技有限公司 | 人工表面活性物质混合液及其制备与应用 |
PL2723323T3 (pl) * | 2012-03-28 | 2016-05-31 | Discovery Lab Inc | Liofilizacja syntetycznego liposomalnego surfaktantu płucnego |
EP3474832A1 (en) * | 2016-06-24 | 2019-05-01 | Civitas Therapeutics, Inc. | Surfactant formulations for inhalation |
-
2018
- 2018-12-19 AU AU2018392461A patent/AU2018392461A1/en active Pending
- 2018-12-19 MX MX2020006634A patent/MX2020006634A/es unknown
- 2018-12-19 EP EP18890080.7A patent/EP3727353A4/en active Pending
- 2018-12-19 WO PCT/US2018/066435 patent/WO2019126289A1/en unknown
- 2018-12-19 JP JP2020554389A patent/JP7335263B2/ja active Active
- 2018-12-19 CA CA3085944A patent/CA3085944A1/en active Pending
-
2021
- 2021-01-19 US US17/151,873 patent/US20210386664A1/en active Pending
-
2023
- 2023-08-17 JP JP2023133058A patent/JP2023144081A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2023144081A (ja) | 2023-10-06 |
AU2018392461A1 (en) | 2020-07-02 |
JP7335263B2 (ja) | 2023-08-29 |
US20210386664A1 (en) | 2021-12-16 |
EP3727353A1 (en) | 2020-10-28 |
JP2021508734A (ja) | 2021-03-11 |
WO2019126289A1 (en) | 2019-06-27 |
EP3727353A4 (en) | 2021-10-13 |
CA3085944A1 (en) | 2019-06-27 |
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