MX2020004332A - Derivado de polietilenglicol y metodo de preparacion del mismo. - Google Patents
Derivado de polietilenglicol y metodo de preparacion del mismo.Info
- Publication number
- MX2020004332A MX2020004332A MX2020004332A MX2020004332A MX2020004332A MX 2020004332 A MX2020004332 A MX 2020004332A MX 2020004332 A MX2020004332 A MX 2020004332A MX 2020004332 A MX2020004332 A MX 2020004332A MX 2020004332 A MX2020004332 A MX 2020004332A
- Authority
- MX
- Mexico
- Prior art keywords
- polyethylene glycol
- glycol derivative
- preparation
- mass production
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33303—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group
- C08G65/33306—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group acyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/76—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and etherified hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
- C07C303/04—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/26—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids
- C07C303/28—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids by reaction of hydroxy compounds with sulfonic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/42—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/68—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a carbon skeleton substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/75—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing singly-bound oxygen atoms bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/04—Saturated ethers
- C07C43/13—Saturated ethers containing hydroxy or O-metal groups
- C07C43/135—Saturated ethers containing hydroxy or O-metal groups having more than one ether bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33303—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group
- C08G65/3331—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group cyclic
- C08G65/33313—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group cyclic aromatic
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/334—Polymers modified by chemical after-treatment with organic compounds containing sulfur
- C08G65/3344—Polymers modified by chemical after-treatment with organic compounds containing sulfur containing oxygen in addition to sulfur
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polyethers (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a un derivado de polietilenglicol y a un método de preparación del mismo. Un proceso de preparación de un derivado de polietilenglicol, de acuerdo con la presente invención, puede proporcionar un novedoso derivado de polietilenglicol que se puede utilizar de varias maneras como un enlazador de fármaco, y es apropiado y efectivo para la producción en masa y es ventajoso en la producción en masa reproducible de productos de alta calidad.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20170146940 | 2017-11-06 | ||
PCT/KR2018/013381 WO2019088800A2 (ko) | 2017-11-06 | 2018-11-06 | 폴리에틸렌글리콜 유도체 및 이의 제조방법 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020004332A true MX2020004332A (es) | 2020-08-03 |
Family
ID=66332612
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020004332A MX2020004332A (es) | 2017-11-06 | 2018-11-06 | Derivado de polietilenglicol y metodo de preparacion del mismo. |
Country Status (10)
Country | Link |
---|---|
US (1) | US11168180B2 (es) |
EP (1) | EP3708561B1 (es) |
JP (1) | JP7258019B2 (es) |
KR (1) | KR102353479B1 (es) |
CN (1) | CN111372911B (es) |
AU (1) | AU2018359088A1 (es) |
BR (1) | BR112020008540A2 (es) |
CA (1) | CA3080915A1 (es) |
MX (1) | MX2020004332A (es) |
WO (1) | WO2019088800A2 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114524943B (zh) * | 2022-04-22 | 2022-09-16 | 天津凯莱英制药有限公司 | 聚乙二醇-甘油衍生物及其中间体各自的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20120134158A (ko) | 2004-03-17 | 2012-12-11 | 안티캔서, 인코포레이티드 | 폴리에틸렌 글리콜(peg) 단백질 결합을 증가시키기 위한 방법 |
EP1857462B9 (en) * | 2005-02-18 | 2013-02-13 | Nof Corporation | Polyoxyalkylene derivative |
JP5515224B2 (ja) * | 2007-02-28 | 2014-06-11 | 日油株式会社 | 多分岐鎖ポリオキシアルキレン誘導体 |
