MX2020006294A - Composiciones de vacunas y método para elaborarlas. - Google Patents

Composiciones de vacunas y método para elaborarlas.

Info

Publication number
MX2020006294A
MX2020006294A MX2020006294A MX2020006294A MX2020006294A MX 2020006294 A MX2020006294 A MX 2020006294A MX 2020006294 A MX2020006294 A MX 2020006294A MX 2020006294 A MX2020006294 A MX 2020006294A MX 2020006294 A MX2020006294 A MX 2020006294A
Authority
MX
Mexico
Prior art keywords
protein
thrombostasin
methods
vaccine compositions
making same
Prior art date
Application number
MX2020006294A
Other languages
English (en)
Inventor
Serge Martinod
Kampen Kent R Van
Original Assignee
Tng Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tng Pharmaceuticals Inc filed Critical Tng Pharmaceuticals Inc
Publication of MX2020006294A publication Critical patent/MX2020006294A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43577Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0003Invertebrate antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

En el presente documento se describen proteínas de fusión que comprenden una proteína de trombostasina truncada que tiene al menos un 85% de homología de secuencia con una proteína de trombostasina, en donde la proteína de trombostasina tiene una deleción de carboxi terminal; y una proteína asociada a la fusión que no es una proteína de trombostasina; se describen adicionalmente proteínas trombostasinas de composiciones de vacunas que tienen una deleción de carboxi terminal, y métodos para inhibir una respuesta a una proteína de trombostasina en un huésped que la necesita, que comprenden las proteínas de fusión o composiciones de vacuna descritas; además se describen métodos para la preparación de una composición de proteína de fusión.
MX2020006294A 2017-12-14 2018-12-13 Composiciones de vacunas y método para elaborarlas. MX2020006294A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762598658P 2017-12-14 2017-12-14
PCT/US2018/065407 WO2019118696A1 (en) 2017-12-14 2018-12-13 Vaccine compositions and methods of making same

Publications (1)

Publication Number Publication Date
MX2020006294A true MX2020006294A (es) 2020-12-03

Family

ID=64959426

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020006294A MX2020006294A (es) 2017-12-14 2018-12-13 Composiciones de vacunas y método para elaborarlas.

Country Status (5)

Country Link
US (2) US11780894B2 (es)
AU (2) AU2018386128B2 (es)
BR (1) BR112020011849A2 (es)
MX (1) MX2020006294A (es)
WO (1) WO2019118696A1 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451992B1 (en) 1998-08-20 2002-09-17 Auburn University Antithrobin nucleotides and proteins from horn fly
US9101557B2 (en) * 2011-04-13 2015-08-11 Auburn University Combination of protein forms for hornfly vaccination

Also Published As

Publication number Publication date
US20210070818A1 (en) 2021-03-11
US20240141000A1 (en) 2024-05-02
BR112020011849A2 (pt) 2020-11-24
AU2018386128A1 (en) 2020-07-02
US11780894B2 (en) 2023-10-10
WO2019118696A1 (en) 2019-06-20
AU2018386128B2 (en) 2024-03-07
AU2024203626A1 (en) 2024-06-20

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