EP2370501A1 (en) * | 2008-12-22 | 2011-10-05 | GE Healthcare Limited | Synthesis of obtaining modified polyethylene glycol intermediates |
JP5364532B2 (ja) * | 2009-10-14 | 2013-12-11 | 株式会社センカファーマシー | ポリエチレングリコールの誘導体およびそれを有効成分として含む抗腫瘍剤 |
JP6638970B2 (ja) * | 2015-06-30 | 2020-02-05 | 株式会社 東北テクノアーチ | ヘテロ型単分散ポリエチレングリコール、ヘテロ型単分散ポリエチレングリコール製造用中間体の製造方法 |
TWI770010B (zh) * | 2016-03-07 | 2022-07-11 | 南韓商韓美藥品股份有限公司 | 聚乙二醇衍生物及其用途 |
-
2018
- 2018-11-06 BR BR112020008540-5A patent/BR112020008540A2/pt not_active Application Discontinuation
- 2018-11-06 WO PCT/KR2018/013381 patent/WO2019088800A2/ko unknown
- 2018-11-06 AU AU2018359088A patent/AU2018359088A1/en not_active Abandoned
- 2018-11-06 CA CA3080915A patent/CA3080915A1/en not_active Abandoned
- 2018-11-06 MX MX2020004332A patent/MX2020004332A/es unknown
- 2018-11-06 EP EP18872534.5A patent/EP3708561B1/en active Active
- 2018-11-06 JP JP2020524291A patent/JP7258019B2/ja active Active
- 2018-11-06 KR KR1020180134964A patent/KR102353479B1/ko active IP Right Grant
- 2018-11-06 US US16/648,443 patent/US11168180B2/en active Active
- 2018-11-06 CN CN201880070863.2A patent/CN111372911B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
AU2018359088A1 (en) | 2020-05-21 |
BR112020008540A2 (pt) | 2020-10-06 |
KR102353479B1 (ko) | 2022-01-21 |
WO2019088800A3 (ko) | 2019-08-01 |
CA3080915A1 (en) | 2019-05-09 |
CN111372911A (zh) | 2020-07-03 |
US20200231749A1 (en) | 2020-07-23 |
WO2019088800A9 (ko) | 2019-06-13 |
US11168180B2 (en) | 2021-11-09 |
JP2021501816A (ja) | 2021-01-21 |
CN111372911B (zh) | 2023-06-13 |
KR20190051856A (ko) | 2019-05-15 |
EP3708561B1 (en) | 2024-05-08 |
EP3708561A4 (en) | 2021-11-03 |
EP3708561A2 (en) | 2020-09-16 |
JP7258019B2 (ja) | 2023-04-14 |
WO2019088800A2 (ko) | 2019-05-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ECSP17081744A (es) | Nuevos derivados hidroxiéster,un proceso para su preparación y composiciones farmacéuticas que los contienen | |
MX366422B (es) | Proceso para preparar un producto lacteo fermentado colado. | |
BR112015023681A2 (pt) | grânulos de farinha de microalgas; processo para preparar os grânulos; uso dos grânulos; e produto alimentício | |
GB2540668A (en) | Sanitary tissue products with free fibers and methods for making same | |
SG11201900277RA (en) | Bio-cellulose sheet, bio-cellulose sheet product, and method for producing bio-cellulose sheet and bio-cellulose sheet product | |
WO2016007617A3 (en) | Pharmaceutical compounding kit | |
PH12020550132A1 (en) | Novel enantiomers of a series of antiviral compounds | |
UY36591A (es) | Proceso para producir material recubierto por extrusión, dicho material recubierto, artículo de dicho material y uso de dicho material | |
MX2018002318A (es) | Proceso mejorado para producir fucoxantina y/o polisacaridos de microalgas. | |
MX2015010085A (es) | Metodo de analisis de la estampacion. | |
BR112015009338A2 (pt) | grânulos de farinha de microalgas, processo para preparar os grânulos, uso dos grânulos, e produto alimentício | |
MX2018004299A (es) | Metodo para la purificacion de ciclohexadec-8-en-1-ona. | |
CO2020002156A2 (es) | Produccion a gran escala de productos líquidos y solidos de trichoderma | |
BR112015032201A8 (pt) | processos para produzir um cacau natural marrom escuro | |
IL246525B (en) | Pomegranate cell culture and methods for its preparation and use | |
PH12016502234A1 (en) | Process for obtaining optically active pirlindole enantiomers and salts thereof | |
MX2020004332A (es) | Derivado de polietilenglicol y metodo de preparacion del mismo. | |
GT201500340A (es) | Una composición, proceso y un kit para el procesamiento del azúcar | |
AU201717348S (en) | Rack | |
SE1551246A1 (en) | Modified wood product and a process for producing said product | |
SG11201809772QA (en) | Method for the production of molded bodies for administration to animals | |
EA201990181A1 (ru) | Получение активированных клостридиальных нейротоксинов | |
AR107238A1 (es) | Proceso para la transformación de aceites esenciales que comprenden linalool | |
RU2016132562A (ru) | Способ получения йогурта с наноструктурированным рибофлавином | |
WO2015145434A3 (en) | A method for producing a dairy product containing chocolate and such dairy product |